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Disabling survival pathways could be a promising strategy for brain tumor treatment

When you disable the brakes on a race car, it quickly crashes. Dr. Barak Rotblat wants to do something similar to brain cancer cells.

20 May 2024

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

Bimodal drug that successfully cures obesity, hyperglycemia, and dyslipidemia in mouse models.

20 May 2024

Insilico and NVIDIA unveil new LLM transformer for solving biological and chemical tasks

In a new paper, researchers from clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine ("Insilico"), in collaboration with NVIDIA, present a new large language model (LLM) transformer for solving biological and chemical tasks called nach0.

20 May 2024

Breakthrough ATP sensor sheds light on cellular energy dynamics

A molecule called adenosine triphosphate (ATP) is the basic unit of biochemical energy that fuels the activities of all cells.

17 May 2024

AlphaFold2 can be an effective tool in structure-based drug discovery

One of the most consequential advances in artificial intelligence isn't an eerily conversational chatbot-;it's a new way to unpack the unique 3D structures of proteins.

17 May 2024

Vaccine candidate spurs elusive type of broadly neutralizing HIV antibodies

An HIV vaccine candidate developed at the Duke Human Vaccine Institute triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.

17 May 2024

POSTECH and ImmunoBiome make significant breakthrough in the fight against cancer

A team of POSTECH and ImmunoBiome has made a significant breakthrough in the fight against cancer. Their research, published in the May issue of Nature Immunology (Volume 25, pages790–801,2024), explores a dietary-derived bacterial strain, IMB001.

17 May 2024

Johns Hopkins researchers identify key electrical activity behind congenital night blindness

In what they believe is a solution to a 30-year biological mystery, neuroscientists at Johns Hopkins Medicine say they have used genetically engineered mice to address how one mutation in the gene for the light-sensing protein rhodopsin results in congenital stationary night blindness.

17 May 2024

Study identifies key gluten peptide triggering leaky gut in celiac patients

Today is International Celiac Day. Celiac disease is a chronic autoimmune condition that occurs in around one per cent of the world's population.

17 May 2024

Reviving a rejected drug: New selective antibiotic shows promise

Twenty years ago, a drug candidate was rejected due to its side effects. Researchers have now figured out how to potentially make a successor molecule more selective.

17 May 2024

SMART researchers identify key mechanism behind artemisinin resistance in malaria

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, in collaboration with Massachusetts Institute of Technology (MIT), Columbia University Irving Medical Center (CUIMC), and Nanyang Technological University, Singapore (NTU Singapore), have discovered a link between malaria parasites' ability to develop resistance to antimalarial drugs – specifically artemisinin (ART) – through a cellular process called transfer Ribonucleic acid (tRNA) modification.

16 May 2024

Researchers develop pathoblockers to combat bacterial pneumonia toxins

In most cases, antibiotics are a reliable form of protection against bacterial infections. They have saved billions of human lives since their introduction.

16 May 2024

New therapy shows greater weight loss in mice by targeting brain's appetite center

A groundbreaking paper in Nature describes a promising new therapy for obesity that leads to greater weight loss in mice than existing medications.

16 May 2024

Sensing a Healthier Future with Sustainable Nanomaterials and Biosensors

In this interview conducted at Pittcon 2024 in San Diego, we spoke to this year's Keynote Speaker Professor Omowunmi (Wunmi) Sadik about how sustainable nanomaterials are transforming human health.

From Pittcon 16 May 2024

Unraveling the link between HLA genes and drug eruptions

Although medications can often help patients find a cure or respite from their condition, millions of people worldwide suffer from unpredictable drug toxicities every year.

15 May 2024

Study identifies a new biomarker for Alzheimer's disease in asymptomatic stages

A recent study led by the Molecular and Cellular Neurobiotechnology group at the Institute for Bioengineering of Catalonia (IBEC) and the University of Barcelona has identified a new biomarker for Alzheimer's disease in asymptomatic stages of the disease.

15 May 2024

Optibrium partners with FMC Corporation to transform agrochemical discovery

Optibrium, a leading developer of software and AI solutions for drug discovery, has signed a license agreement for its AI-powered discovery platform, Cerella™, with FMC Corporation (FMC), a global leader in crop protection.

From Optibrium Ltd. 15 May 2024

Metabolomics study finds biomarkers predicting autism in newborns

A study in Communications Biology utilized metabolomics in newborns to identify markers that might predict autism spectrum disorder (ASD), finding distinct metabolic profiles in children with ASD compared to typically developing children.

14 May 2024

Study proposes a novel therapeutic avenue for tackling EHF-induced cholangiocarcinogenesis

This study is led by Dr. Yiming Luo (Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology) and Professor. Huifang Liang (Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology).

14 May 2024

Zika virus-specific synthetic molecule can differentiate between prior infections with different flaviviruses

A newly discovered Zika virus-specific synthetic molecule is capable of differentiating Zika-immune patient samples from samples of patients previously infected with the related dengue virus.

14 May 2024

Molecule News and Research

Disabling survival pathways could be a promising strategy for brain tumor treatment

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

Insilico and NVIDIA unveil new LLM transformer for solving biological and chemical tasks

Breakthrough ATP sensor sheds light on cellular energy dynamics

AlphaFold2 can be an effective tool in structure-based drug discovery

Vaccine candidate spurs elusive type of broadly neutralizing HIV antibodies

POSTECH and ImmunoBiome make significant breakthrough in the fight against cancer

Johns Hopkins researchers identify key electrical activity behind congenital night blindness

Study identifies key gluten peptide triggering leaky gut in celiac patients

Reviving a rejected drug: New selective antibiotic shows promise

SMART researchers identify key mechanism behind artemisinin resistance in malaria

Researchers develop pathoblockers to combat bacterial pneumonia toxins

New therapy shows greater weight loss in mice by targeting brain's appetite center

Sensing a Healthier Future with Sustainable Nanomaterials and Biosensors

Unraveling the link between HLA genes and drug eruptions

Study identifies a new biomarker for Alzheimer's disease in asymptomatic stages

Optibrium partners with FMC Corporation to transform agrochemical discovery

Metabolomics study finds biomarkers predicting autism in newborns

Study proposes a novel therapeutic avenue for tackling EHF-induced cholangiocarcinogenesis

Zika virus-specific synthetic molecule can differentiate between prior infections with different flaviviruses

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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