Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Interdisciplinary project aims to decode human kinome in brain function and disease

The Chan Zuckerberg Initiative (CZI) announced four multi-year Exploratory Cell Networks grants for researchers exploring the frontiers of genomics, cell biology, and synthetic biology by developing new measurement technologies.

29 Feb 2024

Brain waves drive waste removal during sleep, study finds

There lies a paradox in sleep. Its apparent tranquility juxtaposes with the brain's bustling activity. The night is still, but the brain is far from dormant.

28 Feb 2024

Neuroscientists uncover surprising role of glia in regulating neuronal responses in the brain

Neuroscientists at Fred Hutchinson Cancer Center have found that an often-overlooked type of brain cell called glia has more of a role in brain function than previously thought.

28 Feb 2024

Abdominal fat's impact on brain health more pronounced in middle-aged men at high risk of Alzheimer's

The impact of abdominal fat on brain health and cognition is generally more pronounced in middle-aged men at high risk of Alzheimer's disease as opposed to women, according to researchers at Rutgers Health.

27 Feb 2024

Study uncovers a biological role of transmembrane protein TMEM208

A recent study conducted in the lab of Dr. Hugo J. Bellen, distinguished service professor at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, has discovered a biological role of a specific transmembrane protein called TMEM208.

23 Feb 2024

Neural cell culture model sheds light on the intricate mechanisms underlying neurodegeneration

Scientists at the University of Zurich have developed an innovative neural cell culture model, shedding light on the intricate mechanisms underlying neurodegeneration.

22 Feb 2024

Simple blood test to detect Alzheimer's disease may replace more invasive diagnostic methods

A simple blood test to diagnose Alzheimer's disease soon may replace more invasive and expensive screening methods such as spinal taps and brain scans.

22 Feb 2024

Chan Zuckerberg Initiative funds Notre Dame research on aging and neurodegeneration

The University of Notre Dame has received a Collaborative Pairs Pilot Project Award from the Chan Zuckerberg Initiative to study genes that affect neurodegenerative diseases, such as Alzheimer's disease.

21 Feb 2024

COVID-19's neurological effects linked to immune response, not direct viral attack

Study identifies neurocognitive symptoms in COVID-19 patients as a reaction to systemic infection rather than direct brain infection, highlighting changes in the brain's immune response and synaptic organization.

21 Feb 2024

Study proposes novel approach to slow neuromuscular degeneration in ALS patients

A study led by the Center for Biomaterials and Tissue Engineering of the Universitat Politècnica de València, member of Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, in collaboration with the Instituto de Investigación Sanitaria La Fe and the University of Zaragoza proposes a novel approach to slow neuromuscular degeneration in patients with Amyotrophic Lateral Sclerosis.

20 Feb 2024

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects."

15 Feb 2024

Study links Agent Orange exposure to neurodegenerative diseases

Agent Orange, an herbicide used during the Vietnam War, is a known toxin with wide-ranging health effects.

14 Feb 2024

Study uncovers more than one hundred key genes linked to DNA damage

More than one hundred key genes linked to DNA damage have been uncovered through systematic screening of nearly 1,000 genetically modified mouse lines, in a new study published today (14 February) in Nature.

14 Feb 2024

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain.

12 Feb 2024

Study reveals role of protein modification in neurodegenerative disease progression

Neurodegenerative diseases, such as Alzheimer's and Parkinson's, present a significant health challenge, affecting over 50 million people globally.

12 Feb 2024

Large Language Models promise to revolutionize neuroscience research

The past year has seen major advances in Large Language Models (LLMs) such as ChatGPT. The ability of these models to interpret and produce human text sources (and other sequence data) has implications for people in many areas of human activity.

9 Feb 2024

Gut health linked to Alzheimer's progression, study suggests diet as potential therapy

Study reviews the intricate relationship between diet, gut microbiome diversity, and Alzheimer’s disease progression, suggesting gut health could play a key role in managing the disease.

3 Feb 2024

Improving mitochondrial metabolism could be a potential therapeutic target for Alzheimer's

Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells.

30 Jan 2024

What are the capabilities of a commercially available p-tau217 immunoassay to identify Alzheimer disease pathophysiology?

Researchers determined the utility of a novel and commercially available immunoassay for plasma phosphorylated tau 217 to detect Alzheimer's Disease pathology and evaluate reference ranges for abnormal amyloid β and longitudinal change across three selected cohorts.

24 Jan 2024

SynNeurGe: A new biological classification system for Parkinson's disease research

One of the things that makes developing effective treatments for Parkinson's disease so challenging is its complexity.

23 Jan 2024