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Cryo-EM reveals TAF15 as potential treatment target for frontotemporal dementia

An international team of researchers including experts at the Indiana University School of Medicine has identified a protein found in the brains of people with frontotemporal dementia (FTD), discovering a new target for potential treatments for the disease.

7 Dec 2023

Twice daily electrical stimulation boosts brain plasticity and improves memory in Alzheimer's patients

Twice daily non-invasive electrical stimulation of the brain may boost mental processes (cognitive function) in people with Alzheimer's disease, suggest the results of a small clinical trial published online in the open access journal General Psychiatry.

6 Dec 2023

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

A group of authors critically evaluated and interpreted the evidence linking mitochondrial dysfunction and metabolic changes to the pathogenesis of Alzheimer's disease (AD).

5 Dec 2023

The effects of vitamin K on bone health

Existing scientific data on the effects of vitamin K (VK) on bone health and elucidated the underlying mechanisms.

30 Nov 2023

New signaling mechanism implicated in the development of ventricular fibrillation

A study led by Guadalupe Sabio and José Jalife at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid has identified a new signaling mechanism implicated in the development of ventricular fibrillation, a type of arrhythmia, or irregular heartbeat.

27 Nov 2023

Numbing agent lidocaine may have cancer-fighting properties

Lidocaine-;often used as numbing agent for outpatient medical procedures-;activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

22 Nov 2023

Nitrite analysis in pharmaceuticals: monitoring a precursor to nitrosamine

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From Metrohm Middle East FZC 22 Nov 2023

US military says national security depends on ‘forever chemicals’

The Department of Defense relies on hundreds, if not thousands, of weapons and products such as uniforms, batteries, and microelectronics that contain PFAS, a family of chemicals linked to serious health conditions.

20 Nov 2023

Cannabis shows promise in easing endometriosis pain, new research suggests

The Journal of Clinical Medicine review explores cannabis as a self-management strategy for endometriosis pain, revealing its potential to reduce gut inflammation and improve gut permeability, thereby alleviating bloating and suppressing pain through interactions with the endocannabinoid system and gut microbiota.

14 Nov 2023

Exploring nature's palette: The promising future of natural food colorants

A review in Foods journal discusses the potential of natural foods as alternatives to synthetic colorants in food products, focusing on their safety and potential health benefits. It highlights the need for more research to enhance the stability and availability of natural food coloring agents.

13 Nov 2023

Non-invasive device detects Alzheimer's and Parkinson's biomarkers with high accuracy

An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer's and Parkinson's Diseases.

13 Nov 2023

Study links lower testosterone levels with increased arthritis risk

The relationship between serological testosterone levels and arthritis among United States (US) adults.

9 Nov 2023

Lario Therapeutics receives “Company Making a Difference Award” from CDLK5 Forum, recognising its unique approach to precision medicine for genetic epilepsies

“CDLK5 Forum Award for Excellence - Company Making a Difference 2023 Pre-clinical” presented by the Loulou Foundation at the CDKL5 Forum, 6th-7th November in London

7 Nov 2023

Added calcium and phosphate in fluoride varnishes no silver bullet for fighting kids' tooth decay, study finds

The study explores the effectiveness of sodium fluoride varnishes with added calcium and phosphate versus conventional varnishes in reducing harmful bacteria in preschool children's mouths. Results indicate no significant difference between the two types of varnishes in controlling bacterial growth, calling for more research on effective ways to combat early childhood caries.

1 Nov 2023

Scientists discover hidden intricacies of sperm motility

Researchers at Stockholm University have unveiled the hidden intricacies of how sperm go from passive bystanders to dynamic swimmers.

25 Oct 2023

New insights into coronavirus E channel could lead to antiviral drugs

The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of Covid-19.

13 Oct 2023

Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

Researchers in neuropsychopharmacology challenge conventional wisdom about antidepressants' actions, revealing significant intracellular activity that influences their effectiveness. Utilizing advanced technologies, the study prompts a reevaluation of drug targeting and mechanisms, opening new avenues for treating depression.

12 Oct 2023