Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs (genetic material that instructs the body on how to make proteins), are degraded.

1 May 2024

Unlocking the secrets of long-lived hematopoietic stem cells

Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells (HSCs) are remarkably long-lived. HSCs are blood-forming cells – they give rise to rapidly dividing progenitor cells, which in turn generate hundreds of billions of cells to fulfill the daily demand of oxygen-delivering red blood cells, disease-fighting white blood cells and clot-forming platelets.

30 Apr 2024

U of T researchers develop new approach for controlling neuron generation in Parkinson's disease

Researchers at the University of Toronto have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective treatments.

30 Apr 2024

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

30 Apr 2024

Unlocking the mechanisms of pluripotent cell's fate determination

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

29 Apr 2024

Human mini-lungs mimic animal response to nanomaterials

Human mini-lungs grown by University of Manchester scientists can mimic the response of animals when exposed to certain nanomaterials.

27 Apr 2024

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

26 Apr 2024

Study finds rise in volumes and survival after hematopoietic cell transplants among racial/ethnic minorities

The volume of hematopoietic cell transplants rose among all racial/ethnic groups, but grew faster among African Americans and Hispanics compared with Non-Hispanic white individuals, mirroring changes in population growth rates.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

Research explores how moms' obesity reprograms babies

Research increasingly suggests that when a woman with obesity becomes pregnant, a process of "fetal reprogramming" increases the risk that her baby will face problems like obesity, Type 2 diabetes and liver disease earlier in life.

23 Apr 2024

Womb pressure shapes facial features, UCL study reveals

Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study led by UCL researchers.

23 Apr 2024

Unveiling pancreatic mysteries: 3D imaging redefines islet cell distribution

Researchers at Umeå University have succeeded in imaging an entire human organ, a pancreas, in microscopic resolution.

22 Apr 2024

Machine learning reveals age-related decline in stemness across human tissues

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 7, entitled, "Evidence of a pan-tissue decline in stemness during human aging."

16 Apr 2024

Melatonin shows promise in preventing obesity, study finds

Two international studies led by the University of Granada (UGR) have confirmed that melatonin helps prevent obesity.

16 Apr 2024

First comprehensive atlas sheds new light on processes underlying age-related muscle changes

How muscle changes with aging, and tries to fight its effects, is now better understood at the cellular and molecular level with the first comprehensive atlas of aging muscles in humans.

15 Apr 2024

Research sheds light on post-sepsis immune suppression mechanism

Severe sepsis from bacterial or viral infections can be life-threatening and even people recovering from severe sepsis may experience long-lasting effects on the immune system, making them more susceptible to recurrent infections.

13 Apr 2024

Research offers insights into facial development at the cellular level

Mother Nature is an artist, but her craft of creating animal faces requires more than a paintbrush and palette. Such highly complex shapes originate from their respective transient neural crest cells.

12 Apr 2024

New technique connects lab-grown "neural organoids" to resemble brain circuits

The idea of growing a functioning human brain-like tissues in a dish has always sounded pretty far-fetched, even to researchers in the field.

10 Apr 2024

Periostin may be a novel therapeutic target for treating esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) accounts for around 90% of esophageal cancers, especially in East Asia.

9 Apr 2024

Stem Cells News and Research

Further Reading

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

Unlocking the secrets of long-lived hematopoietic stem cells

U of T researchers develop new approach for controlling neuron generation in Parkinson's disease

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Unlocking the mechanisms of pluripotent cell's fate determination

Human mini-lungs mimic animal response to nanomaterials

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Study finds rise in volumes and survival after hematopoietic cell transplants among racial/ethnic minorities

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

Research explores how moms' obesity reprograms babies

Womb pressure shapes facial features, UCL study reveals

Unveiling pancreatic mysteries: 3D imaging redefines islet cell distribution

Machine learning reveals age-related decline in stemness across human tissues

Melatonin shows promise in preventing obesity, study finds

First comprehensive atlas sheds new light on processes underlying age-related muscle changes

Research sheds light on post-sepsis immune suppression mechanism

Research offers insights into facial development at the cellular level

New technique connects lab-grown "neural organoids" to resemble brain circuits

Periostin may be a novel therapeutic target for treating esophageal squamous cell carcinoma

Stem Cells eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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