Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

8 Apr 2024

NeuM technology revolutionizes neuron labeling for neurodegenerative disease research

Alzheimer's disease and Parkinson's disease, along with stroke, are among the top three neurodegenerative disorders, characterized by the malfunction and progressive degeneration of neurons, the nerve cells.

8 Apr 2024

UCLA study finds pre-surgery immunotherapy safe for pancreatic cancer patients

A pilot study led by UCLA Health Jonsson Comprehensive Cancer Center investigators suggests that for people with borderline resectable pancreatic cancer, administrating an immunotherapy drug in combination with chemotherapy before surgery is safe and may improve long-term outcomes.

5 Apr 2024

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

Understanding the mechanisms behind cystic fibrosis infections

Cystic fibrosis is a genetic disease that causes serious and sometimes fatal respiratory and digestive disorders.

4 Apr 2024

Muscles in microgravity: Spaceflight duration impacts muscle protein stress markers

Study explores the differential effects of short and long-duration space missions on muscle protein nitrosylation in astronauts, indicating adaptations and potential impairments in muscle function due to microgravity, and highlights the role of inflight exercise in mitigating some negative effects on muscle health.

3 Apr 2024

Computational tools predict protein-RNA interactions

Researchers from Aarhus University and the Italian Institute of Technology have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes.

3 Apr 2024

How minerals influence women's fertility and menstrual health

Research reviews the essential role of minerals like zinc, selenium, and iron in supporting female reproductive health, emphasizing their impact on hormone regulation, ovulation, and endometrial health.

3 Apr 2024

Balanced diet linked to better brain health and cognition, large-scale study shows

Study utilizing the UK Biobank data identifies four dietary patterns, revealing the balanced diet subtype promotes superior cognitive functions and mental health outcomes compared to starch-free, vegetarian, or high-protein-low-fiber diets.

3 Apr 2024

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

Study demonstrated that selectively reducing myeloid-biased hematopoietic stem cells (my-HSCs) in aged mice rejuvenated the immune system, enhanced lymphopoiesis, reduced inflammation, and improved responses to viral infection, highlighting a potential strategy for countering age-related immune decline.

31 Mar 2024

DNA repair process key to memory formation, study finds

Study reveals that learning triggers a series of molecular events including DNA damage and repair in hippocampal neurons, mediated by TLR9, crucial for memory formation.

31 Mar 2024

Researchers decode the evolutionary pathway of regulatory proteins

New research from the University of Wisconsin–Madison decodes the evolutionary pathway of regulatory proteins, the molecules that help control gene expression.

29 Mar 2024

Uncovering gender-specific genetic alterations in cancer

Recent research spearheaded by Chunmei Cui at the State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, China, casts a new light on the nuanced interplay between gender and cancer, uncovering significant sex-specific disparities in copy number alterations (CNA) across various cancer types.

29 Mar 2024

Unraveling gene regulation's role in pulmonary fibrosis

Regulators of gene expression are thought to play an outsized role in disorders from cancers to heart disease. But how exactly do variations in gene regulation translate into a disease's biology?

28 Mar 2024

Predicting treatment response in common blood cancer with DNA methylation profiling

A recent study led by Dr. Manel Esteller, Director of the Josep Carreras Institute, shows how DNA methylation profiling in a common type of blood cancer, myelodysplastic syndrome, predicts whether the patient will respond to treatment.

28 Mar 2024

Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast cancer, an aggressive form of breast cancer.

27 Mar 2024

Gene Expression News and Research

Further Reading

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

NeuM technology revolutionizes neuron labeling for neurodegenerative disease research

UCLA study finds pre-surgery immunotherapy safe for pancreatic cancer patients

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Understanding the mechanisms behind cystic fibrosis infections

Muscles in microgravity: Spaceflight duration impacts muscle protein stress markers

Computational tools predict protein-RNA interactions

How minerals influence women's fertility and menstrual health

Balanced diet linked to better brain health and cognition, large-scale study shows

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

DNA repair process key to memory formation, study finds

Researchers decode the evolutionary pathway of regulatory proteins

Uncovering gender-specific genetic alterations in cancer

Unraveling gene regulation's role in pulmonary fibrosis

Predicting treatment response in common blood cancer with DNA methylation profiling

Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

Drug combination could hold new promise for treating colorectal cancers and other solid tumors

New treatment paradigm focuses on reverting cancer cells to normal state

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

New method predicts sepsis and organ failure in children

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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