Platelets News and Research

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Exploiting platelets for antitumor drug delivery and immune modulation of tumor microenvironment

Announcing a new publication for Acta Materia Medica journal. Platelets are blood components traditionally believed to have fundamental roles in vascular hemostasis and thrombosis.

15 May 2023

New approach addresses the challenge of directly connecting genetic variants to human traits, health

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

Vein-on-a-chip model can help understand the mechanisms of blood clot formation

Blood clot researchers could benefit from a new device that mimics a human vein, replacing the need for animals for some studies.

27 Apr 2023

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Study aimed to test the antibacterial and cytotoxic effects of bee venom-loaded chitosan nanoparticles (BV-loaded CS-NPs) against Staphylococcus aureus. The results showed that BV-loaded CS-NPs had enhanced antibacterial activity and minimal cytotoxicity, making it a promising antibiotic alternative.

24 Apr 2023

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer.

17 Apr 2023

Cornell receives $9.5 million NIH grant for chronic fatigue research

A Cornell multidisciplinary research center that studies chronic fatigue syndrome has received a five-year, $9.5 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Disease – funding that will enable experts from disparate fields to work together on the mysterious and debilitating condition.

11 Apr 2023

Study explains why leukemia survivors experience negative effects on blood formation decades later

Contrary to previous belief, stem cells, from which all new blood cells are formed, remain in bone marrow in the blood cancer type acute lymphocytic leukemia.

5 Apr 2023

Researchers discover a new switching point that regulates hemostasis and thrombosis

The glycoprotein V of the blood platelets is an important switch point for hemostasis and thrombus formation. This new finding could have great clinical potential.

24 Mar 2023

Music-listening interventions can make medications more effective

While listening to a favorite song is a known mood booster, researchers at Michigan State University have discovered that music-listening interventions also can make medicines more effective.

21 Mar 2023

COVID-19 vaccination may reduce the risk of thrombosis in hospitalized patients

A study published in the British Journal of Hematology describes that coronavirus disease 2019 (COVID-19) vaccines are effective in reducing thrombotic events and preventing disease severity in individuals with breakthrough severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

10 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Addition of sotatercept to existing therapy shows promise for the treatment of pulmonary arterial hypertension

Patients with pulmonary arterial hypertension (PAH), a severe, progressive condition that affects the heart and lungs, who were treated with the novel first-in-class medication sotatercept on top of existing therapy experienced significant improvements in walking distance via a six-minute walking test—the study's primary endpoint and a validated surrogate for functional improvement and reduced symptom burden.

6 Mar 2023

Research identifies a possible treatment strategy for rare bone marrow failure syndrome

Bone marrow is the spongy tissue inside bone responsible for making red blood cells, white blood cells and platelets. Bone marrow failure syndromes lead to an increased risk of developing dangerous infections, anemia and an increased risk of blood cancers.

2 Mar 2023

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

Researchers assessed the role of renalase as an independent predictor of COVID-19-related mortality.

2 Mar 2023

Popular artificial sweetener associated with elevated risk of heart attack and stroke, study shows

New Cleveland Clinic research showed that erythritol, a popular artificial sweetener, is associated with an increased risk of heart attack and stroke.

27 Feb 2023

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone.

23 Feb 2023

Integrated NGS system can deliver accurate, genomics-based diagnoses to accelerate treatment for myeloid neoplasms

Identifying recurrent genetic alterations in myeloid neoplasms has improved diagnosis and expanded targeted treatments available to patients. However, treatment initiation can be delayed by the variable and lengthy turnaround times involved in testing for these alterations.

7 Feb 2023

Bone marrow transplants may prevent blood vessel disease in patients with sickle cell disease

Bone marrow transplants prevented or improved blood vessel disease in the brains of adults with sickle cell disease, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Dual antiplatelet therapy for minor or a warning stroke is underused especially among women

Despite evidence that starting two blood-thinning medications shortly after a minor stroke or a warning stroke (transient ischemic attack - TIA) may prevent a second – possibly more serious – clot-caused stroke within a few months, the treatment regimen is underused especially among women, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Researchers evaluated the clinical and genetic characteristics of acute myeloid leukemia (AML) patients with a mutant Ikaros zinc finger protein 1 (IKZF1).

2 Feb 2023

Platelets News and Research

Exploiting platelets for antitumor drug delivery and immune modulation of tumor microenvironment

New approach addresses the challenge of directly connecting genetic variants to human traits, health

Vein-on-a-chip model can help understand the mechanisms of blood clot formation

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

Cornell receives $9.5 million NIH grant for chronic fatigue research

Study explains why leukemia survivors experience negative effects on blood formation decades later

Researchers discover a new switching point that regulates hemostasis and thrombosis

Music-listening interventions can make medications more effective

COVID-19 vaccination may reduce the risk of thrombosis in hospitalized patients

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Addition of sotatercept to existing therapy shows promise for the treatment of pulmonary arterial hypertension

Research identifies a possible treatment strategy for rare bone marrow failure syndrome

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

Popular artificial sweetener associated with elevated risk of heart attack and stroke, study shows

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Integrated NGS system can deliver accurate, genomics-based diagnoses to accelerate treatment for myeloid neoplasms

Bone marrow transplants may prevent blood vessel disease in patients with sickle cell disease

Dual antiplatelet therapy for minor or a warning stroke is underused especially among women

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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