Animal Model News and Research

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Scientists have developed the first mouse model Werner’s syndrome

Scientists have developed the first mouse model of a rare disease in which people age rapidly and start developing cancers and other diseases associated with the elderly when they are only about 30 years old.

20 Aug 2004

Stem cell research may one day help cerebral palsy

Natural chemicals that assist healing may one day help transplanted adult stem cells integrate into an injured brain, helping children with cerebral palsy recover lost function, according to researchers at the Medical College of Georgia.

18 Aug 2004

Million-dollar grant to trial potential stem cell therapies to repair injured spinal cords

An Australian team headed by UNSW's Professor Phil Waite has won a million-dollar grant from the NSW Department of Health to trial potential stem cell therapies to repair injured spinal cords.

11 Aug 2004

New direction for research into Sly Syndrome

Findings by a Saint Louis University research team led by the scientist who discovered Sly Syndrome 32 years ago point to a new direction for research into the rare genetic disorder that can cause bone deformities, vision and hearing loss, mental retardation and death in children.

9 Aug 2004

Best approach to removing a diseased thyroid may be from under the arm

The best approach to removing a diseased thyroid, the endocrine gland just under the Adam’s apple that controls the body’s metabolic rate, amazingly may be from under the arm, according to a study published in the August issue of the journal Laryngoscope.

5 Aug 2004

Second case of variant Creutzfeldt-Jakob disease infection that was probably caused by blood transfusion

Research reported in The Lancet this week details the second case of variant Creutzfeldt-Jakob disease (vCJD) infection that was probably caused by blood transfusion. The rogue prion responsible for vCJD was identified at postmortem five years after an elderly person received a blood transfusion from a donor who later developed vCJD.

5 Aug 2004

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

Early intervention with a novel kind of "smart gene therapy" might effectively prevent the organ damage commonly suffered by heart attack victims, suggests a new animal study by researchers at Brigham and Women's Hospital in Boston and Duke University Medical Center.

2 Aug 2004

Transplanted cells are capable of surviving in the brain of immunosuppressed stroked rats

Human neural stem cells proprietary to StemCells, Inc. have been used in a Stanford University study in a preclinical stroke model.

29 Jul 2004

New hereditary spastic paraplegia research

In work reported this week, researchers have taken our understanding of HSP to a new level with the development of an animal model for the disease.

13 Jul 2004

By altering a single gene you could live longer and be thinner

Imagine that by altering the function of a single gene, you could live longer, be thinner and have lower cholesterol and fat levels in your blood.

30 Jun 2004

U-M scientists say Wnt protein prevents obesity by inhibiting fat cell development

Genetically engineered mice, created at the University of Michigan Medical School, are living every dieter's dream.

29 Jun 2004

Animal vaccine shows potential for the development of human SARS immunisation

The current issue of the LANCET provides evidence for the effectiveness of experimental SARS immunisation in animal studies. The preliminary results show the potential for the development of human SARS immunisation.

24 Jun 2004

Anabolic steroids may improve surgical repair of shoulder tears

New research from the University of North Carolina at Chapel Hill indicates that treatment with anabolic steroids may improve surgical repair of massive or recurrent tears of the shoulder's rotator cuff tendons.

24 Jun 2004

Zebrafish research may help determine what causes certain birth defects

Description of dozens of mutations that will help determine the earliest steps in vertebrate development, which take the spherical embryo to a complex creature

24 Jun 2004

Key signal in mice that tells stem cells to commit to becoming fat cells

The Hopkins team discovered that adding a single protein, dubbed BMP4, induced mouse stem cells to become fat cells. A very similar signal is likely to be involved in humans, too, say the scientists.

21 Jun 2004

Drug for multiple sclerosis prevented disease development when tested on animal models

Scientists from the Neurological Sciences Institute at Oregon Health & Science University have shown that an investigative drug for multiple sclerosis and related diseases prevented disease development when tested on animal models.

20 Jun 2004

Postnatal exposure to a mercury preservative commonly used in a number of childhood vaccines can lead to the development of autism-like damage

A new study published online June 8 in the Nature publication, Molecular Psychiatry, indicates that postnatal exposure to thimerosal, a mercury preservative commonly used in a number of childhood vaccines, can lead to the development of autism-like damage in autoimmune disease susceptible mice

11 Jun 2004

Drug commonly used for diabetes might be effective in treating multiple sclerosis

Researchers at the University of Illinois at Chicago are launching a clinical trial to determine whether a drug commonly used for diabetes might be effective in treating multiple sclerosis, an autoimmune disease that affects 350,000 Americans.

10 Jun 2004

Research may help treat muscular dystrophies and other muscle diseases caused by glycosylation defects

Expressing high levels of a sugar-adding protein known as LARGE in mice that lack the protein can prevent muscular dystrophy in these animals, according to studies by researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine.

7 Jun 2004

Vitamin C can increase the severity of spontaneous knee osteoarthritis

High doses of vitamin C increase the severity of spontaneous knee osteoarthritis in an animal model of the disease, according to a new study by Duke University Medical Center researchers.

5 Jun 2004

Animal Model News and Research

Scientists have developed the first mouse model Werner’s syndrome

Stem cell research may one day help cerebral palsy

Million-dollar grant to trial potential stem cell therapies to repair injured spinal cords

New direction for research into Sly Syndrome

Best approach to removing a diseased thyroid may be from under the arm

Second case of variant Creutzfeldt-Jakob disease infection that was probably caused by blood transfusion

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

Transplanted cells are capable of surviving in the brain of immunosuppressed stroked rats

New hereditary spastic paraplegia research

By altering a single gene you could live longer and be thinner

U-M scientists say Wnt protein prevents obesity by inhibiting fat cell development

Animal vaccine shows potential for the development of human SARS immunisation

Anabolic steroids may improve surgical repair of shoulder tears

Zebrafish research may help determine what causes certain birth defects

Key signal in mice that tells stem cells to commit to becoming fat cells

Drug for multiple sclerosis prevented disease development when tested on animal models

Postnatal exposure to a mercury preservative commonly used in a number of childhood vaccines can lead to the development of autism-like damage

Drug commonly used for diabetes might be effective in treating multiple sclerosis

Research may help treat muscular dystrophies and other muscle diseases caused by glycosylation defects

Vitamin C can increase the severity of spontaneous knee osteoarthritis

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