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New way of looking at MicroRNA and how it controls gene expression

A group of scientists at The Scripps Research Institute is reporting a discovery that sheds light on an area of research fundamental to everything from the normal processes that govern the everyday life of human cells to the aberrant mechanisms that underlie many diseases, including cancer and septic shock.

13 Mar 2005

RNA interference as promising therapy for ALS

Scientists at the Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland have used RNA interference in transgenic mice to silence a mutated gene that causes inherited cases of amytrophic lateral sclerosis (ALS), substantially delaying both the onset and the progression rate of the fatal motor neuron disease.

13 Mar 2005

Protein sequenced from 75,000 year old Iraqi

An international team led by researchers at the Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology in Liepzig, Germany and Washington University in St. Louis, has extracted and sequenced protein from a Neanderthal from Shanidar Cave, Iraq dating to approximately 75,000 years old.

9 Mar 2005

World's first complete articulated Neanderthal skeleton

Anthropologists have constructed the world's first complete articulated Neanderthal skeleton to expand public and scientific understanding of the group, as well as of the differences between Neanderthals and modern humans.

9 Mar 2005

Infertility - discovery could mean new treatment

A team of Japanese scientists at Osaka University led by Dr Masaru Okabe have discovered a protein essential for human sperm to fuse to an egg. The findings could well lead to new methods of treating infertility and the development of new contraceptive strategies.

9 Mar 2005

UK will vote against the declaration on human cloning

The UN declaration is non-binding and has no legal status, but it calls on countries to prohibit all forms of human cloning. This is totally unacceptable to the UK government which strongly supports stem cell research, including embryonic stem cell research which involves the use of cloning technology.

8 Mar 2005

New evidence for an African origin of modern humans

By analyzing the relationship between the geographic location of current human populations in relation to East Africa and the genetic variability within these populations, researchers have found new evidence for an African origin of modern humans.

7 Mar 2005

Vasoactive intestinal polypeptide needed by the brain's biological clock to coordinate daily rhythms

A biologist at Washington University in St. Louis is giving the VIP treatment to laboratory mice in hopes of unraveling more clues about our biological clock.

7 Mar 2005

Scientists have identified a key network that prevents damage by oxygen radicals

Reactive oxygen species (ROS), or 'oxygen radicals', have been identified as major contributors to signs of premature aging, increased cancer prevalence linked to inflammation-associated syndromes and a variety of human diseases.

6 Mar 2005

Scientists discover how substitutions are made for injured genes

If there were no bench for second-string players on a football team, who would substitute for tired or injured team members? A team of Weizmann Institute scientists has found that, if the team were made up of genes, they might pull athletes who can play a little football in a pinch from nearby basketball or rugby teams.

6 Mar 2005

Mutations in newly discovered gene, NPHP5 cause Senior-Loken syndrome

Scientists at the University of Michigan Medical School have discovered a gene called NPHP5 and found mutations in this gene that cause a rare genetic disease called Senior-Loken syndrome. Children with this syndrome develop a type of cystic kidney disease called nephronophthisis, as well as a form of blindness called retinitis pigmentosa.

3 Mar 2005

Molecule from South American tree Quillaja, helps battle disease

The first synthesis of QS-21A, a medicinally important molecule that helps the body battle disease, has been achieved by chemists at the University of Illinois at Urbana-Champaign.

1 Mar 2005

Nature’s most sophisticated biological weapon

Nature’s most sophisticated biological weapon, snake venom, largely evolved from bits of body parts a Melbourne researcher has found.

1 Mar 2005

Scientists re-produce the human body's own cancer-killing cells through gene therapy

New hope to cancer sufferers comes from research by South Korean scientists who have found a way to re- produce the human body's own cancer-killing cells through gene therapy.

1 Mar 2005

Scientists gain new insight into DiGeorge syndrome

A collaboration of European scientists has uncovered new insight into the most common chromosomal microdeletion syndrome in humans.

28 Feb 2005

Scientists discover the origin of hydration force

Scientists at the Universitat Autònoma de Barcelona and Imperial College London have discovered the origin of hydration force, a phenomenon that causes some complex chemical and biochemical species (including DNA and other electrostatically charged molecules) to repel at short distances when surrounded by water.

28 Feb 2005

Scientists find protein that could unlock the secret to more effective treatment of TB

In a study published on 1st March 2005 in Nature Structural & Molecular Biology, a combined team discovered the structure of a protein known as resuscitation promoting factor (Rpf). Five versions of the Rpf protein exist in TB bacteria. The paper’s unveiling of the molecular structure of Rpf could be crucial to the treatment of TB in the future.

28 Feb 2005

Protein to protein interaction map for a better insight in cancer development

With the completion of the genome sequence of a number of organisms, analysis of the gene products, the proteins, is the on-going challenge.

28 Feb 2005

Scientists identify immune-system mutation

A team of Fox Chase Cancer Center scientists led by immunologist Dietmar J. Kappes, Ph.D., has identified the genetic mutation that keeps a mouse strain from developing white blood cells, or lymphocytes, called helper T cells. The report by Kappes and his colleagues appears in the Feb. 24 issue of Nature.

27 Feb 2005

Scientists have regenerated a damaged optic nerve

This achievement, which occurred in laboratory mice and is described in the March 1, 2005 issue of the Journal of Cell Science, holds great promise for victims of diseases that destroy the optic nerve, and for sufferers of central nervous system injuries.

24 Feb 2005