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Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Researchers developed bispecific antibodies targeting both the N-terminal and receptor binding domains of SARS-CoV-2, demonstrating significant neutralization across various Omicron variants, suggesting potential for new COVID-19 treatments.

9 May 2024

Unraveling the complex pathology of gastric cancer: TP53 loss and extrinsic risk factors

GC ranks as the fifth most common and fourth deadliest cancer worldwide, presenting significant health challenges, particularly in China where it is most prevalent and accounts for nearly half of newly diagnosed and death cases.

7 May 2024

Advancing equity in cancer care: Lessons from NCI-DCCs' community outreach and engagement initiatives

Investigators at Dana-Farber Cancer Institute have examined the historical evolution of Community Outreach and Engagement initiatives at both the National Cancer Institute (NCI) and National Cancer Institute-Designated Cancer Centers (NCI-DCCs).

6 May 2024

Researchers review current evidence on Candida auris, an emerging multidrug-resistant yeast

Researchers discuss current evidence on Candida auris, an emerging multidrug-resistant yeast.

6 May 2024

Bird flu is bad for poultry and dairy cows. It’s not a dire threat for most of us — yet.

Headlines are flying after the Department of Agriculture confirmed that the H5N1 bird flu virus has infected dairy cows around the country.

3 May 2024

Research highlights the link between mitochondrial calcium transport and autophagy

An article published in The Faseb Journal describes a Brazilian study analyzing the correlation between two key energy metabolism regulation processes: the absorption and release of calcium ions by mitochondria, the organelles that generate energy for cells; and autophagy induced by calorie restriction. Autophagy occurs when cells break down and reuse their own cytoplasm.

2 May 2024

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs (genetic material that instructs the body on how to make proteins), are degraded.

1 May 2024

ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

Proteins are the workhorses of life. Organisms use them as building blocks, receptors, processors, couriers and catalysts.

30 Apr 2024

Updated vaccine provides strong immune response against previous and emerging SARS-CoV-2 variants

New research using live SARS-CoV-2 virus reveals an updated vaccine provides a strong immune response against previous strains and emerging variants.

29 Apr 2024

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were found vulnerable during the COVID-19 pandemic.

29 Apr 2024

New study reveals global risk distribution of visceral leishmaniasis

Announcing a new article publication for Zoonoses journal. Visceral leishmaniasis (VL) is a vector-borne disease posing increasing public health concerns.

28 Apr 2024

Yeast study reveals evolutionary history of iron uptake mechanisms

Competition and cooperation are fundamental forces that govern the evolutionary and ecological dynamics among species.

25 Apr 2024

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

The Covid-19 pandemic turned the world upside down. In fighting it, one of our most important weapons was genomic surveillance, based on whole genome sequencing, which collects all the genetic data of a given microorganism.

25 Apr 2024

Novel lab-grown mini-colons can accurately mimic the development of colorectal tumors

In a breakthrough for cancer research, scientists at EPFL have created lab-grown mini-colons that can accurately mimic the development of colorectal tumors, offering a powerful new tool for studying and testing treatments for the disease.

24 Apr 2024

Timelapse breakthrough: Scientists capture secrets of early embryonic cell division

The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis is well-studied in the so-called somatic cells – the cells that have a specialized function, like skin and muscle cells – they remain elusive in the first cells of our bodies, the embryonic cells.

24 Apr 2024

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Study assesses global discrepancies in COVID-19 management guidelines across WHO member states, revealing that many national guidelines do not fully align with WHO recommendations, especially in lower-resource countries.

23 Apr 2024

Analysis finds significant variations in national COVID-19 treatment recommendations

National clinical guidelines for the treatment of COVID-19 vary significantly around the world, with under-resourced countries the most likely to diverge from gold standard (World Health Organization; WHO) treatment recommendations, finds a comparative analysis published in the open access journal BMJ Global Health.

23 Apr 2024

Study discovers hidden mechanism behind rapid COVID variants

The SARS-CoV-2 virus that causes COVID has the unsettling ability of often generating variants of itself. Other viruses also mutate, but as SARS-CoV-2 quickly spread throughout the entire human population during the pandemic, killing millions, the virus' dynamic evolution posed a serious problem: it repeatedly challenged our bodies' immune response fighting the virus and hindered the process of getting updated vaccines ready.

23 Apr 2024

Ophthalmological method can be used to monitor neurodegeneration in Parkinson's patients

A study by the University of the Basque Country (UPV/EHU) and Biobizkaia proposes using an available, simple, non-invasive tool to monitor this neurodegeneration.

22 Apr 2024

UC Riverside nematologist receives NIH award to study parasite-host interactions

To study how parasites evolve to break the defenses of their hosts, the National Institutes of Health has granted UC Riverside nematologist Simon "Niels" Groen a $1.9 million Outstanding Investigator Award.

18 Apr 2024

Evolution News and Research

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Unraveling the complex pathology of gastric cancer: TP53 loss and extrinsic risk factors

Advancing equity in cancer care: Lessons from NCI-DCCs' community outreach and engagement initiatives

Researchers review current evidence on Candida auris, an emerging multidrug-resistant yeast

Bird flu is bad for poultry and dairy cows. It’s not a dire threat for most of us — yet.

Research highlights the link between mitochondrial calcium transport and autophagy

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

Updated vaccine provides strong immune response against previous and emerging SARS-CoV-2 variants

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

New study reveals global risk distribution of visceral leishmaniasis

Yeast study reveals evolutionary history of iron uptake mechanisms

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

Novel lab-grown mini-colons can accurately mimic the development of colorectal tumors

Timelapse breakthrough: Scientists capture secrets of early embryonic cell division

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Analysis finds significant variations in national COVID-19 treatment recommendations

Study discovers hidden mechanism behind rapid COVID variants

Ophthalmological method can be used to monitor neurodegeneration in Parkinson's patients

UC Riverside nematologist receives NIH award to study parasite-host interactions

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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