Neurodegenerative Disease News and Research

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Genes affecting worm behavior found to be relevant to neurological disease in humans

As an undergraduate student in The University of Texas at Arlington's Honors College, Hannah Selvarathinam knew she wanted to conduct research. Near the end of her first year at UTA, the Keller native reached out to the lab of biology Assistant Professor Piya Ghose.

30 Apr 2024

Do SARS-CoV-2 infections cause long-term loss of smell and taste?

The long-term smell and taste-associated outcomes of coronavirus disease 2019 (COVID-19) using validated psychophysical tests.

29 Apr 2024

New imaging technique provides a much closer look at fibril assemblies

A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies, stacks of peptides like amyloid beta, most notably associated with Alzheimer's disease.

26 Apr 2024

Genetic variants linked to Parkinson's risk from pesticide exposure

A new UCLA Health study found certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease.

25 Apr 2024

Ophthalmological method can be used to monitor neurodegeneration in Parkinson's patients

A study by the University of the Basque Country (UPV/EHU) and Biobizkaia proposes using an available, simple, non-invasive tool to monitor this neurodegeneration.

22 Apr 2024

New platform can deliver gene therapy precisely to specific areas of the brain

A novel approach to gene therapy is improving lives in ways once thought impossible. Researchers at The Ohio State University Wexner Medical Center and College of Medicine have developed a new platform to deliver the gene therapy precisely to specific areas of the brain.

18 Apr 2024

Hypertension linked to higher dementia risk in middle-aged patients

Study investigates the relationship between hypertension in middle-aged individuals and the increased risk of developing dementia, utilizing the CAIDE score for dementia risk prediction in a cohort of white Argentinian hypertensive patients.

4 Apr 2024

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in the brain.

3 Apr 2024

Fasting's potential in fighting cognitive decline needs more human trials

Despite promising animal studies on fasting and caloric restrictions for neurodegenerative diseases, human clinical trials are scarce, underscoring the need for more research to validate these interventions for cognitive decline.

2 Apr 2024

Irritable bowel syndrome not linked to higher Parkinson's risk, study finds

Research investigates the association between irritable bowel syndrome (IBS) and Parkinson's disease (PD), revealing that IBS is not linked to an increased overall risk of PD. Subgroup analyses suggest that certain IBS populations may have a lower risk of developing PD.

31 Mar 2024

Dietary vitamin A shows promise in Alzheimer's disease intervention, study finds

Study explored the impact of dietary vitamin A on gut microbiota and intestinal transcriptome, revealing its potential in Alzheimer's disease (AD) pathology and cognitive functions in mice.

28 Mar 2024

Breakthrough discovery points to potential treatment for rare neurodegenerative disease

Imagine being middle-aged and starting to feel that you are off balance a lot and that you are having a hard time coordinating your movements.

27 Mar 2024

Aging linked to length of genes, study suggests

Aging may be less about specific "aging genes" and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers in an opinion piece publishing March 21 in the journal Trends in Genetics.

22 Mar 2024

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health.

20 Mar 2024

Skin biopsy test shows promise in diagnosing Parkinson's disease and synucleinopathies

In a paper published in the Journal of the American Medical Association (JAMA), neurologists at Beth Israel Deaconess Medical Center (BIDMC) showed that a simple skin biopsy test detects an abnormal form of alpha-synuclein, the pathological hallmark of Parkinson's disease and the subgroup of neurodegenerative disorders known as synucleinopathies, at high positivity rates.

20 Mar 2024