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Researchers enhance CAR-T cells to target solid tumors

Researchers at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have shown that a breakthrough therapy for treating blood cancers can be adapted to treat solid tumors-;an advance that could transform cancer treatment.

8 May 2024

New Quartet nanocage vaccine shows promise against coronavirus variants

Researchers have developed a novel vaccination approach using Quartet nanocages that display receptor-binding domains (RBDs) from different sarbecoviruses, showing enhanced immune responses and potential protection against diverse coronavirus strains including SARS-CoV-2 and its variants.

8 May 2024

AI-driven model identifies potent cancer-killing immune cells for personalized immunotherapy

Using artificial intelligence, Ludwig Cancer Research scientists have developed a powerful predictive model for identifying the most potent cancer killing immune cells for use in cancer immunotherapies.

7 May 2024

Bacterial fatty acid metabolite identified as key player in immune regulation

Gut microbiota or the population of microbial inhabitants in the intestine, plays a key role in digestion and maintenance of overall health.-

7 May 2024

New vaccine technology provides protection against broad range of coronaviruses in mice

Researchers have developed a new vaccine technology that has been shown in mice to provide protection against a broad range of coronaviruses with potential for future disease outbreaks - including ones we don't even know about.

6 May 2024

Durable lymph-node expansion improves vaccine responses against tumors

Each one of us has around 600 lymph nodes (LNs) – small, bean-shaped organs that house various types of blood cells and filter lymph fluid – scattered throughout our bodies.

6 May 2024

What is the association between post-diagnostic plant-based dietary patterns and the risk of prostate cancer progression?

The relationship between the risk of progression of prostate cancer and plant-based diet adherence.

6 May 2024

Novel vaccine approach targets AML and other blood cancers

Acute myeloid leukemia (AML) is a type of blood cancer that forms in the soft marrow of the bones, typically attacking cells that would otherwise form the key component of the body's immunodefense system, white blood cells.

3 May 2024

Study supports the consideration of 177Lu-PSMA-617 as new standard treatment for metastatic prostate cancer

In a follow-on analysis of results from the phase 3 PSMAfore study, clinical investigators from Dana-Farber and elsewhere found that clinical outcomes consistently favored 177Lu-PSMA-617 over a change from one androgen receptor pathway inhibitor (ARPI) to another, regardless of which ARPI patients received first.

3 May 2024

New vaccine approach shows promise in targeting less variable region of influenza virus

Duke researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that is less variable.

2 May 2024

Researchers unveil unique autoantibody profiles in rheumatoid arthritis patients

Patients with rheumatoid arthritis (RA) all have a unique and diverse set of antibodies that are involved in the development of the disease.

2 May 2024

UCL to co-lead Prostate Cancer UK's new £42m screening trial

UCL academics will co-lead Prostate Cancer UK's new £42m screening trial, which aims to find the best way to screen men for prostate cancer and double the number of lives saved.

2 May 2024

A gut bacteria could hold the key to universal blood, revolutionizing transfusion medicine

Study found that exoglycosidases from Akkermansia muciniphila effectively target blood group antigens, potentially converting A and B blood types to ABO-universal blood.

1 May 2024

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

30 Apr 2024

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

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30 Apr 2024

Study rethinks immune system strategies to boost vaccine effectiveness

A recent Cell journal review explores key immunological assumptions to enhance our understanding of vaccine design, autoimmune responses, and immune system pathology, aiming to refine intervention strategies and theoretical frameworks in immunology.

28 Apr 2024

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

The real-world safety and efficacy of sacituzumab govitecan (SG) against metastatic triple-negative breast cancer.

26 Apr 2024

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

A review in Nature Reviews Nephrology presents the association between immune cells and the development of hypertension, suggesting potential new therapeutic targets to mitigate the disease by managing inflammation.

26 Apr 2024

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Driven by the overuse of antimicrobials, pathogens are quickly building up resistances to once-successful treatments.

24 Apr 2024

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

24 Apr 2024

Antigen News and Research

Researchers enhance CAR-T cells to target solid tumors

New Quartet nanocage vaccine shows promise against coronavirus variants

AI-driven model identifies potent cancer-killing immune cells for personalized immunotherapy

Bacterial fatty acid metabolite identified as key player in immune regulation

New vaccine technology provides protection against broad range of coronaviruses in mice

Durable lymph-node expansion improves vaccine responses against tumors

What is the association between post-diagnostic plant-based dietary patterns and the risk of prostate cancer progression?

Novel vaccine approach targets AML and other blood cancers

Study supports the consideration of 177Lu-PSMA-617 as new standard treatment for metastatic prostate cancer

New vaccine approach shows promise in targeting less variable region of influenza virus

Researchers unveil unique autoantibody profiles in rheumatoid arthritis patients

UCL to co-lead Prostate Cancer UK's new £42m screening trial

A gut bacteria could hold the key to universal blood, revolutionizing transfusion medicine

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

Study rethinks immune system strategies to boost vaccine effectiveness

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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