Lymphocytic Choriomeningitis News and Research

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Lymphocytic choriomeningitis, or LCM, is a rodent-borne viral infectious disease that presents as aseptic meningitis (inflammation of the membrane, or meninges, that surrounds the brain and spinal cord), encephalitis (inflammation of the brain), or meningoencephalitis (inflammation of both the brain and meninges). Its causative agent is the lymphocytic choriomeningitis virus (LCMV), a member of the family Arenaviridae that was initially isolated in 1933. Although LCMV is most commonly recognized as causing neurological disease, as its name implies, infection without symptoms or mild febrile illnesses are common clinical manifestations. Additionally, pregnancy-related infection has been associated with congenital hydrocephalus, chorioretinitis, and mental retardation.
Attenuated virus helps eliminate cancer in mice

Attenuated virus helps eliminate cancer in mice

New discovery could lead to a treatment for visceral leishmaniasis

New discovery could lead to a treatment for visceral leishmaniasis

Low serotonin levels observed in long COVID and other viral infections

Low serotonin levels observed in long COVID and other viral infections

Immature immune cells near dural sinuses linked to neonatal viral meningoencephalitis

Immature immune cells near dural sinuses linked to neonatal viral meningoencephalitis

Research identifies Th1 memory CD4+ T cells as key to protect against emerging poxvirus skin infections

Research identifies Th1 memory CD4+ T cells as key to protect against emerging poxvirus skin infections

The human body develops strategies to prevent the immune response from overshooting its mark

The human body develops strategies to prevent the immune response from overshooting its mark

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

The role of CRISPR in viral diagnostics

The role of CRISPR in viral diagnostics

Study reveals the zoonotic potential of the rat Sialodacryoadenitis virus

Study reveals the zoonotic potential of the rat Sialodacryoadenitis virus

Viral clearance accompanied by persistent footprints

Viral clearance accompanied by persistent footprints

Researchers show SARS-CoV-2 genes can be integrated into the human genome

Researchers show SARS-CoV-2 genes can be integrated into the human genome

Host cell transmembrane protein MARCH8 targets lysine residues to inhibit SARS-CoV-2 and other viruses

Host cell transmembrane protein MARCH8 targets lysine residues to inhibit SARS-CoV-2 and other viruses

Researchers shed light on T-cell receptor activation in response to infection

Researchers shed light on T-cell receptor activation in response to infection

Using two different viruses to tackle tumors

Using two different viruses to tackle tumors

New tool enables study of SARS-CoV-2 mutant spectrum by ultrasequencing

New tool enables study of SARS-CoV-2 mutant spectrum by ultrasequencing

Study: SphK2 enzyme regulates immune cell responses during viral infection

Study: SphK2 enzyme regulates immune cell responses during viral infection

Researchers identify mechanisms leading to immune 'exhaustion' in severe viral infections

Researchers identify mechanisms leading to immune 'exhaustion' in severe viral infections

Discovery provides a potential target for infectious diseases immunotherapy

Discovery provides a potential target for infectious diseases immunotherapy

Rigidity of tissues drives immune system activity, UCLA study finds

Rigidity of tissues drives immune system activity, UCLA study finds

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