Precision Medicine News and Research

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Understanding how natural genetic variation contributes to adaptive responses to low oxygen

Humans are still evolving, and Tatum Simonson, PhD, founder and co-director of the Center for Physiological Genomics of Low Oxygen at University of California School of Medicine, plans to use evolution to improve healthcare for all.

12 Feb 2024

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Once they enter the body, drugs, apart from carrying out their therapeutic function, are biochemically transformed by the action of the metabolic machinery, a process that facilitates their expulsion.

9 Feb 2024

Monash-led study unveils potential long-term treatment for lupus

Researchers assessed Smith (Sm)-specific regulatory T cells (Tregs) efficacy in halting lupus nephritis (LN) by engineering and testing epitope-targeted Tregs for systemic lupus erythematosus (SLE) treatment.

8 Feb 2024

Extra fingers and double hearts: Scientists decode how tiny mutations can derail development

Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.

6 Feb 2024

Personalized medicine offers hope for millions with inflammatory bowel disease

The prevalence of inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is rapidly increasing worldwide, affecting an estimated 6.8 million people.

6 Feb 2024

Proteogenomics provides clues about drug response in acute myeloid leukemia

Doctors have nearly a dozen new targeted drugs to treat patients with acute myeloid leukemia, or AML, yet three of four patients still die within five years.

6 Feb 2024

Closing the Cancer Care Gap with the Power of Precision Oncology

According to American Cancer Society, Cancer causes about 1 in every 6 deaths globally, more than AIDS, tuberculosis, and malaria combined.

From MGI 5 Feb 2024

Revvity showcases cutting-edge solutions at SLAS2024

Revvity presents its continued commitment to expanding the boundaries of human potential through science.

From Revvity 5 Feb 2024

Proteogenomics reveals new target for beating drug resistance in acute myeloid leukemia

Doctors have nearly a dozen new targeted drugs to treat patients with acute myeloid leukemia, or AML, yet three of four patients still die within five years.

2 Feb 2024

Breakthrough recombinase technology ushers in precise, adaptable gene editing

A team of researchers at the Carl Gustav Carus Faculty of Medicine, TUD Dresden University of Technology, led by Prof. Frank Buchholz, has achieved a major breakthrough in genome editing technology.

1 Feb 2024

Identifying essential genetic regions for gestational diabetes with deep learning and cfDNA sequencing

Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication posing significant health risks to both mothers and their newborns. Early detection and treatment of GDM are crucial to prevent adverse outcomes.

1 Feb 2024

Machine learning could personalize diuretic treatment for patients with acute decompensated heart failure

A recent study co-authored by Dr. Matthew Segar, a third-year cardiovascular disease fellow at The Texas Heart Institute and led by his research and residency mentor, University of Texas Southwestern Medical Center's Dr. Ambarish Pandey, utilized a machine learning-based approach to identify, understand, and predict diuretic responsiveness in patients with acute decompensated heart failure (ADHF).

31 Jan 2024

New initiative aims to transform how Alzheimer's disease is diagnosed, treated across healthcare settings

Members of the AD-RIDDLE consortium announced today that they will begin a new initiative that aims to bridge the gap between Alzheimer's research, implementation science, and precision medicine.

31 Jan 2024

Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

A new study in mice shows that replacement of a dysfunctional gene could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disorder in which the muscular walls of the heart progressively weaken and put patients at risk of dangerous irregular heartbeats.

30 Jan 2024

MGI Unveils Comprehensive Expansion of Automation Product Lines for Life Science and Healthcare Research

MGI Tech Co., Ltd. (referred to as MGI), a leading provider of cutting-edge tools and technology for life science and healthcare research, today announced a strategic expansion of its automation product lines.

From MGI 30 Jan 2024

RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

29 Jan 2024

Common biomarker test could be misguiding treatment for some Black women with breast cancer

A common test used to decide whether breast cancer patients should get chemotherapy may be making bad recommendations for some Black women, leading them to forgo chemotherapy when it might have helped, according to new research from the University of Illinois Chicago.

29 Jan 2024

13 new biomarkers could help better predict heart disease risk in people with type 2 diabetes

An international academic consortium has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes.

27 Jan 2024

Plaquetec and the Babraham Institute collaborate on phenotypic screen of coronary artery blood

PlaqueTec, a company identifying endotype-specific biomarkers to advance precision medicine for coronary artery disease (CAD), based at the Babraham Research Campus, and the Flow Cytometry Facility at the Babraham Institute today announced a collaboration to develop a cell phenotyping assay to detect cell subpopulations in human blood.

From PlaqueTec 24 Jan 2024

Researchers propose a new model for classifying Parkinson's disease

An international research team led by Krembil Brain Institute Neurologist and Senior Scientist, Dr. Anthony Lang, has proposed a new model for classifying Parkinson's disease (PD).

23 Jan 2024

Precision Medicine News and Research

Understanding how natural genetic variation contributes to adaptive responses to low oxygen

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Monash-led study unveils potential long-term treatment for lupus

Extra fingers and double hearts: Scientists decode how tiny mutations can derail development

Personalized medicine offers hope for millions with inflammatory bowel disease

Proteogenomics provides clues about drug response in acute myeloid leukemia

Closing the Cancer Care Gap with the Power of Precision Oncology

Revvity showcases cutting-edge solutions at SLAS2024

Proteogenomics reveals new target for beating drug resistance in acute myeloid leukemia

Breakthrough recombinase technology ushers in precise, adaptable gene editing

Identifying essential genetic regions for gestational diabetes with deep learning and cfDNA sequencing

Machine learning could personalize diuretic treatment for patients with acute decompensated heart failure

New initiative aims to transform how Alzheimer's disease is diagnosed, treated across healthcare settings

Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

MGI Unveils Comprehensive Expansion of Automation Product Lines for Life Science and Healthcare Research

RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

Common biomarker test could be misguiding treatment for some Black women with breast cancer

13 new biomarkers could help better predict heart disease risk in people with type 2 diabetes

Plaquetec and the Babraham Institute collaborate on phenotypic screen of coronary artery blood

Researchers propose a new model for classifying Parkinson's disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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