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New medical patent covering the generation of genetically enhanced therapeutic antigens

Morphotek, Inc. announced today the issuance of United States Patent 6,737,268 covering the generation of genetically enhanced therapeutic antigens.

2 Jun 2004

New therapy to send cancer-killing drugs directly to tumours

Disguising a molecule to get it past the body's immune system could greatly enhance the success of a groundbreaking new therapy, Cancer Research UK scientists report in the British Journal of Cancer this week.

2 Jun 2004

Double-punch approach to vaccine design more effective

A study revealing new information about how viral proteins move between cells and alert the immune system suggests that a double-punch approach to vaccine design would make them more effective.

1 Jun 2004

Novel molecular targeting technologies to deliver gene-silencing therapy

Researchers have combined novel molecular targeting technologies to deliver gene-silencing therapy specifically to tumor cells shielded by a normally impermeable obstacle, the blood brain barrier.

1 Jun 2004

Blueprint for rational design of vaccines that induce desired T-cell responses

Investigators from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have conducted studies in mice to gain a new picture of how the immune system’s “killer” T cells are prompted to destroy infected cells. Their insights provide a blueprint for rational design of vaccines that induce desired T-cell responses.

27 May 2004

New target of a cancer-causing gene

Researchers from the Johns Hopkins Bloomberg School of Public Health and other institutions have identified a new target of a cancer-causing gene.

27 May 2004

Research into flipping genes therapy by Leeds University

Graham Cook and Erica de Wynter of molecular medicine have secured £125,000 to investigate the unique way antibody genes are assembled and how they can be harnessed to fight disease.

25 May 2004

Possible new second-generation multiple sclerosis therapy

Scientists from Genencor International, Inc., have demonstrated in an in vivo model that a new variant of recombinant interferon-beta reduces the immunological response to the protein.

25 May 2004

Researchers have isolated a protein receptor in chickens responsible for transferring antibodies from mother to offspring

Howard Hughes Medical Institute (HHMI) researchers have isolated a protein receptor in chickens that is responsible for transferring antibodies from mother to offspring - a function critical to bestowing a temporary immunity that protects the young against infection until their own immune systems begin functioning.

24 May 2004

Study shows herpes is common in suburban populations, with Denver up to 20 percent

According to a recent study of 36 primary care physician (PCP) offices in relatively affluent suburban areas of six U.S. cities, one in four people (25.5 percent) tested positive for the virus that causes genital herpes, despite the fact that only four percent of all those tested reported a history of the condition.

24 May 2004

Clinical use of immunoassays not recommended as a primary means of assessing environmental fungal exposure

Routine clinical use of immunoassays, a type of blood test for measuring antigen-specific IgE or IgG antibodies, is not recommended as a primary means of assessing environmental fungal exposure or its harmful effects according to a report published this month in Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

24 May 2004

The number of antibody-based medicines will climb dramatically

The number of antibodies in clinical development has leapt over the past six years and in 2004 hundreds are currently making their way through trials in what surely will be a spate of new product introductions beginning in 2004 and continuing over the next 10 years.

15 May 2004

Minority women are disproportionately impacted by the autoimmune disease lupus

There is an urgent need for more education and research to address the fact that minority women are disproportionately impacted by the autoimmune disease lupus

14 May 2004

Cholesterol-lowering drugs could treat multiple sclerosis

Drug treatments for MS are expensive and only partially effective. Recent knowledge that statins promote an anti-inflammatory response from the immune system suggest a potential in the treatment of MS.

13 May 2004

Nanobodies herald a new era in cancer therapy

Cancer, along with heart and vascular disease, is the major cause of death in the Western world. The first generation of anti-cancer drugs has already saved many lives, but because these medicines are non-specific they also often have severe side effects.

12 May 2004

Australian researchers are working on a vaccine to prevent rheumatic fever and rheumatic heart disease

The Queensland Institute of Medical Research (QIMR) Australia, is working on a vaccine to prevent rheumatic fever (RF) and rheumatic heart disease (RHD). Rheumatic fever and rheumatic heart disease are a secondary complication of a bacterial infection.

12 May 2004

New mums are being urged to give breastfeeding a go

The UK has one of the lowest breastfeeding rates in Europe. Almost one third of women in England and Wales never try to breastfeed, compared to just two per cent in Sweden. Younger women are the least likely to breastfeed, with two in five mothers under 24 never trying.

10 May 2004

Survey serious misunderstandings about breastfeeding

A survey published today by The UK Department of Health for National Breastfeeding Awareness Week (9 - 15 May) shows that serious misunderstandings may be stopping women, particularly young women, from breastfeeding.

10 May 2004

Discovery of immune system malfunction that plays a profound role in food allergy

A team of scientists, led by the Institute of Food Research (IFR) in the UK, has discovered an immune system malfunction that is likely to play a profound role in food allergy.

8 May 2004

A second-generation targetted antibody for potential cancer therapy

The overproduction, or 'overexpression', of the epidermal growth factor receptor (EGFR) is one of the most common aberrations in cancer, and subsequently agents that inhibit EGFR are among the most hotly-pursued potential products in the pharmaceutical industry.

6 May 2004