Small Cell Lung Cancer News and Research

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Small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung. Small cell lung cancer is an aggressive (fast-growing) cancer that can spread to other parts of the body. The cancer cells look small and oval-shaped when looked at under a microscope.

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

A new research paper was published in Genes & Cancer on December 14, 2022, entitled, "Slit2 signaling stimulates Ewing sarcoma growth."

13 Jan 2023

Novel bacterial therapy approach opens up new treatment options for lung cancer patients

Lung cancer is the deadliest cancer in the United States and around the world. Many of the currently available therapies have been ineffective, leaving patients with very few options.

26 Dec 2022

Targeted timing of palliative care can have positive impact on life expectancy for lung cancer patients

Choosing the appropriate timing for specialized palliative care can have a positive impact on life expectancy for patients with small cell lung cancer. This is the result of a recently internationally published study by the Karl Landsteiner University of Health Sciences (KL Krems, Austria). There, the relevant data of 152 patients were evaluated at the Krems University Hospital.

19 Dec 2022

New imaging agent lights the way for surgeons during lung cancer surgery

Surgery, especially surgery to remove cancerous tumors, relies on a range of tools and techniques as well as on the skill of the surgeon.

19 Dec 2022

New spatial cell atlas of the developing human lung identifies 144 cell states

The developing human lung has been mapped in unprecedented detail, identifying 144 cell states in the early stages of life, and uncovering new links between developmental cells and lung cancer.

8 Dec 2022

Study suggests new anti-KRAS drug as a strong candidate for pancreatic cancer clinical trials

A small molecule inhibitor that attacks the difficult to target, cancer-causing gene mutation KRAS, found in nearly 30 percent of all human tumors, successfully shrunk tumors or stopped cancer growth in preclinical models of pancreatic cancer, researchers from Penn Medicine's Abramson Cancer Center showed, suggesting the drug is a strong candidate for clinical trials.

6 Dec 2022

Study explores practical pathways to motherhood in women with oncogene-driven lung cancer

New research from the University of Colorado (CU) Cancer Center highlights the need for additional data collection for women hoping to have successful pregnancies while undergoing treatment for lung cancer.

5 Dec 2022

Frequent surveillance imaging not linked to better outcomes following lung cancer surgery

Regular postsurgical screening is critical for patients with lung cancer, the United States' second most prevalent type of cancer and leading cause of cancer deaths.

28 Nov 2022

Simultaneous radiation and immunotherapy can benefit mNSCLC patients with high tumor aneuploidy

In many cancer types, cancer cells try to survive by escaping attack from the immune system. These cancer cells hijack mechanisms called immune checkpoints to trick the immune system into thinking they are healthy cells.

28 Nov 2022

Novel molecular imaging radiotracer can precisely diagnose multiple cancers

A new molecular imaging radiotracer can precisely diagnose a variety of cancers, providing a roadmap to identify patients who may benefit from targeted radionuclide therapies.

20 Nov 2022

Research findings could bolster the effectiveness of immune-checkpoint therapy

Immune checkpoint inhibitors such as Keytruda and Opdivo work by unleashing the immune system's T cells to attack tumor cells.

16 Nov 2022

New breakthrough could help spot lung cancer earlier and improve patient outcomes

Scientists investigating the mechanics of the early stages of lung cancer have identified a new potential treatment, which could also aid early detection of the disease.

8 Nov 2022

Minorities with common form of lung cancer face longer wait times for receiving radiation therapy

A new study has revealed significant racial disparities in how quickly minorities with the most common form of lung cancer receive potentially lifesaving radiation therapy compared with their white counterparts.

25 Oct 2022

Bioinformatics analysis of monkeypox virus-host cell interactions

A recent study posted to the bioRxiv* preprint server reported the interaction between monkeypox and human cells. Molecular sequences were screened to identify differentially expressed genes (DEGs) and their associated signal pathway, expression regulation, and metabolic pathways.

18 Oct 2022

Discovery opens up new approaches to personalized treatment for small cell lung cancer

Small cell lung cancer is a particularly aggressive tumor, which has so far been treated with standardized measures.

6 Oct 2022

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Newly released results from the Phase III ADAURA trial reveal that osimertinib yielded a 5.5-year median disease-free survival in the post-surgical treatment of patients with EGFR-mutated lung cancer, and nearly three in four patients treated with adjuvant osimertinib were disease-free at four years.

12 Sep 2022

Study identifies new therapeutic target against lung adenocarcinoma

The TIMP-1 protein levels in both tissues and blood have been repeatedly associated with a poor prognosis in lung cancers, but its role in this cancer process was, to date, unknown.

12 Sep 2022

Pollutant particles in the air trigger lung cancer in non-smokers

A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies, according to late-breaking data [to be] reported at the ESMO Congress 2022 by scientists of the Francis Crick Institute and University College London, funded by Cancer Research UK. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year.

12 Sep 2022

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

Researchers at the Johns Hopkins Kimmel Cancer Center, three other cancer centers and the Johns Hopkins Bloomberg School of Public Health compiled a comprehensive genetic architecture atlas for mutant RAS genes in human cancers.

8 Sep 2022

CRISPR genome-editing technology can be used as a tool to discover RNA therapeutics for lung cancer

An international team of scientists have demonstrated for the first time that CRISPR genome-editing technology can be used as a tool to find new gene therapies for lung cancer.

24 Aug 2022

Small Cell Lung Cancer News and Research

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

Novel bacterial therapy approach opens up new treatment options for lung cancer patients

Targeted timing of palliative care can have positive impact on life expectancy for lung cancer patients

New imaging agent lights the way for surgeons during lung cancer surgery

New spatial cell atlas of the developing human lung identifies 144 cell states

Study suggests new anti-KRAS drug as a strong candidate for pancreatic cancer clinical trials

Study explores practical pathways to motherhood in women with oncogene-driven lung cancer

Frequent surveillance imaging not linked to better outcomes following lung cancer surgery

Simultaneous radiation and immunotherapy can benefit mNSCLC patients with high tumor aneuploidy

Novel molecular imaging radiotracer can precisely diagnose multiple cancers

Research findings could bolster the effectiveness of immune-checkpoint therapy

New breakthrough could help spot lung cancer earlier and improve patient outcomes

Minorities with common form of lung cancer face longer wait times for receiving radiation therapy

Bioinformatics analysis of monkeypox virus-host cell interactions

Discovery opens up new approaches to personalized treatment for small cell lung cancer

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Study identifies new therapeutic target against lung adenocarcinoma

Pollutant particles in the air trigger lung cancer in non-smokers

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

CRISPR genome-editing technology can be used as a tool to discover RNA therapeutics for lung cancer

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