Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 6, one copy inherited from each parent, form one of the pairs. Chromosome 6 spans about 171 million base pairs (the building blocks of DNA) and represents between 5.5 percent and 6 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 6 likely contains between 1,100 and 1,600 genes.
Genes on chromosome 6 are among the estimated 20,000 to 25,000 total genes in the human genome.
Agents believed to selectively "restart" genes that limit cancer's growth -- a potential treatment option already in early clinical studies -- instead turn off as many genes as they turn on, a team of researchers from the National Cancer Institute and Johns Hopkins has discovered.
The condition of mice with a genetic blood disease called beta-thalassemia improved significantly following treatment of their blood forming cells with a gene that enabled them to produce the type of hemoglobin normally found only in the fetus.
The technique helps to show how cells modify their own genetic makeup and may allow cancer treatments to be tailored more precisely to a patient's disease.
Navarre researcher, Jaione Valle Turrillas, has identified two genes that could help as targets for pharmaceutical drugs that fight the Staphylococcus aureus bacteria - one of the bacteria which causes most infections in medical implants.
MDA grantees Peter Hedera, a neurologist at Vanderbilt University in Nashville, Tenn., and Nigel Laing, a molecular biologist at the University of Western Australia, were part of a team that identified a fourth gene that, when flawed, leads to distal muscular dystrophy (DD).
Few have heard of the degenerative, deadly disease called Ataxia-telangiectasia (A-T) but a University of Alberta researcher is hoping to provide clues to this mysterious disorder.
Scientists from Novosibirsk are engaged in the development of an unusual vaccine which, apart from being less expensive to produce, safe and painless to administer, is also edible.
Scientists at Dana-Farber Cancer Institute and Brigham and Women's Hospital have prolonged the lives of mice with a rare blood disorder by using an experimental drug that blocks signals promoting runaway growth of blood cells.
Researchers at the University of Pennsylvania School of Medicine report a novel strategy for stimulating the production of utrophin – an important muscle protein in young mice – for muscular dystrophy therapy.
By specifically deleting the adhesion protein d-catenin, which is found exclusively in the brain, researchers at UCLA have found evidence that loss of d-catenin produces severe cognitive and synaptic dysfunction.
Men have been tomcatting around since time immemorial, and some traveled far from home to do it, new research suggests.
Four years after publicly revealing the official draft human genetic sequence, researchers have reached the halfway point in dotting the i's and crossing the t's of the genetic sentences describing how to build a human.
Researchers have developed a new genetic test that can help predict whether parents who have one child with the "isolated" form of cleft lip or palate are likely to have a second child with the same birth defect. Isolated clefts account for 70 percent of all cleft lip and palate cases.
Researchers at the University of Bergen are now able to present new information on the HOX genes – the “software” to design animals. The findings are published in today’s issue of Nature.
The incidence of childhood leukaemia in Britain increased dramatically during the twentieth century. The increase has mainly affected the under-five age group, in whom the risk increased by more than 50 per cent during the second half of the century alone.
A national team of investigators led by psychiatric geneticists at Washington University School of Medicine in St. Louis has identified a gene that appears to be linked to both alcoholism and depression.
One of the most comprehensive studies of the forces that have shaped patterns of human genetic variation has found strong evidence for the action of natural selection, which may help explain why certain people are at risk for a variety of conditions and others are not.
Researchers have proposed a new hypothesis on the cause of autism, suggesting a mixed epigenetic and genetic and mixed de novo and inherited (MEGDI) model.
While the nucleus of a cell may be its command headquarters, mitochondria are equally vital—they are the power plants of the cell, and without them all cellular activity would quickly and irrevocably come to a halt.
Stereotypes about the superior color sense of women may well be rooted in genetics. Brian Verrelli, a researcher at the Biodesign Institute at ASU, is co-collaborator on a study suggesting that natural genetic selection has provided women with a frequent ability to better discriminate between colors than men.
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