Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

Key discovery toward understanding mechanism associated with uncontrollable muscular movements

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Lou Gehrig's and Huntington's exhibit loss of nerve function in different ways, from memory lapses to uncontrollable muscular movements, but it is now believed that these diseases share many common molecular mechanisms.

22 Oct 2004

Molecule that helps DNA replicate may make good target for cancer therapy

In order to divide, cells must first replicate their chromosomes. Cells use an array of proteins to accomplish the job, including a large enzyme complex that synthesizes new strands of DNA.

21 Oct 2004

Researchers trim count of human genes to 20,000-25,000

Scientific description of the finished human genome sequence, reducing the estimated number of human protein-coding genes from 35,000 to only 20,000-25,000, a surprisingly low number for our species.

21 Oct 2004

Researchers have developed a novel drug-antidote pair

In a discovery that could give physicians more control over the actions of medications, researchers at Duke University Medical Center have developed a novel drug pair – a potent anti-coagulant with a matched "antidote."

18 Oct 2004

Bionanotechnology that combines the strengths of nanotechnology and biochemistry to generate a new type of bionanomaterial

A team of University of Florida researchers has created tiny hybrid particles that can speedily root out even one isolated E. coli bacterium lurking in ground beef or provide a crucial early warning alarm for bacteria used as agents of bioterrorism and for early disease diagnosis.

11 Oct 2004

Research shows C. botulinum uses SONO to detect nitric oxide

A deadly bacterium's defense against a mortal molecular enemy illuminates the origins and structure of a vital protein involved in human cell signaling, University of Texas Medical School scientists report in Science Express.

8 Oct 2004

Transatlantic study to help damaged hearts repair themselves

A $6 million, five-year grant from the Parisian Fondation Leduq has set up a transatlantic effort to study ways to help damaged hearts repair themselves, using stem cells from bone marrow, bloodstream, and adult heart tissue.

6 Oct 2004

Patients suffering from diseases as varied as Type II diabetes, Alzheimer's, Parkinson's have one thing in common

Patients suffering from diseases as varied as Type II diabetes, Alzheimer's, Parkinson's and dozens of lesser known maladies have one thing in common: they suffer from a large build up of amyloids

5 Oct 2004

Richard Axel has won the 2004 Nobel Prize in physiology or medicine

Richard Axel of the Columbia University Medical Center has won the 2004 Nobel Prize in Physiology or Medicine along with Linda B. Buck of the Fred Hutchinson Cancer Research Center for clarifying how the olfactory system works.

5 Oct 2004

Functions of the c-myb gene which leukemia cells depend on for proliferation

Today the Proceedings of the National Academy of Sciences publishes a paper by Temple University researchers that details one of the functions of the c-myb gene (which leukemia cells depend on for proliferation), the formation of white blood cells.

27 Sep 2004

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Researchers targeted Nef, a protein responsible for accelerating the development of acquired immunodeficiency syndrome, or AIDS. Nef was targeted with small molecules synthesized by the researchers – molecules that disrupted Nef’s interaction with other proteins.

26 Sep 2004

Study presents multiple lines of evidence against the proposed link between SV40 and human mesotheliomas

Mesothelioma is an aggressive cancer of the chest cavity that kills about 2000 people a year in the United States.

26 Sep 2004

Discovery of how protein in teeth controls bone-like crystals to form steely enamel

Bone and enamel start with the same calcium-phosphate crystal building material but end up quite different in structure and physical properties.

26 Sep 2004

Replication timing assays may allow much earlier cancer detection

Scientists have discovered a DNA sequence that is involved in controlling the timing of DNA replication. Because alterations in DNA replication timing are associated with cancer, this discovery may lead to improved methods for cancer detection.

26 Sep 2004

Genome researchers to look at 1918 Spanish flu

University of Washington researchers will be taking part in a multi-site project examining a portion of the genome of the strain of influenza responsible for the "Spanish Flu" outbreak in 1918.

20 Sep 2004

Protein points to anticancer drug targets

A unique tail at one end of a protein called Ubc12 stabilizes a molecular workshop that assembles the “on-switch cells” used to accelerate cell replication.

20 Sep 2004

New insights into ancient mating and migration patterns in humans

Men have been tomcatting around since time immemorial, and some traveled far from home to do it, new research suggests.

20 Sep 2004

Crohn’s disease may be caused by same bacterium that causes Paratuberculosis or Johne’s disease in cattle, sheep, and goats

A study in this week’s issue of THE LANCET suggests that Crohn’s disease may be caused by Mycobacterium avium subspecies paratuberculosis (MAP), the same bacterium that causes a similar intestinal disorder (known as Paratuberculosis or Johne’s disease) in cattle, sheep, and goats.

17 Sep 2004

A new vector of malaria in Africa called Oveng form

Malaria affects around 600 million people in the world and leads to an annual death toll of over 2 million. It is the world’s most widespread parasitic disease.

16 Sep 2004

Researchers are making inroads to understanding what makes brain tumors so hard to treat

When he's not in the operating room performing surgery, Donald M. O'Rourke, M.D., Associate Professor of Neurosurgery at the University of Pennsylvania School of Medicine is fighting brain tumors from the research laboratory bench.

16 Sep 2004

Molecular Biology News and Research

Further Reading

Key discovery toward understanding mechanism associated with uncontrollable muscular movements

Molecule that helps DNA replicate may make good target for cancer therapy

Researchers trim count of human genes to 20,000-25,000

Researchers have developed a novel drug-antidote pair

Bionanotechnology that combines the strengths of nanotechnology and biochemistry to generate a new type of bionanomaterial

Research shows C. botulinum uses SONO to detect nitric oxide

Transatlantic study to help damaged hearts repair themselves

Patients suffering from diseases as varied as Type II diabetes, Alzheimer's, Parkinson's have one thing in common

Richard Axel has won the 2004 Nobel Prize in physiology or medicine

Functions of the c-myb gene which leukemia cells depend on for proliferation

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Study presents multiple lines of evidence against the proposed link between SV40 and human mesotheliomas

Discovery of how protein in teeth controls bone-like crystals to form steely enamel

Replication timing assays may allow much earlier cancer detection

Genome researchers to look at 1918 Spanish flu

Protein points to anticancer drug targets

New insights into ancient mating and migration patterns in humans

Crohn’s disease may be caused by same bacterium that causes Paratuberculosis or Johne’s disease in cattle, sheep, and goats

A new vector of malaria in Africa called Oveng form

Researchers are making inroads to understanding what makes brain tumors so hard to treat

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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