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Heightened risk of adverse neonatal outcomes from prenatal exposure to both cannabis and nicotine

A recent JAMA Network Open study found that combined prenatal use of nicotine and cannabis significantly increases risks for adverse perinatal outcomes, such as higher rates of hypertensive disease, preterm delivery, and elevated infant mortality compared to using neither or only one substance.

9 May 2024

Underdiagnosed and common: Study highlights neuropathy's hidden toll

Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a study published in the May 8, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

8 May 2024

Brain-computer interface translates ALS patient's brain activity into spoken words

Researchers successfully used a brain-computer interface to synthesize speech directly from brain activity in an ALS patient, achieving 80% word recognition accuracy by listeners, showcasing the interface's potential for aiding communication in severe speech impairments.

8 May 2024

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

A study published in Nature Medicine delineates how APOE4 homozygosity distinctly accelerates Alzheimer's disease pathology and biomarkers from the age of 55, suggesting a unique form of the disease and a potential focus for targeted therapies.

8 May 2024

New Quartet nanocage vaccine shows promise against coronavirus variants

Researchers have developed a novel vaccination approach using Quartet nanocages that display receptor-binding domains (RBDs) from different sarbecoviruses, showing enhanced immune responses and potential protection against diverse coronavirus strains including SARS-CoV-2 and its variants.

8 May 2024

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists at Rutgers University–New Brunswick have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder.

6 May 2024

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4 homozygotes- show biological characteristics of Alzheimer's pathology in the brain or biomarkers of this disease in cerebrospinal fluid and PET scans.

6 May 2024

Personalized screening approach may better predict preeclampsia in the first trimester of pregnancy

A new screening algorithm for preeclampsia combining maternal history, ultrasound data and several tests for blood markers may better predict the majority of preeclampsia cases in the first trimester of pregnancy, when it may still be preventable, according to new research published today in Hypertension, an American Heart Association journal.

6 May 2024

Complex Regional Pain Syndrome treatment shows promise for recovery

Complex Regional Pain Syndrome (CRPS) is a chronic and debilitating pain disorder, typically considered lifelong with limited treatment options. Now, groundbreaking research finds that early detection and effective treatment can lead to significant recovery within 18 months, offering hope to millions of people worldwide.

6 May 2024

New influenza vaccine strategies aim to enhance protection with T-cell responses

A recent review highlights the need for innovative influenza vaccines that combine T-cell and antibody responses to enhance protection across multiple strains and seasons.

6 May 2024

Differences in leading causes of disease burden between males and females

A recent study reveals that males bear a higher disease burden overall, while females experience a higher burden from seven specific conditions, emphasizing the need for tailored health interventions.

5 May 2024

Long-term impact of COVID-19 on body composition explored

COVID-19 may also affect body composition, even in those who did not acquire the infection.

5 May 2024

Inflammatory disease not major risk factors for severe COVID-19, focus on comorbidities urged

Severe coronavirus disease 2019 (COVID-19) outcomes in patients with immune-mediated inflammatory diseases (IMIDs).

3 May 2024

Columbia researchers uncover brain's ability to control inflammation

The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice from researchers at Columbia's Zuckerman Institute.

2 May 2024

New brain connectivity maps offer insights into human consciousness

In a paper titled, "Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness," published today in Science Translational Medicine, a group of researchers at Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, and Boston Children's Hospital, created a connectivity map of a brain network that they propose is critical to human consciousness.

2 May 2024

Syndrome News and Research

Heightened risk of adverse neonatal outcomes from prenatal exposure to both cannabis and nicotine

Underdiagnosed and common: Study highlights neuropathy's hidden toll

Brain-computer interface translates ALS patient's brain activity into spoken words

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

New Quartet nanocage vaccine shows promise against coronavirus variants

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Personalized screening approach may better predict preeclampsia in the first trimester of pregnancy

Complex Regional Pain Syndrome treatment shows promise for recovery

New influenza vaccine strategies aim to enhance protection with T-cell responses

Differences in leading causes of disease burden between males and females

Long-term impact of COVID-19 on body composition explored

Inflammatory disease not major risk factors for severe COVID-19, focus on comorbidities urged

Columbia researchers uncover brain's ability to control inflammation

New brain connectivity maps offer insights into human consciousness

New biomarkers identified for predicting psychosis risk in 22q11.2 deletion syndrome

Physical activity may reduce depression in those prone to internet overuse and emotional regulation difficulties

Research offers hope to millions of people with complex regional pain syndrome

Vaping poses unexpected risks to eye health, study finds

New approach to inhibit strep’s DNA-cleaving enzymes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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