Therapeutics News and Research

RSS

Disabling survival pathways could be a promising strategy for brain tumor treatment

When you disable the brakes on a race car, it quickly crashes. Dr. Barak Rotblat wants to do something similar to brain cancer cells.

20 May 2024

Columbia researchers link ferroptosis to COVID-19 lung disease

In some severe cases of COVID-19, the lungs undergo extreme damage, resulting in a range of life-threatening conditions like pneumonia, inflammation, and acute respiratory distress syndrome.

20 May 2024

Intracellular protein delivery with HyNT stamp system: A leap forward in cancer therapy

The intracellular delivery of proteins is an important technique for unveiling the cellular functions, protein complex structure, and therapeutics. However, the conventional delivery methods have several limitations.

20 May 2024

Non-viral gene therapy offers hope for chronic low back pain sufferers

A novel non-viral gene therapy for discogenic back pain (DBP).

20 May 2024

Cancer researchers urged to embrace AI for groundbreaking insights and efficiency

A review in Nature Reviews Cancer emphasizes the necessity for cancer researchers to understand AI's potentials and limitations, detailing its applications and challenges in cancer research to aid non-computational biologists.

20 May 2024

Immune checkpoint protein VISTA can directly turn off T-cells during immunotherapy, study finds

A Cleveland Clinic-led team of scientists and physicians have discovered that the immune checkpoint protein VISTA can directly turn off tumor-fighting T-cells during immunotherapy and resist treatment.

17 May 2024

Varenicline shows promise in first U.S. trial for e-cigarette cessation

The first U.S. trial of varenicline for e-cigarette cessation shows promising results and warrants larger-scale trials, the researchers say.

17 May 2024

Breakthrough imaging technique uncovers detailed scleral patterns in myopic eyes

Eye diseases are extremely prevalent worldwide, with recent estimates suggesting that one-third of the global population suffers from some type of vision impairment.

17 May 2024

Boosting mitochondrial health can reverse protein clumping in aging and Alzheimer's

It has long been known that a hallmark of Alzheimer's disease, and most other neurodegenerative diseases, is the clumping together of insoluble protein aggregates in the brain.

16 May 2024

Novel gene-delivery vehicle shows promise for treating brain disorders

In an important step toward more effective gene therapies for brain diseases, researchers from the Broad Institute of MIT and Harvard have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein.

16 May 2024

Genes and age reveal new insights into cognitive variability, study finds

Study examines the effects of specific genes and age on cognition, revealing potential for creating genotype- and cognition-stratified cohorts for future research.

16 May 2024

SMART researchers identify key mechanism behind artemisinin resistance in malaria

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, in collaboration with Massachusetts Institute of Technology (MIT), Columbia University Irving Medical Center (CUIMC), and Nanyang Technological University, Singapore (NTU Singapore), have discovered a link between malaria parasites' ability to develop resistance to antimalarial drugs – specifically artemisinin (ART) – through a cellular process called transfer Ribonucleic acid (tRNA) modification.

16 May 2024

New therapy shows greater weight loss in mice by targeting brain's appetite center

A groundbreaking paper in Nature describes a promising new therapy for obesity that leads to greater weight loss in mice than existing medications.

16 May 2024

RedShiftBio launches Aurora TX: Revolutionizing RNA and protein analysis with ultra-sensitive microfluidic modulation spectroscopy and thermal ramping capability

RedShiftBio, a leader in innovative biophysical characterization and bioprocess analytical solutions, proudly announces the launch of Aurora TX at The Protein & Antibody Engineering Summit (PEGS), kicking off on May 13, 2024, in Boston, MA. Aurora TX is the company's latest, most advanced instrument featuring ground-breaking MMS technology, and sets a new standard in biomolecular analysis by providing ultra-sensitive, ultra-precise measurements of biomolecule structure and stability, now enhanced with the addition of thermal ramping capability.

From RedShiftBio 16 May 2024

Study reveals association between ribosomal DNA copy number and disease risk

Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses.

15 May 2024

St. Jude researchers unveil mechanisms to block PXR and enhance drug potency

Deaths from cancer or infections can occur when available treatments are ineffective. Once turned on, pregnane X receptor (PXR) activates the expression of genes encoding enzymes that metabolize external chemicals, including drugs.

14 May 2024

Experts advocate for terminology change in brain injury research

A new editorial published this May in the British Journal of Sports Medicine by experts from Spaulding Rehabilitation, Boston University, Mayo Clinic, and the Concussion Legacy Foundation, argues that the term "subconcussion" is a dangerous misnomer that should be retired.

14 May 2024

Therapeutics News and Research

Disabling survival pathways could be a promising strategy for brain tumor treatment

Columbia researchers link ferroptosis to COVID-19 lung disease

Intracellular protein delivery with HyNT stamp system: A leap forward in cancer therapy

Non-viral gene therapy offers hope for chronic low back pain sufferers

Cancer researchers urged to embrace AI for groundbreaking insights and efficiency

Immune checkpoint protein VISTA can directly turn off T-cells during immunotherapy, study finds

Varenicline shows promise in first U.S. trial for e-cigarette cessation

Breakthrough imaging technique uncovers detailed scleral patterns in myopic eyes

Boosting mitochondrial health can reverse protein clumping in aging and Alzheimer's

Novel gene-delivery vehicle shows promise for treating brain disorders

Genes and age reveal new insights into cognitive variability, study finds

SMART researchers identify key mechanism behind artemisinin resistance in malaria

New therapy shows greater weight loss in mice by targeting brain's appetite center

RedShiftBio launches Aurora TX: Revolutionizing RNA and protein analysis with ultra-sensitive microfluidic modulation spectroscopy and thermal ramping capability

Study reveals association between ribosomal DNA copy number and disease risk

St. Jude researchers unveil mechanisms to block PXR and enhance drug potency

Experts advocate for terminology change in brain injury research

Unraveling the genetic connection between IBD and Parkinson's disease

Western diet linked to chronic diseases by gut microbiota disruption

Aficamten shows promise in enhancing exercise capacity in patients with hypertrophic cardiomyopathy

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest News