Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

The liver may produce most of the body's good cholesterol

Research in mice suggests that the liver may produce most of the body's "good" cholesterol, an unexpected finding that might one day help scientists develop new treatments to raise levels of this heart-protecting molecule in humans.

10 Apr 2005

Modest triglyceride elevations linked to coronary artery disease risk

Even modest increases in blood levels of triglycerides, as well as a type of high cholesterol known as type III hyperlipidemia, are strongly associated with coronary artery disease in people with a family history of the disease, according to a new study in the April 5, 2005, issue of the Journal of the American College of Cardiology.

5 Apr 2005

Dallas heart study researchers find no link between Lp(a), calcium

The latest findings from the historic Dallas Heart Study have ruled out one of the most prominent explanations of why elevated levels of a fat-carrying protein called "lipoprotein(a)" lead to increased risks for heart attacks among whites but not among African-Americans.

5 Apr 2005

Pcsk9 gene - new target for cholesterol-lowering drugs

Mice lacking a key protein involved in cholesterol regulation have low-density lipoprotein, or "bad" cholesterol, levels more than 50 percent lower than normal mice, and researchers suggest that inhibiting the same protein in humans could lead to new cholesterol-lowering drugs.

29 Mar 2005

Link between high cholesterol and better memory

What's bad for your ticker may be good for your bean, according to a research from a team of scientists at Boston University.

22 Mar 2005

Questions about validity of HOPE TOO vitamin E study

A study published in the March 16 issue of Journal of the American Medical Association (JAMA) suggesting that a "daily-dose" of vitamin E (400 international units) among high-risk (chronically ill) cardiovascular patient populations is associated with a greater risk of heart failure is being challenged by leading health researchers around the country who claim the study lacks the adequate research and controlled sampling audience to justify this conclusion.

16 Mar 2005

Growth hormone treatment may reduce serious metabolic conditions

Researchers in Sweden have discovered that growth hormone (GH) treatment may result in the reduction of multiple metabolic disorders associated with abdominal obesity in postmenopausal women.

14 Mar 2005

Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women

Researchers in Sweden have discovered that growth hormone (GH) treatment may result in the reduction of multiple metabolic disorders associated with abdominal obesity in postmenopausal women.

8 Mar 2005

Dietary fat quality may be more important than fat quantity in reducing risk of cardiovascular deaths in middle-aged men

The type of dietary fats consumed by middle-aged men, especially polyunsaturated fats and linoleic acids, may be more important than total fat intake in reducing the risk of cardiovascular deaths, according to a study in the January 24 issue of Archives of Internal Medicine.

24 Jan 2005

Ascorbic acid doesn't seem to help physical exercise performance

Orange juice or other sources of vitamin C (ascorbic acid), may (or may not) benefit you in terms of health and exercise, but contrary to what many people thought previously, ascorbic acid doesn't seem to help physical exercise performance.

6 Jan 2005

Sticking to one diet plan key to losing weight

A comparison of four popular diet plans finds that the key to losing weight may not be which diet plan a person picks, but sticking with the plan that is chosen, according to a study in the January 5 issue of JAMA.

5 Jan 2005

Course of injections in childhood might help protect people from heart disease later in life

A course of injections in childhood might help protect people from heart disease later in life. And for those whose arteries are already clogged up, a dose of antibodies could provide immediate benefits. That's the enticing vision raised by animal studies.

26 Dec 2004

New way to reduce fat and cholesterol levels in the body

Just in time for the holidays, McGill researchers have identified a new way to reduce fat and cholesterol levels in the body. Their program, which combines consuming plant-derived sterols (or oils) with exercise, may benefit those who are at risk of coronary heart disease.

21 Dec 2004

Chylomicrons may be as dangerous or more dangerous than low-density lipoprotein (LDL) cholesterol

You may not yet have heard of chylomicrons, but a nutritional scientist at the University of Alberta believes you will soon--especially if you care about preventing a stroke or heart attack.

24 Nov 2004

The risk of developing metabolic syndrome increases the more a person drinks

The risk of developing metabolic syndrome increases the more a person drinks – and beginning a heavy drinking pattern early in life seems to add extra risk, according to a first-of-its-kind study presented at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

The cholesterol-lowering drug atorvastatin slowed down mental decline and improved depressive symptoms in people with Alzheimer’s disease, according to a small pilot study reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Metabolic syndrome associated with cognitive decline in elderly persons

Elderly individuals with the metabolic syndrome, a grouping of several common conditions including abdominal obesity, low level of high-density lipoprotein (HDL, the “good cholesterol”), hypertension, and high triglyceride and blood sugar levels, are more likely to experience cognitive impairment than those without this syndrome, according to a study in the November 10 issue of JAMA.

10 Nov 2004

Zetia co-administered with Fenofibrate significantly reduced LDL ("bad") cholesterol in mixed hyperlipidemia patients

Results from a new study showed that coadministration of Zetia (ezetimibe) and fenofibrate significantly reduced LDL ("bad") cholesterol (LDL-C), non-high density lipoprotein cholesterol (non-HDL-C) and apo B1 in patients with mixed hyperlipidemia and high LDL cholesterol when compared to fenofibrate alone.

9 Nov 2004

Cranberry juice may help prevent gum disease

New research presented at a recent symposium suggests that cranberry juice may help prevent certain oral health problems, including diseases of the gums and teeth.

9 Nov 2004

Lipid Sciences' selective delipidation process demonstrates enhanced ability in removing cholesterol from cells

Lipid Sciences announced today that researchers have successfully used the Company's proprietary "selective delipidation" process to create a modified form of HDL ("good cholesterol") that is known to be more effective in reverse cholesterol transport, the body's natural process for removing lipids from arterial plaque.

8 Nov 2004