Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Microglia are specialized immune cells in the brain. While they normally protect our brains, they can also contribute to neurodegenerative diseases such as Alzheimer's.

27 Mar 2024

Multiomic approach boosts disease prediction accuracy beyond traditional methods

Study highlights the significant enhancement in predicting common diseases like heart disease, diabetes, Alzheimer's, and prostate cancer by integrating polygenic risk scores (PRSs) and gut microbiome scores with conventional risk factors, showcasing the potential of multiomic approaches in personalized medicine.

26 Mar 2024

Study identifies brain energy metabolism dysfunction in neuropsychiatric disorders

A global collaborative research group comprising 131 researchers from 105 laboratories across seven countries announces a groundbreaking research paper submitted to eLife.

26 Mar 2024

Researchers identify new potential target for the treatment of Alzheimer's disease

Researchers at the University of Leeds and Lancaster University in the UK have identified a new potential target for the treatment of Alzheimer's disease – PDE4B.

26 Mar 2024

Mediterranean diet linked to lower dementia risk, finds extensive review

Meta-analysis reveals a positive link between adherence to the Mediterranean diet and a reduced risk of dementia, particularly Alzheimer's disease, among older adults, highlighting the diet's potential as a modifiable risk factor in dementia prevention strategies.

26 Mar 2024

Study adds new evidence on the link between Type 2 diabetes and Alzheimer's disease

New research conducted in mice offers insights into what's going on at the molecular level that could cause people with diabetes to develop Alzheimer's disease.

25 Mar 2024

Reciprocated care in Alzheimer's couples enhances mutual well-being

In cases of Alzheimer's disease, it's common for a spouse to take on the role of caregiver. Research led by the University of California, Davis, suggests that patients can also support their caretakers, and that reciprocated care has mutual benefits.

22 Mar 2024

New drug inhibitors target protein linked to Alzheimer's and heart disease

The health impacts of a complex protein that plays a major role in the development of Alzheimer's disease and heart conditions can be lessened by three kinds of drug inhibitors, according to scientists at the University of Colorado Anschutz Medical Campus.

22 Mar 2024

Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024

Aging linked to length of genes, study suggests

Aging may be less about specific "aging genes" and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers in an opinion piece publishing March 21 in the journal Trends in Genetics.

22 Mar 2024

Long genes linked to faster biological aging

What causes our body to age? Four complementary studies, including one from Northwestern Medicine, have come to the same conclusion: long genes.

21 Mar 2024

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer's and other diseases.

21 Mar 2024

Study pinpoints several genetic variants contributing to Alzheimer's disease

Identifying genetic variants and the role they play in predisposing people to Alzheimer's disease can help researchers better understand how to treat the neurodegenerative condition for which there is currently no cure.

21 Mar 2024

Hearing loss linked to accelerated Alzheimer's progression via GDF1 pathway

Study unveils the GDF1 signaling pathway's role in mitigating the adverse effects of hearing loss on Alzheimer's disease, spotlighting potential avenues for therapeutic development.

20 Mar 2024

Study shows barriers to dementia diagnosis based on race, ethnicity, and location

Getting dementia diagnosed can be a long and difficult process for anyone, but some may face additional challenges based on race or ethnicity and where they live, according to a study led by Washington State University researchers.

20 Mar 2024

Unveiling Alzheimer's disease mechanisms through brain network analysis

In a study published in Psychoradiology on January 11, 2024, researchers from the University of Texas at Arlington and the University of Georgia have systematically summarized studies on brain networks within the context of AD, critically analyzed the strengths and weaknesses of existing methodologies, and offered novel perspectives and insights, intending to serve as inspiration for future research.

19 Mar 2024

Ketogenic diet delays the early stages of Alzheimer's-related memory loss in mice

A new study from researchers at the University of California, Davis, shows a ketogenic diet significantly delays the early stages of Alzheimer's-related memory loss in mice.

19 Mar 2024

More than 3 billion people worldwide lived with a neurological condition in 2021, new study reports

Researchers estimated global, regional, and national health loss due to 37 nervous system conditions and their associated risk factors from 1990 to 2021.

19 Mar 2024

New compounds show potential to mimic benefits of exercise

Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise.

18 Mar 2024

Global health burden of neurological conditions is much greater than previously understood, study reveals

Globally, the number of people living with, or dying from, neurological conditions such as stroke, Alzheimer's disease and other dementias, and meningitis has risen substantially over the past 30 years due to the growth and ageing of the global population as well as increased exposure to environmental, metabolic, and lifestyle risk factors.

18 Mar 2024

Alzheimer's Disease News and Research

Further Reading

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Multiomic approach boosts disease prediction accuracy beyond traditional methods

Study identifies brain energy metabolism dysfunction in neuropsychiatric disorders

Researchers identify new potential target for the treatment of Alzheimer's disease

Mediterranean diet linked to lower dementia risk, finds extensive review

Study adds new evidence on the link between Type 2 diabetes and Alzheimer's disease

Reciprocated care in Alzheimer's couples enhances mutual well-being

New drug inhibitors target protein linked to Alzheimer's and heart disease

Study shows cellular, molecular overlaps in ALS and FTLD

Aging linked to length of genes, study suggests

Long genes linked to faster biological aging

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Study pinpoints several genetic variants contributing to Alzheimer's disease

Hearing loss linked to accelerated Alzheimer's progression via GDF1 pathway

Study shows barriers to dementia diagnosis based on race, ethnicity, and location

Unveiling Alzheimer's disease mechanisms through brain network analysis

Ketogenic diet delays the early stages of Alzheimer's-related memory loss in mice

More than 3 billion people worldwide lived with a neurological condition in 2021, new study reports

New compounds show potential to mimic benefits of exercise

Global health burden of neurological conditions is much greater than previously understood, study reveals

Aneuro: A Year of Neuroscience in Review eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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