Appendicitis News and Research

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Appendicitis is a painful swelling and infection of the appendix. The appendix is a fingerlike pouch attached to the large intestine and located in the lower right area of the abdomen. Scientists are not sure what the appendix does, if anything, but removing it does not appear to affect a person’s health. The inside of the appendix is called the appendiceal lumen. Mucus created by the appendix travels through the appendiceal lumen and empties into the large intestine.

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

20 Nov 2020

$Are bone fractures more common in non-meat eaters?$

Are bone fractures more common in non-meat eaters?

A new study has found that in comparison with people who eat meat, vegans, vegetarians, and pescatarians may be at a higher risk of hip fractures.

20 Nov 2020

Hospitalized? You can still vote in most parts of the country

Johnathon Talamantes, of South-Central Los Angeles, broke his hip in a car accident on Oct. 22 and underwent surgery five days later at a public hospital near downtown.

2 Nov 2020

Antibiotics might be a feasible treatment option for appendicitis, shows study

Henry Ford Health System surgeons involved in the study say patients should choose the best option in consultation with their physician.

6 Oct 2020

CODA trial shows antibiotics may be a good choice for certain patients with appendicitis

Antibiotics may be a good choice for some, but not all, patients with appendicitis, according to results from the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) Trial reported today in the New England Journal of Medicine.

6 Oct 2020

Antibiotic treatment is as good as appendectomy for a majority of adults with appendicitis

Seven of 10 adults with appendicitis can safely avoid surgical removal of their appendix (appendectomy) for at least several months by receiving a course of antibiotics, according to early results of a U.S. study that is the largest to compare use of these drugs alone versus an operation for appendicitis treatment.

6 Oct 2020

Study compares antibiotic therapy with surgery in patients with appendicitis

Results of a first-of-its-kind clinical trial shed light on when antibiotics instead of surgery might be the better choice for treating appendicitis in some patients, according to researchers with The University of Texas Health Science Center at Houston, who led the Houston trial sites.

5 Oct 2020

Pregnant women who underwent surgery for complicated appendicitis have significantly better outcomes

Pregnant women who underwent immediate surgery to treat a ruptured or abscessed appendix and their fetuses had significantly better outcomes than those whose condition was managed without an operation.

5 Oct 2020

CT scans used at a higher rate in children with cognitive impairment to diagnose appendicitis

Computed tomography (CT) is used at a higher rate than ultrasound in children with developmental and cognitive impairments to diagnose appendicitis, even though CT scans increase radiation risk in smaller bodies.

21 Aug 2020

Antibiotics alone can effectively treat children with uncomplicated appendicitis

Appendicitis is the most common cause for emergency abdominal surgery in childhood, affecting 80,000 children in the United States each year, but nonoperative treatment options are viable.

27 Jul 2020

Emergent hospitalizations have declined during early phase of COVID-19, shows study

Early reports have shown the COVID-19 pandemic has resulted in a decline in patients seeking outpatient medical care.

24 Jul 2020

Why doctors keep monitoring kids who recover from mysterious COVID-linked illness

Israel Shippy doesn’t remember much about having COVID-19 — or the unusual auto-immune disease it triggered — other than being groggy and uncomfortable for a bunch of days. He’s a 5-year-old, and would much rather talk about cartoons, or the ideas for inventions that constantly pop into his head.

16 Jul 2020

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children

The ongoing COVID-19 pandemic has cost hundreds of thousands of human lives, besides more than 11 million cases. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the disease was initially thought to be more severe in the elderly and those with pre-existing medical conditions. However, it started to manifest in children after the peak of the first wave.

7 Jul 2020

COVID catch-22: They got a big ER bill because hospitals couldn’t test for virus

Fresh off a Caribbean cruise in early March, John Campbell developed a cough and fever of 104 degrees. He went to his primary care physician and got a flu test, which came up negative.

7 Jul 2020

SARS-CoV-2 can replicate in human pediatric gastric organoids

A diverse research group from the United Kingdom, Italy, China, and Australia established a first expandable human gastric organoid culture across fetal developmental stages, supporting the hypothesis that fetal tissue seems to be much less susceptible to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection – especially in the early stages of development.

25 Jun 2020

Hormone involved in obesity could increase the risk for sepsis infection

A group of scientists from Instituto Gulbenkian de Ciência, led by Luís Moita, discovered that a hormone that has been pointed out as a treatment for obesity reduces the resistance to infection caused by bacteria and is a risk factor for sepsis.

22 Jun 2020

Children with COVID-19 presenting with sudden severe lung disease

Even as the COVID-19 pandemic continues to seek out new victims, puzzling new presentations are further confusing the situation. A new study published online in The Lancet Rheumatology in May 2020 reports a case of severe COVID-19 in a child who rapidly developed acute respiratory distress symptoms without prior respiratory symptoms. This case should alert clinicians to consider this diagnosis in children as well.

24 May 2020

Kawasaki disease outbreak in children with COVID-19

The ongoing COVID-19 pandemic has marched its way to almost all parts of the world, with hundreds of thousands of deaths and over 4.5 million cases as of May 15, 2020. One saving grace has been the apparent sparing of children, though the mortality in older people is quite high.

17 May 2020

Accurate diagnosis of appendicitis in the emergency department may be more challenging

While symptoms of appendicitis may be common, a new study suggests that accurately diagnosing the condition in the emergency department may be more challenging.

16 Mar 2020

Patient satisfaction and quality of life similar across all appendicitis treatments

A new study published in the journal JAMA Surgery in February 2020 shows that patients with acute appendicitis that were successfully treated either by antibiotics or by appendectomy had identical satisfaction with their treatment and identical quality of life over the long term. The patients who were first treated conservatively and then had appendectomy had lower satisfaction rates.

19 Feb 2020

Appendicitis News and Research

Further Reading

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

Are bone fractures more common in non-meat eaters?

Hospitalized? You can still vote in most parts of the country

Antibiotics might be a feasible treatment option for appendicitis, shows study

CODA trial shows antibiotics may be a good choice for certain patients with appendicitis

Antibiotic treatment is as good as appendectomy for a majority of adults with appendicitis

Study compares antibiotic therapy with surgery in patients with appendicitis

Pregnant women who underwent surgery for complicated appendicitis have significantly better outcomes

CT scans used at a higher rate in children with cognitive impairment to diagnose appendicitis

Antibiotics alone can effectively treat children with uncomplicated appendicitis

Emergent hospitalizations have declined during early phase of COVID-19, shows study

Why doctors keep monitoring kids who recover from mysterious COVID-linked illness

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children

COVID catch-22: They got a big ER bill because hospitals couldn’t test for virus

SARS-CoV-2 can replicate in human pediatric gastric organoids

Hormone involved in obesity could increase the risk for sepsis infection

Children with COVID-19 presenting with sudden severe lung disease

Kawasaki disease outbreak in children with COVID-19

Accurate diagnosis of appendicitis in the emergency department may be more challenging

Patient satisfaction and quality of life similar across all appendicitis treatments

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