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Researchers discover a highly potent biomarker for clinical response to CAR-T cell therapy

A MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequisites for optimal use of this novel therapy for lymphoma treatment.

9 Jan 2023

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

A patient with relapsed T cell leukemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

12 Dec 2022

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

Patients taking efgartigimod, a drug being studied for use to treat chronic primary immune thrombocytopenia (ITP), exhibited a significantly greater improvement in platelet counts which are essential to clotting and stopping bleeding, compared to those taking a placebo, according to results reported from the ADVANCE IV clinical trial, which was conducted globally, including at Georgetown University Medical Center.

12 Dec 2022

ASCOT trial pinpoints most efficient level of blood thinning treatment for hospitalized COVID-19 patients

The COVID-19 global pandemic remains a major public health challenge. ASCOT researchers aim to discover which treatments are most effective in patients hospitalized with COVID-19.

12 Dec 2022

HIV-positive people are protected by Covid vaccines

People infected with HIV who receive antiretroviral therapy form antibodies against Sars-Cov-2 after being vaccinated against Covid with mRNA vaccines.

9 Dec 2022

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

Mutations of BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 people respectively, significantly increase the risk of certain cancers such as ovarian, breast, pancreatic and prostate cancer.

28 Nov 2022

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

A third COVID-19 vaccine dose in this patients with blood cancers could enhance their antibody responses against SARS-CoV-2

21 Nov 2022

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

A collaborative study led by the University of Oxford as part of the UK's 100,000 Genomes Project, published in Nature Genetics today, has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukemia (CLL) and associated these with clinical outcomes.

16 Nov 2022

Researchers make first bone marrow 'organoids' to capture key features of human bone marrow

Scientists from Oxford University and the University of Birmingham have made the first bone marrow 'organoids' that capture the key features of human bone marrow.

15 Nov 2022

Research reveals why stem cell transplants are so successful in MS patients

Blood stem cell transplantation is a radical but highly effective therapy for multiple sclerosis. A study led by the University of Zurich has now examined in detail the way in which the treatment curbs the autoimmune disease and how the immune system regenerates afterwards.

10 Nov 2022

Study elucidates mechanism that is crucial for making hemophilia therapy effective

Hemophilia A is the most common severe form of hemophilia. It affects almost exclusively males. The disease can usually be treated well, but not for all sufferers.

27 Oct 2022

AI model could be used to enable more effective care for skin cancer patients

The artificial intelligence model could be utilized to enable more effective care for skin cancer patients and could lead to similar breakthroughs in the diagnosis and treatment of other cancers.

7 Oct 2022

Routine newborn screening for sickle cell disease urgently needed to save lives in Africa

More than 300,000 babies globally are born every year with sickle cell, a hereditary condition which causes red blood cells to become sickle-shaped.

5 Oct 2022

PhoreMost enters multi-project drug target discovery collaboration with Roche

PhoreMost to deploy its SITESEEKER platform to identify novel targets for Roche’s discovery programmes

From PhoreMost 6 Sep 2022

Review may lead to improvements in therapeutic options for preterm infants

One in two premature babies receives transfusions of red blood cells (RBC) due to anemia. There are no generally accepted clinical guidelines for the degree of anemia necessitating blood transfusions.

26 Jul 2022

Researchers explore disease severity post-infection with SARS-CoV-2 Omicron in hematologic patients

A new study has studied the clinical outcome and spectrum in 61 patients infected with the SARS-CoV-2 Omicron variant.

29 Jun 2022

Novel app can help doctors make better decisions for patients with leukemia.

Researchers at the University of Copenhagen and clinicians at Rigshospitalet have developed an app that can help doctors make better decisions for patients with leukemia.

24 Jun 2022

New combination of drugs effective against T-cell acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common cancer affecting children. The T-ALL form of leukemia that emerges from early T lineage cells has a poorer prognosis than B-lineage ALL. The prognosis for relapsed T-ALL is very poor and new therapies are sorely needed.

20 Jun 2022

AI tool allows clinicians to make optimal, personalized chemotherapy doses for patients

A team of researchers from National University of Singapore, in collaboration with clinicians from the National University Cancer Institute, Singapore which is part of the National University Health System (NUHS), has reported promising results in using CURATE.AI, an artificial intelligence (AI) tool that identifies and better allows clinicians to make optimal and personalized doses of chemotherapy for patients.

13 Jun 2022

Scientists unlock the cellular secrets of aging process

New research has uncovered how genetic changes that accumulate slowly in blood stem cells throughout life are likely to be responsible for the dramatic change in blood production after the age of 70.

1 Jun 2022

Haematology News and Research

Researchers discover a highly potent biomarker for clinical response to CAR-T cell therapy

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

ASCOT trial pinpoints most efficient level of blood thinning treatment for hospitalized COVID-19 patients

HIV-positive people are protected by Covid vaccines

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

Researchers make first bone marrow 'organoids' to capture key features of human bone marrow

Research reveals why stem cell transplants are so successful in MS patients

Study elucidates mechanism that is crucial for making hemophilia therapy effective

AI model could be used to enable more effective care for skin cancer patients

Routine newborn screening for sickle cell disease urgently needed to save lives in Africa

PhoreMost enters multi-project drug target discovery collaboration with Roche

Review may lead to improvements in therapeutic options for preterm infants

Researchers explore disease severity post-infection with SARS-CoV-2 Omicron in hematologic patients

Novel app can help doctors make better decisions for patients with leukemia.

New combination of drugs effective against T-cell acute lymphoblastic leukemia

AI tool allows clinicians to make optimal, personalized chemotherapy doses for patients

Scientists unlock the cellular secrets of aging process

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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