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Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

24 Apr 2024

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

24 Apr 2024

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

A novel diagnostic model using machine learning (ML).

24 Apr 2024

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

The U.S. Food and Drug Administration (FDA) has approved the immunotherapy-boosting drug N-803, which is marketed under the brand name Anktiva, to be used in combination with the immunotherapy Bacillus Calmette-Guerin (BCG) for the treatment of patients with BCG-unresponsive non–muscle-invasive bladder cancer.

23 Apr 2024

Longitudinal multi-omics monitoring paves the way for early pancreatic cancer diagnosis

A new case report published in the peer-reviewed OMICS: A Journal of Integrative Biology describes how longitudinal multi-omics monitoring (LMOM) helped to detect a precancerous pancreatic tumor and led to a successful surgical intervention.

23 Apr 2024

Study uncovers aspirin's role in colorectal cancer development and progression

Long-term daily use of aspirin can help to prevent the development and progression of colorectal cancer, but the mechanisms involved have been unclear.

22 Apr 2024

Exploring serine and glycine metabolism in hepatocellular carcinoma

Targeted therapy and immunotherapy have emerged as treatment options for hepatocellular carcinoma (HCC) in recent years. The significance of serine and glycine metabolism in various cancers is widely acknowledged.

22 Apr 2024

Liver cells effectively serve as immune checkpoint regulating anti-cancer immunity

Liver inflammation, a common side-effect of cancers elsewhere in the body, has long been associated with worse cancer outcomes and more recently associated with poor response to immunotherapy.

22 Apr 2024

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

The role of neighborhood-level disparities in determining shorter breast cancer-specific survival.

22 Apr 2024

Engineered peptides show promise in cancer immunotherapy

In a new study published today in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cancer Center have designed a new method for developing immunotherapy drugs using engineered peptides to elicit a natural immune response inside the body.

22 Apr 2024

Cruciferous vegetables may offer new hope for inflammatory bowel disease management

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Tumor News and Research

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

New system personalizes chemotherapy doses for cancer patients

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

Longitudinal multi-omics monitoring paves the way for early pancreatic cancer diagnosis

Study uncovers aspirin's role in colorectal cancer development and progression

Exploring serine and glycine metabolism in hepatocellular carcinoma

Liver cells effectively serve as immune checkpoint regulating anti-cancer immunity

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

Engineered peptides show promise in cancer immunotherapy

Cruciferous vegetables may offer new hope for inflammatory bowel disease management

New AI tool 'TORCH' successfully identifies cancer origins in unknown primary cases

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

New trials show promise for immune checkpoint blockers in early-stage lung cancer

Breakthrough imaging method enhances precision in prostate cancer treatment

New research pinpoints key pathways in prostate cancer's vulnerability to ferroptosis

Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients

Study findings better define the genetic landscape of neuroendocrine tumors of the cervix

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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