Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Dr. Anthony Lang reveals new model for studying Parkinson’s disease at the 26th World Congress of Neurology

During a plenary lecture at the 26th World Congress of Neurology, Dr. Anthony Lang, professor of neurology and Jack Clark Chair for Parkinson's Disease Research, University of Toronto, revealed a groundbreaking new model for identifying and studying Parkinson’s disease. This new approach will help researchers investigate biological aspects of the disease that may be detectable many years before symptoms begin to show.

20 Oct 2023

Identifying a signature biomarker for early-onset Alzheimer's disease

Alexandra Touroutoglou, PhD, and Bradford Dickerson, MD, neuroscientists in the department of Neurology at Massachusetts General Hospital, are the lead authors of a new study published in Alzheimer's & Dementia, The Sporadic Early-onset Alzheimer's Disease Signature Of Atrophy: Preliminary Findings From The Longitudinal Early-onset Alzheimer's Disease Study (LEADS) Cohort.

19 Oct 2023

Review highlights the potential mechanistic links between COVID-19 and Alzheimer's disease

The various neurological symptoms that patients with COVID-19 have experienced suggest that viral infections may increase the risk of neurodegeneration, which could in turn contribute to the development of conditions such as Alzheimer's disease (AD).

18 Oct 2023

Study reveals a microbial metabolite's role in inducing Parkinson's-like symptoms

Researchers from the University of Vienna, University of Konstanz, and Albert Einstein College of Medicine uncover a potential environmental trigger for Parkinson's disease.

11 Oct 2023

New AI model can identify neuroanatomical regions vulnerable to age-related changes

The aging brain undergoes structural and cellular changes that can impact function and increase susceptibility to neurodegenerative disorders like Alzheimer's disease.

11 Oct 2023

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Researchers introduced and characterized a novel platform based on monoclonal antibodies (mAbs).

6 Oct 2023

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

Researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2).

4 Oct 2023

Microglial states and their impact on Alzheimer's disease

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

3 Oct 2023

Novel deep learning model to assess Alzheimer's disease progression risk

Patterns in the Alzheimer's disease (AD) trajectory using Mendelian randomization (MR) and deep learning (DL).

3 Oct 2023

Evidence reveals ferroptosis's critical role in male reproductive health

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2 Oct 2023

Parkinson's disease-related neuronal death more likely to occur at night

Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease.

29 Sep 2023

Insights and new directions in basic, clinical research into neurodegenerative diseases

A special supplement to the Journal of Alzheimer's Disease, published by IOS Press, presents insights and new directions in both basic and clinical research into neurodegenerative diseases.

28 Sep 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

Study investigates association between menopause stage and cerebral hemodynamics

Driven by changing estrogen levels, the menopause transition has a major influence on physiology during aging.

27 Sep 2023

Study upends common belief in what triggers Parkinson's disease

A new Northwestern Medicine study challenges a common belief in what triggers Parkinson's disease.

15 Sep 2023

N-acetylglucosamine reduces multiple inflammation and neurodegeneration markers in MS patients

UCI researchers have found that a simple sugar, N-acetylglucosamine, reduces multiple inflammation and neurodegeneration markers in people who suffer from multiple sclerosis (MS).

14 Sep 2023

Researchers discover backup protein quality control mechanism

Researchers from the Babraham Institute, UK, and the German Center for Neurodegenerative Diseases (DZNE) have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail.

14 Sep 2023

Study identifies cellular processes that likely lead to Parkinson's disease

Parkinson's disease, characterized by various motor dysfunctions, is the second most common neurodegenerative disorder in the world. It is known that specific gene mutations that are passed down through families are responsible for some cases of Parkinson's disease.

11 Sep 2023

FAU researchers discover novel method to identify therapeutic agents to treat addiction

According to the Substance Abuse and Mental Health Services Administration, approximately 40 million people in the United States had a substance use disorder in 2020.

8 Sep 2023

Could medicinal plants be the key to reversing cognitive decline?

Researchers explore available evidence that medicinal plants may help improve cognitive function by reducing brain inflammation.

5 Sep 2023