Cell Biology

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Counteracting premature aging

Aging is the continuing process of such stress exposures, and with advancing age (normal aging), we must carry lots of senescent cells within our bodies. Senescent cells also often provide some ‘bad influences’ to surrounding healthy cells; such as chronic inflammation and tumorigenesis

14 Aug 2017

Salivary peptide promotes wound healing, research reveals

A study published online in The FASEB Journal delves into the mystifying fact that wounds in your mouth heal faster and more efficiently than wounds elsewhere.

7 Aug 2017

Pitt researcher aims to develop 'smart biomaterials' for reprogramming mammalian cell signaling

Through a process called cell signaling, cells collaborate on necessary functions such as responding to changes in the environment, fighting off threats to the body, or regulating the basic processes that keep the body alive.

4 Aug 2017

MIT engineers devise noninvasive way to assess cell's mechanical properties

The stiffness or elasticity of a cell can reveal much about whether the cell is healthy or diseased. Cancer cells, for instance, are known to be softer than normal, while asthma-affected cells can be rather stiff.

3 Aug 2017

TUM scientists provide new insights into development of T cells

When T cells encounter an antigen, they proliferate and produce various types of daughter cells. A team at the Technical University of Munich has now refuted the prevailing hypothesis that this immune response is largely predetermined by the individual structure of the T cell receptor.

2 Aug 2017

WPI researchers receive NIH grant to develop heart muscle patch using biopolymer microthreads

A research team at Worcester Polytechnic Institute has been awarded a $452,000 National Institutes of Health grant to bioengineer a patch to help cardiac muscle beat more strongly and efficiently after a heart attack.

31 Jul 2017

Penn researchers discover how DNA damage turns immune cells against cancer

Cancer is essentially a disease of the cell replication cycle. The goal of treating the disease is to permanently kill off the cells that replicate with abandon without any molecular brakes.

31 Jul 2017

Bringing highly potent cell therapy products to market

There are two main challenges and both relate to manufacturing. The first one is to make sure you can manufacture therapies with reasonable costs and the second one is to make sure that you can balance the capacity you need with the demands.

31 Jul 2017

Researchers compare bone-healing effects of three low-dose growth factors

Researchers compared the effects of three bone growth factors to bone morphogenetic protein 2 (BMP2) -- the most commonly used agent for repair of large bone defects, which is not without risks at the doses required--and showed significant bone-healing effects including the formation of new blood vessels at low doses relative to BMP2.

28 Jul 2017

Estrogen uses certain cell type as 'mediator' for beneficial effects on the bone, research shows

The female sex hormone estrogen plays an important role in the structural stability of bones. To date, however, it had been unclear exactly which cells were involved in the hormone's protective function in preventing changes in bone density.

28 Jul 2017

Scientists uncover link between backup pathogen-fighting system and mutations in Crohn's patients

Genes that regulate a cellular recycling system called autophagy are commonly mutated in Crohn's disease patients, though the link between biological housekeeping and inflammatory bowel disease remained a mystery. Now, researchers at UT Southwestern Medical Center have uncovered an intriguing clue.

28 Jul 2017

New approach may improve translation of immunological research findings

Mouse models have advanced our understanding of immune function and disease in many ways but they have failed to account for the natural diversity in human immune responses.

27 Jul 2017

Research shows key role of diffusion dynamics in stem cell differentiation and tissue development

Gradients of molecular signaling factors play an essential role in numerous events in embryonic development, from patterning limb and organ formation to the intricate shaping of the brain and neuroanatomical architecture.

27 Jul 2017

US scientists make advances in modifying human embryos

American Scientists have managed to edit and improve the DNA of human embryos in an effort to correct the gene defects that cause inherited diseases.

27 Jul 2017

Scientists uncover mechanism that keeps cells in the right places

Scientists have uncovered how cells are kept in the right place as the body develops, which may shed light on what causes invasive cancer cells to migrate.

26 Jul 2017

Stem cells in the brain found to regulate aging

Scientists at Albert Einstein College of Medicine have found that stem cells in the brain's hypothalamus govern how fast aging occurs in the body.

26 Jul 2017

Scientists reveal communication system between knee joint and developing bones in mice

Scientists from the Memorial Sloan Kettering Cancer Center, US, have revealed a communication system between the knee joint and developing bones in mice, which controls bone growth during early development and after injury.

25 Jul 2017

Princeton scientists test cell-culture system to aid study of HBV infections

Scientists from Princeton University's Department of Molecular Biology have successfully tested a cell-culture system that will allow researchers to perform laboratory-based studies of long-term hepatitis B virus (HBV) infections

25 Jul 2017

Low vitamin D may affect recovery of injured corneas

Injury or disease in combination with too little vitamin D can be bad for the window to your eyes. The three-layer, transparent cornea at the front of the eyes focuses the light coming in. But its prominent position also puts it at risk for injury from an errant mascara wand or over-prodding finger or a car accident.

24 Jul 2017

LMU neurobiologists present new theory for origin of grid cells

Ludwig-Maximilians-Universitaet in Munich neurobiologists present a new theory for the origin of the grid cells required for spatial orientation in the mammalian brain, which assigns a vital role to the timing of trains of signals they receive from neurons called place cells.

21 Jul 2017