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Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Researchers at McMaster University have discovered a molecular "barcode" system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.

8 Jan 2024

Common inflammation pathway turns anthrax toxin into killer

Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the cardiovascular system.

26 Dec 2023

Home dust chemicals predict asthma and allergies in children

Millions of children worldwide suffer from asthma and allergic rhinitis (AR), two chronic respiratory conditions that significantly impact their quality of life.

21 Dec 2023

New discovery could expand the possibilities for medical use of Botox

PSI researchers have discovered a surprising trick that could expand the possibilities for medical use of botulinun toxin A1, better known under the name Botox, as an active agent.

18 Dec 2023

Study suggests iron accumulation plays a central role in senescence and fibrosis

Researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis.

18 Dec 2023

New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains

Study introduces a novel dry powder aerosol COVID-19 vaccine, showing its effectiveness in inducing strong immune responses and offering protection against various SARS-CoV-2 strains, including Omicron.

15 Dec 2023

Novel drug combinations could protect snakebite victims from devastating injuries

New drug combinations could protect snakebite victims from the devastating, life-changing injuries caused by toxic venom, promising new research led by Liverpool School of Tropical Medicine suggests.

14 Dec 2023

New study unpacks the hidden power of breastfeeding

Breastfeeding, even partially alongside formula feeding, changes the chemical makeup-;or metabolome-;of an infant's gut in ways that positively influence brain development and may boost test scores years later, suggests new CU Boulder research.

13 Dec 2023

Key role of ion and water influx in T cell migration uncovered

Research reveals that T cell migration relies on ion and water influx for actin polymerization and movement, with the WNK1 kinase playing a critical role in regulating these processes, offering new insights into adaptive immunity.

10 Dec 2023

Study links organic Mediterranean diet to improved male fertility

Researchers in Italy have found that a low-carbohydrate organic Mediterranean diet significantly enhances male fertility by increasing testosterone levels and reducing sperm DNA fragmentation, offering new dietary guidelines for improving male reproductive health.

10 Dec 2023

Link between gut dysbiosis and chronic diseases explored in new study

Study explores the ecological causes of gut dysbiosis and its link to human diseases, revealing how imbalances in gut microbiota composition, influenced by host-derived factors like oxygen and nitrate, contribute to various chronic conditions.

5 Dec 2023

Canadian researchers aim to reduce chronic inflammation and comorbidities in HIV patients

To mark the occasion of World AIDS Day, find out how Dr. Madeleine Durand and Andrés Finzi are working to reduce chronic inflammation and the risk of comorbidities in people living with HIV.

30 Nov 2023

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism -; the intrinsic link between metabolism in immune cells and their immune function.

20 Nov 2023

New study unravels the mystery of red wine headaches

A red wine may pair nicely with the upcoming Thanksgiving meal. But for some people, drinking red wine even in small amounts causes a headache.

20 Nov 2023

Study links nanoplastics to Parkinson's disease and dementia

Nanoplastics interact with a particular protein that is naturally found in the brain, creating changes linked to Parkinson's disease and some types of dementia.

17 Nov 2023

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

16 Nov 2023

Fresh risks in ready-to-eat produce: Study reveals how common pathogens lurk in our salads

This research paper delves into the risks of contamination in ready-to-eat fruits and vegetables by enteric pathogens like E. coli, Salmonella, and Listeria, which can lead to foodborne illnesses. It also explores the contamination sources and plant-pathogen interactions, emphasizing the importance of improved safety measures in the food supply chain.

6 Nov 2023

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Researchers report that osteoarthritis is caused by the loss of Gremlin 1 (Grem1)-lineage chondrogenic progenitor cells.

3 Nov 2023

Could the microbiome hold the key to diagnosing and treating biliary tract cancer?

A recent study in "Microorganisms" delves into the relationship between the microbiome and biliary tract cancer, revealing distinct microbial compositions in patients compared to healthy individuals. This research highlights potential diagnostic biomarkers and suggests that altering gut microbial composition might enhance responses to cancer immunotherapy.

24 Oct 2023

Botulism strikes during Rugby World Cup: How sardines benched eight fans in Bordeaux

During the 2023 Rugby World Cup in Bordeaux, France, a food-borne botulism outbreak affected eight people who consumed home-canned sardines at the same restaurant. The report emphasizes the importance of quick diagnosis and public health notifications to control large-scale outbreaks.

17 Oct 2023