Mammalian Cells News and Research

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Newly-discovered mechanism may help prevent the build-up toxic proteins in dementia

It's often said that a little stress can be good for you. Now scientists have shown that the same may be true for cells, uncovering a newly-discovered mechanism that might help prevent the build-up of tangles of proteins commonly seen in dementia.

6 May 2022

Study investigates the production of a virosome-based COVID-19 vaccine candidate

In a new study, different signal peptides, baculovirus transfer vectors, cell lines, infection techniques, and formulation buffers were investigated with the purpose of building a scalable bioprocess to generate high-quality S protein for incorporation in a virosome-based COVID-19 vaccine candidate.

18 Apr 2022

Developing and manufacturing custom recombinant antibodies for R&D

In this interview, Dr. Linlin Zhang, technical specialist for Sino Biological Europe, discusses how Sino is expanding its product offerings into the European market and outlines its process for developing and manufacturing custom recombinant antibodies for their clients.

From Sino Biological Inc. 6 Apr 2022

Researchers discover a cell plasticity and inflammation driving druggable copper-signaling pathway

A new study identified mechanisms regulating immune cell plasticity to develop new therapeutics.

31 Mar 2022

The importance of the endosomal pathway for SARS-CoV-2 entry

Researchers demonstrated that combined inhibition of cell-surface-based and endosomal pathways completely blocked SARS-CoV-2 entry into mammalian cells.

21 Mar 2022

RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether.

17 Mar 2022

Potential Covid-19 vaccine may offer an inexpensive, easy-to-store alternative to RNA vaccines

While many people in wealthier countries have been vaccinated against Covid-19, there is still a need for vaccination in much of the world.

16 Mar 2022

Engineered SARS-CoV-2 immunogens elicit broadly neutralizing antibodies

New research describes a novel approach whereby SARS-2 antigens were analyzed for conserved sites that may be targeted by broadly neutralizing antibodies that will confer immunity to other Sarbecoviruses.

10 Mar 2022

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

In a review published in the International Journal of Molecular Sciences, researchers have been reviewing the use of siRNAs to target coronaviruses.

25 Feb 2022

Evaluating effects of D614G and P681R/H mutations on SARS-CoV-2 VOCs

Researchers evaluate how the D614G and P681H mutations alter the attributes of SARS-CoV-2 VOCs.

3 Feb 2022

‘Lefty’ protein pumps the brakes during initial stages of embryo differentiation

A protein known as Lefty pumps the brakes as human embryos begin to differentiate into the bones, soft tissues and organs that make us.

25 Jan 2022

Scientists develop new drug delivery system for treating genetic diseases

A team of researchers led by Harvard and Broad Institute scientists has developed a new drug delivery system using engineered DNA-free virus-like particles (eVLPs) to package and deliver therapeutic levels of gene-editing proteins to animal models of disease.

22 Jan 2022

Discovery illuminates a blueprint to develop new antibiotics for killing bacteria

The Centers for Disease Control and Prevention estimates that more than 2.8 million Americans experience antibiotic-resistant infections each year; more than 35,000 die from those infections.

20 Jan 2022

Study identifies cellular receptors for alphaviruses shared across mosquitoes, humans, and animals

A new study led by researchers at Harvard Medical School has identified a set of cellular receptors for at least three related alphaviruses shared across mosquitoes, humans, and animals that host the virus.

17 Jan 2022

How diet, supplements and lifestyle changes can help battle COVID

A recent editorial in the journal Nutrients emphasizes how efficacious non-pharmacological interventions in conjunction with the promotion of healthy lifestyle and dietary patterns may improve overall health status and reduce the risk of infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as the potential adverse effects of coronavirus disease 2019 (COVID-19).

6 Jan 2022

Mammalian Cells News and Research

Newly-discovered mechanism may help prevent the build-up toxic proteins in dementia

Study investigates the production of a virosome-based COVID-19 vaccine candidate

Developing and manufacturing custom recombinant antibodies for R&D

Researchers discover a cell plasticity and inflammation driving druggable copper-signaling pathway

The importance of the endosomal pathway for SARS-CoV-2 entry

RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Potential Covid-19 vaccine may offer an inexpensive, easy-to-store alternative to RNA vaccines

Engineered SARS-CoV-2 immunogens elicit broadly neutralizing antibodies

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

Evaluating effects of D614G and P681R/H mutations on SARS-CoV-2 VOCs

‘Lefty’ protein pumps the brakes during initial stages of embryo differentiation

Scientists develop new drug delivery system for treating genetic diseases

Discovery illuminates a blueprint to develop new antibiotics for killing bacteria

Study identifies cellular receptors for alphaviruses shared across mosquitoes, humans, and animals

How diet, supplements and lifestyle changes can help battle COVID

Scientists discover a division of labor between genetic switches

Production of functional SARS-CoV-2 spike protein in single-cell green alga

Scientists create a new method to efficiently barcode individual cells

Providing quick & efficient CRO services with Sino Biological

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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