Small Molecules News and Research

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Lipid Nanoparticles (LNPs) and DNA delivery – unlocking the future of medical research

In this interview, Kate Stumpo speaks to Michael Girgis about Lipid nano particles, and the future of the field.

From Bruker Life Sciences Mass Spectrometry 31 Mar 2023

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

A recent review published in Biochemical Pharmacology summarized the ongoing research, providing insights into pathophysiology and emerging drugs for Alzheimer’s disease (AD).

31 Mar 2023

Riboswitch may be the key to advance gene therapy, regenerative medicine

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

30 Mar 2023

New review examines link between HDLC and different types of cancer

Researchers summarized studies on the association between high-density lipoprotein cholesterol and different types of cancer

29 Mar 2023

Discovery suggests a new way to treat spinal muscular atrophy

Columbia researchers have discovered how a genetic defect leads to spinal muscular atrophy (SMA), a critical piece of information about the disease that neurologists have been seeking for decades.

23 Mar 2023

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

A recent Nature Signal Transduction and Targeted Therapy journal study demonstrated the potential antiviral activity of a new Mpro inhibitor (SY110) against SARS-CoV-2 Omicron and its sublineages.

21 Mar 2023

Snapping at new biotech breakthroughs with Gator Pro

In this interview, we speak to Subodh Nimkar, Marketing Director at Gator Bio, about their latest technology, Gator Pro which allows for fast, reliable, and high-quality data.

From Gator Bio, Inc. 21 Mar 2023

AI-based design method synthesizes polymers that mimic blood plasma

Most life on Earth is based on polymers of 20 amino acids that have evolved into hundreds of thousands of different, highly specialized proteins. They catalyze reactions, form backbone and muscle and even generate movement.

20 Mar 2023

Newly identified small molecule may help treat people with drug-resistant epilepsy

Researchers at Tufts University School of Medicine and colleagues have identified a small molecule that may help treat people with epilepsy whose condition has become resistant to the benzodiazepine drugs usually used in managing seizures.

15 Mar 2023

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Scientists at the National Institutes of Health and Massachusetts General Hospital in Boston have uncovered a potential new approach against liver cancer that could lead to the development of a new class of anticancer drugs.

14 Mar 2023

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type.

8 Mar 2023

Gene mutation capable of regulating pain discovered

Pain afflicts at least 1.5 billion people worldwide, and despite the availability of various painkilling drugs, not all forms of pain are treatable.

3 Mar 2023

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

In a recent review published in Biomedicines, researchers explored extracellular vesicles (EVs), cell-penetrating peptides (CPPs), and micro ribonucleic acids (miRNAs) as therapies for neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).

1 Mar 2023

Small Molecules News and Research

Lipid Nanoparticles (LNPs) and DNA delivery – unlocking the future of medical research

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

Riboswitch may be the key to advance gene therapy, regenerative medicine

New review examines link between HDLC and different types of cancer

Discovery suggests a new way to treat spinal muscular atrophy

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

Snapping at new biotech breakthroughs with Gator Pro

AI-based design method synthesizes polymers that mimic blood plasma

Newly identified small molecule may help treat people with drug-resistant epilepsy

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Gene mutation capable of regulating pain discovered

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

First small molecules designed to stimulate immune cells against neuroblastoma

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

Life Sciences Innovator Category Winner 2023

Protein degradation approach can be used to hit an ‘undruggable’ target against cancer

Light-based technology could improve cancer diagnostics

Exploring two small molecules for the disintegration of alpha-synuclein fibrils

Scientists illuminate the mechanisms that prevent p53 activation from triggering cancer cell death

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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