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Identification of first protein biomarkers to help patients with amyotrophic lateral sclerosis

A University of Pittsburgh pathologist has identified the first protein biomarkers able to diagnose patients with amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease) with near 100 percent accuracy. Before this finding, there were no known diagnostic biomarkers for this neurodegenerative disease.

18 Apr 2004

Bad hygiene may be good for you

A group of scientists at The Scripps Research Institute have found a connection between poor T cell survival in the body and the development of autoimmunity.

16 Apr 2004

Decongestant may increase blood pressure

A common ingredient in over-the-counter decongestants -- pseudoephedrine -- may increase blood pressure and the risk of life-threatening or disabling strokes in susceptible patients, researchers at Vanderbilt University Medical Center have reported.

15 Apr 2004

Muscle stem cells morph to resemble nerve cells

Taking a major step forward in stem cell biology, researchers at The University of Texas M. D. Anderson Cancer Center have turned muscle progenitor cells — stem cells that are “committed” to becoming muscle tissue — into cells that look and act like neurons (nerve cells).

14 Apr 2004

Natural medication shown to not always be a safe alternative to synthetic medication

The common perception that if medication is natural then it must be safe has recently come under fire from a researh by a Consumer Reports magazine. The consumer publication found a dozen herbal supplements, some banned in Asia, Europe and Canada but widely available in the United States, may cause cancer, kidney or liver damage and even death.

10 Apr 2004

Shunning shoulder pain can cause more damage in the long run

Senator John Kerry is one of the millions of Americans suffering from shoulder pain. Depending on the nature of the problem, conservative nonoperative methods of treatment are often recommended before surgery. However, in some instances such as Kerry’s, surgery is necessary in order to prevent more difficulties later. The American Academy of Orthopaedic Surgeons (AAOS) advises those suffering shoulder pain to consult their doctor instead of ignoring the pain. Early, correct diagnosis and treatment of shoulder problems can make a significant difference in the long run.

7 Apr 2004

Alcohol screening can spot addiction

Have you ever felt like you needed a drink? If an occasional cocktail changes into a need, it could mean an alcohol problem. National Alcohol Screening Day is April 8. In cities and towns throughout the United States, screening programs will be offered to help people determine whether they exhibit drinking behaviors that could be signs of alcohol addiction.

7 Apr 2004

New research findings in study of Rett Syndrome

Rudolf Jaenisch of the Whitehead Institute of Biomedical Research in Cambridge, MA reports in the April 6, 2004 online issue of the Proceedings of the National Academy of Sciences that introduction of the MeCP2 protein into post-mitotic nerve cells of MeCP2 mutant mice rescues the symptoms of Rett Syndrome. This raises the possibility that neurons are functionally normal in a newborn child and that neural dysfunction manifests itself only later due to prolonged MeCP2 deficiency. If correct, therapeutic strategies aimed at preventing the onset of Rett symptoms could be initiated at birth.

7 Apr 2004

Phase 3 study of drug teduglutide in patients with short bowel syndrome

Teduglutide is an analog of glucagon-like peptide 2 (GLP-2), a naturally occurring hormone that regulates the growth, proliferation and maintenance of cells lining the gastrointestinal tract. Teduglutide has been shown in animal studies and previous human clinical trials to increase the size and number of these cells, thereby increasing the absorptive surface area of the intestines.

6 Apr 2004

Drug, Nembutal can suppress activity in colon cancer cells

A barbiturate once commonly used to treat anxiety may play a role in controlling the spread of colon cancer, say researchers from The University of Texas M. D. Anderson Cancer Center.

30 Mar 2004

Cardiac sympathetic denervation the heart’s control from the sympathetic nervous system

Surgery to cut part of the nerves to the heart can reduce the risk of fainting or sudden death in young people with a heart rhythm disorder called long QT syndrome (LQTS), researchers reported in today’s rapid access issue of Circulation: Journal of the American Heart Association.

29 Mar 2004

Newly formed FAS Center for Systems Neuroscience

Harvard has long been recognized for its strength in neuroscience: Researchers in the Faculty of Arts and Sciences (FAS) are leaders in studies of behavior, perception, and brain development, while Harvard Medical School (HMS) was the first in the nation to establish a department of neurobiology.

29 Mar 2004

Snake venom launders out all stains

Purveyors of snake oil and its mythical powers may not have had it all wrong, if preliminary findings with the Florida cottonmouth, bloodstains and a washing machine stay on target. An enzyme extracted from the viper's venom appears to help launder out notoriously stubborn blood spots on clothing.

29 Mar 2004

BHF anti-smoking adverts hit nerve with general public

An incredible 94% of smokers surveyed said they recognised at least one element of the 'Give Up Before You Clog Up' campaign, with the 'dripping fat cigarette' TV advert sticking in the memories of 90% of those surveyed. The survey was conducted by leading research agency, Hall and Partners, who say the statistics beat any other advertising campaign they have worked on.

29 Mar 2004

Discovery of molecule that is part of the machinery that mediates the sense of hearing

A group of scientists at The Scripps Research Institute, at the University of California in San Diego, and at the Oregon Hearing Research Center and Vollum Institute at Oregon Health & Science University have discovered a key molecule that is part of the machinery that mediates the sense of hearing.

28 Mar 2004

A common antibiotic used to treat arthritis and acne shows promise for limiting the severity of spinal cord and brain injuries

When a fall, car crash, bullet, or knife crushes or cuts a spinal cord, the injury does not stop there. Rather, tissues continue to discharge toxic chemicals for hours, even days and weeks. These chemicals kill and disable nerve cells some distance away from the core injury, compounding the damage and making rehabilitation more difficult or impossible.

26 Mar 2004

Alcohol boosts the pleasurable effects of nicotine

In tests on human volunteers, Duke University Medical Center researchers have found that even small amounts of alcohol boost the pleasurable effects of nicotine, inducing people to smoke more when drinking alcoholic beverages. The findings provide a physiological explanation for the common observation that people smoke more in bars. The findings also explain statistics showing that alcoholics tend to smoke more than non-alcoholics, and that smokers are more likely to be alcoholics.

24 Mar 2004

Oregon Stem Cell Center Hunt for Human Disease Therapies

Oregon Health & Science University's fast-growing stem cell research program, which already has made significant strides in the hunt for human disease therapies, now has a place to call home.

23 Mar 2004

Risk Assessment of Diabetic Retiopathy Improved by Screening Methods

Eli Lilly and Company as part of a continued commitment to innovation in the area of diabetes, announced today the creation of a strategic relationship with EyeTel Imaging, Inc. to improve screening and detection of diabetic retinopathy, one of the potentially devastating diabetic microvascular complications. The agreement, which expands the relationship between the two companies, will provide EyeTel with on-going operational support from Lilly, allowing EyeTel to provide primary care physicians access to state-of-the-art patient risk assessment tools and education programs.

23 Mar 2004

System for guiding cell migration, adhesion has biomedical and regenerative medical applications

Scientists at the University of Toronto are taking regenerative medicine to a new dimension with a process for guiding nerve cells that could someday help reconnect severed nerve endings.

23 Mar 2004