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Study highlights the need for liver cirrhosis patients to be educated on hepatic venous pressure gradient

Just like the hypertension that people develop when their blood pressure increases, the increase of blood pressure in the main vein that supplies blood to the liver, called the portal vein, is also a dangerous situation.

31 May 2022

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF).

25 May 2022

Study explores neurologic complications in pediatric COVID-19 cases

Researchers evaluated neurologic complications in pediatric cases of COVID-19.

18 May 2022

Research may lead to more effective interventions for hypoxic-ischemic encephalopathy

One of the most common causes of disability or death in newborns is a lack of oxygen or blood flow in the brain during labor or delivery.

11 May 2022

Researchers report widespread prevalence of reactive and acute inflammatory CNS microvasculopathy in 36 COVID-19 brain autopsies

A new study has focused on the microcirculatory factors associated with neurological complications of COVID-19.

10 May 2022

Approximately 13% of hospitalized COVID patients have serious neurologic symptoms

In a recent study in the journal Critical Care Explorations, the Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry was used to record significant neurologic signs of SARS-CoV-2 infection, as well as prehospital risk factors and outcomes.

9 May 2022

Rapid infusion of NaHCO3 bolus after extensive resuscitation leads to higher blood flows to the brain and heart

A new study examines the effect of rapid infusion of 2meq/kg of sodium bicarbonate (NaHCO3) in an ovine model on gas exchange and coronary and cerebral perfusion in the immediate post-resuscitation phase.

22 Apr 2022

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Alzheimer's disease is marked by a loss of functional neurons in the brain. But what causes this loss? Through single-cell genome sequencing, researchers at Boston Children's Hospital, Brigham and Women's Hospital, and the Broad Institute show that people with Alzheimer's have an abundance of newly acquired mutations in their neurons -; more than people of the same age without Alzheimer's, and enough to disable genes important to brain function.

20 Apr 2022

Severe outcomes in hospitalized children during the Omicron BA.2-dominated fifth wave in Hong Kong

A recent study investigated the disease severity of SARS-CoV-2 Omicron BA.2 infection among Hong Kong children.

28 Mar 2022

University of Kentucky begins world’s first clinical trial for LATE

The motivation driving the work of Pete Nelson, M.D., Ph.D., is personal. His grandmother, Sylvia Becker, died with Alzheimer's disease, and he says his mother then grew terrified of developing the disease.

17 Mar 2022

Current evidence that vitamin D is effective against COVID-19 neurological sequelae

Researchers analyze the available scientific evidence supporting vitamin D as a neuroprotective agent against the neurological sequelae of COVID-19.

14 Mar 2022

Two new studies shed light on tau’s role in Alzheimer’s disease psychosis

Helping to advance Alzheimer’s disease (AD) research, scientists from The Feinstein Institutes for Medical Research have published two studies supporting the connection of tau – a protein in the brain that forms neurofibrillary tangles that are a hallmark of AD and have been linked to chronic traumatic encephalopathy (CTE) from head trauma – with psychosis in AD.

8 Mar 2022

How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

Study to examine the risks for brain disorders from repetitive head impacts in contact sports

Internationally-renowned researchers from Boston University and the University of California, San Francisco) are launching a new study, called the Head Impact & Trauma Surveillance Study (HITSS).

7 Mar 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

The emergence of infectious diseases from the "germ’s eye view”

The study highlighted that the disruption caused by the COVID-19 pandemic has shown that human societies remain ill-prepared and susceptible to novel infectious diseases.

16 Feb 2022

Looking into the long-COVID brain

Neurological issues, ranging from memory lapses to trouble with attention, have been widely reported after recovery from severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection. Unfortunately, there is limited information about pathways to recovery after severe COVID hospitalization. Now, a prospective study of 4,491 patients hospitalized with COVID suggests neurological recovery can take at least a year. The study is currently available on the medRxiv* preprint while awaiting peer review.

13 Feb 2022

Liver cirrhosis has higher hospitalization and in-hospital mortality rates in Germany

In Germany, liver cirrhosis has the highest mortality rate of any chronic disease requiring hospital admission. When diagnosed as a comorbidity of other chronic diseases, liver cirrhosis at least doubles the mortality rate.

12 Feb 2022

Hazards of persistent and new clinical sequelae caused by SARS-CoV-2 infection among elderly patients

A new study estimated the risk and hazards of persistent and new clinical sequelae of the SARS-CoV-2 infection among elderly patients (above 65 years or older) during the post-acute phase of the infection.

11 Feb 2022

Patients undergoing neurosurgical operations with concomitant COVID-19 infection have higher rates of perioperative complications

This unique paper compares neurosurgical patients with COVID-19 for perioperative complications to those without COVID-19.

31 Jan 2022