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Precision medicine revolutionizes outcomes for high-risk pediatric cancer patients

In a world-first, Australian researchers and clinicians have shown that precision medicine – where treatment is tailored to an individual child's cancer – leads to significantly improved outcomes in children with high risk cancer.

6 Jun 2024

Study examines potential dangers of consuming energy drinks for patients with genetic heart diseases

A new study in Heart Rhythm, the official journal of the Heart Rhythm Society, the Cardiac Electrophysiology Society, and the Pediatric & Congenital Electrophysiology Society, published by Elsevier, examined the potential dangers of consuming energy drinks for patients with genetic heart diseases.

6 Jun 2024

Low-dose direct oral anticoagulants linked to increased bleeding risk in Afib patients

Patients with atrial fibrillation (Afib) who took low doses of blood-thinning medications known as direct oral anticoagulants (DOACs) experienced more bleeding episodes during the first three months of treatment and about one in five had high blood levels of the medications, compared with similar patients who took standard doses of the same medications, according to a study published in Blood Advances.

6 Jun 2024

Ultrasound technology breaks blood-brain barrier for glioblastoma treatment

In a major advance for the treatment of the deadly brain cancer glioblastoma, Northwestern Medicine scientists used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy and immunotherapy drug cocktail.

6 Jun 2024

Researchers identify a potential metabolic target for cancer immunotherapy

Researchers at the VIB-KU Leuven Center for Cancer Biology have identified a potential target for cancer immunotherapy.

6 Jun 2024

Common drugs linked to reduced risk of bleeding stroke from brain aneurysm

A new study suggests that people who take a few common drugs may have a decreased risk of having a bleeding stroke due to a ruptured brain aneurysm.

5 Jun 2024

Synergistic cytotoxicity in pancreatic cancer: HDAC, PARP inhibitors, and decitabine show promise

A new research paper was published in Oncotarget's Volume 15 on June 3, 2024, entitled, "Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy."

5 Jun 2024

Artificial intelligence accelerates natural-product antibiotic discovery

Almost a century ago, the discovery of antibiotics like penicillin revolutionized medicine by harnessing the natural bacteria-killing abilities of microbes.

5 Jun 2024

Stanford study reveals link between adaptive myelination and drug addiction

Our brains, even in adulthood, continually adapt to what we do, strengthening or weakening neural pathways as we practice new skills or abandon old habits.

5 Jun 2024

$Preoperative antibiotic treatment does not reduce infection risk after pediatric elbow fracture surgery$

Preoperative antibiotic treatment does not reduce infection risk after pediatric elbow fracture surgery

Antibiotic treatment prior to surgical repair of a pediatric elbow fracture does not reduce the risk for post-operative infection, according to new findings from a team of researchers and surgeons from the University of Missouri School of Medicine.

5 Jun 2024

Researchers discover new biological pathway that drives inflammatory bowel disease

Researchers at the Francis Crick Institute, working with UCL and Imperial College London, have discovered a new biological pathway that is a principal driver of inflammatory bowel disease (IBD) and related conditions, and which can be targeted using existing drugs.

5 Jun 2024

Targeting TGFβ/ROCK2/YAP signaling axis to enhance drug delivery in fibrotic pancreatic cancer

Pancreatic cancer, recognized as one of the deadliest cancers, poses a persistent challenge for medical professionals globally due to its aggressive behavior and resistance to conventional therapies.

5 Jun 2024

New bilateral gene therapy shows promising results in treating genetic hearing loss

A novel gene therapy designed to target a form of inherited deafness restored hearing function in five children who were treated in both ears.

5 Jun 2024

New AI camera technology could offer a future tool for quickly assessing the severity of infections

It might soon be possible to measure a patient’s pulse, breathing, and blood pressure simply by scanning their face.

5 Jun 2024

Emerging strains of resistant ringworm pose new public health threats in the U.S.

Healthcare providers should watch out for new and highly contagious forms of ringworm or jock itch, which are emerging as a potential public health threat, according to a pair of reports.

5 Jun 2024

Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

Bacteria, parasites, viruses-;the immune system tackles them all. At the front line of the human immune response are cells called macrophages, which are responsible for correctly identifying intruders and then directing how the entire immune system responds.

5 Jun 2024

Study uncovers genetic clues to the cause of restless leg syndrome

Scientists have discovered genetic clues to the cause of restless leg syndrome, a condition common among older adults.

5 Jun 2024

Common anti-inflammatory drug could combat deadly gut fungus, study finds

A team of UC Davis Health researchers discovered that a common anti-inflammatory drug, mesalamine, can replace the work of good bacteria in fighting the nasty fungus Candida albicans in the gut.

4 Jun 2024

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Advanced clear cell renal cell carcinoma (ccRCC) is a deadly form of kidney cancer with few treatment options; even with new immunotherapies, only around one in 10 patients ultimately survive.

4 Jun 2024

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model."

4 Jun 2024

Drugs News and Research

Precision medicine revolutionizes outcomes for high-risk pediatric cancer patients

Study examines potential dangers of consuming energy drinks for patients with genetic heart diseases

Low-dose direct oral anticoagulants linked to increased bleeding risk in Afib patients

Ultrasound technology breaks blood-brain barrier for glioblastoma treatment

Researchers identify a potential metabolic target for cancer immunotherapy

Common drugs linked to reduced risk of bleeding stroke from brain aneurysm

Synergistic cytotoxicity in pancreatic cancer: HDAC, PARP inhibitors, and decitabine show promise

Artificial intelligence accelerates natural-product antibiotic discovery

Stanford study reveals link between adaptive myelination and drug addiction

Preoperative antibiotic treatment does not reduce infection risk after pediatric elbow fracture surgery

Researchers discover new biological pathway that drives inflammatory bowel disease

Targeting TGFβ/ROCK2/YAP signaling axis to enhance drug delivery in fibrotic pancreatic cancer

New bilateral gene therapy shows promising results in treating genetic hearing loss

New AI camera technology could offer a future tool for quickly assessing the severity of infections

Emerging strains of resistant ringworm pose new public health threats in the U.S.

Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

Study uncovers genetic clues to the cause of restless leg syndrome

Common anti-inflammatory drug could combat deadly gut fungus, study finds

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

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