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Japanese researchers identify genetic quirk linked to severe COVID-19

Despite intensive research since the pandemic began, much remains unknown about COVID-19, particularly why it can be so severe in some cases and relatively mild in others.

25 Jul 2023

Unlocking the secrets of asymptomatic COVID-19 infections: HLA-B*15:01 connection revealed

Researchers describe the findings of the COVID-19 Citizen Science Study.

25 Jul 2023

Insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of multiple sclerosis

Researchers pursued insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of MS.

21 Jul 2023

Common genetic variation responsible for mediating SARS-CoV-2 asymptomatic infection

Have you ever wondered why some people never became sick from COVID-19? A study published today in Nature shows that common genetic variation among people is responsible for mediating SARS-CoV-2 asymptomatic infection.

19 Jul 2023

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Researchers used a murine model to demonstrate that functional excision of murine PITPNA eventually led to hyperglycemia in mice.

19 Jul 2023

The brain structure of superagers: identifying demographic, lifestyle, and clinical factors associated with their phenotype

Researchers used machine learning models to assess the physical and primarily mental performance of superagers.

19 Jul 2023

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Researchers develop and characterize a highly specific EpiEditing system using catalytically inactivated catalytically inactivated Cas9.

17 Jul 2023

The genetics of neurogenic inflammation in rosacea

Researchers identify rare genetic variants in families with rosacea.

11 Jul 2023

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Study identified a genome-wide significant association (GWAS) for long coronavirus disease.

6 Jul 2023

Study sheds light on cause of most common congenital heart defect

Bicuspid aortic valve is the most common congenital defect in humans, affecting between 1% and 2% of the population. Instead of the usual three symmetric leaflets, affected individuals have two asymmetric valve leaflets.

5 Jul 2023

Study finds that genetically determined milk intake does not increase type-2 diabetes risk

Researchers investigate the association between the genetic basis of milk consumption and type 2 diabetes risk.

3 Jul 2023

First genetic marker for MS severity discovered

Scientists identify the first genetic marker for MS severity, opening the door to preventing long-term disability.

28 Jun 2023

Research explains mechanisms behind anti-viral protection in hemochorial placentas

Give credit to your dad's gene for keeping you safe during those long months in your mother's womb.

20 Jun 2023

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Researchers evaluated the function of the zinc finger transcription factor ROB1 and its two phenotypically distinct alleles in the pathogenesis of Candida albicans infections.

20 Jun 2023

Could mutated blood cells hold the key to lower Alzheimer's risk?

Researchers tested whether clonal hematopoiesis of indeterminate potential (CHIP) status was associated with Alzheimer's disease.

19 Jun 2023

Study improves the genetic knowledge of human eyebrow appearance

The first gene mapping study on eyebrow thickness in Europeans discovered three previously unreported genetic loci, as reported in a Letter to the Editor in the Journal of Investigative Dermatology, published by Elsevier.

5 Jun 2023

"Deep sequencing" of the genome informs diagnoses and treatment of vascular anomalies

Researchers from Children's Hospital of Philadelphia (CHOP) recently discovered that extremely thorough "deep sequencing" of the genome in tissue samples and cell-free DNA of patients with potentially life-threatening vascular anomalies captured several genetic variants related to disease that were not captured with conventional genetic sequencing methods.

1 Jun 2023

Multi-ethnic genome study unlocks new genetic links to health conditions

Research explores the genetic architecture of circulating metabolites, uncovering novel variant-metabolite associations and validating previous findings. It provides insights into the genetic contribution to metabolite levels and potential implications for human disease.

31 May 2023

High HDL-C levels and cardiovascular risks - what you need to know!

Research paper investigates the relationship between very high levels of high-density lipoprotein cholesterol (HDL-C) and cardiovascular outcomes in the general population. The study reveals that while men with high HDL-C face an increased risk of all-cause death and cardiovascular death, this association is not observed in women without coronary artery disease.

22 May 2023

Gout unveiled as surprising culprit in neurodegenerative diseases

Research highlights the association between gout and neurodegenerative diseases, revealing that gout patients exhibit smaller brain volumes, increased brain iron markers, and a higher incidence of conditions such as dementia, Parkinson's disease, and essential tremor, particularly within the first three years after diagnosis.

22 May 2023

Allele News and Research

Japanese researchers identify genetic quirk linked to severe COVID-19

Unlocking the secrets of asymptomatic COVID-19 infections: HLA-B*15:01 connection revealed

Insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of multiple sclerosis

Common genetic variation responsible for mediating SARS-CoV-2 asymptomatic infection

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

The brain structure of superagers: identifying demographic, lifestyle, and clinical factors associated with their phenotype

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

The genetics of neurogenic inflammation in rosacea

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Study sheds light on cause of most common congenital heart defect

Study finds that genetically determined milk intake does not increase type-2 diabetes risk

First genetic marker for MS severity discovered

Research explains mechanisms behind anti-viral protection in hemochorial placentas

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Could mutated blood cells hold the key to lower Alzheimer's risk?

Study improves the genetic knowledge of human eyebrow appearance

"Deep sequencing" of the genome informs diagnoses and treatment of vascular anomalies

Multi-ethnic genome study unlocks new genetic links to health conditions

High HDL-C levels and cardiovascular risks - what you need to know!

Gout unveiled as surprising culprit in neurodegenerative diseases

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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