Molecular & Structural Biology

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Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Alcohol exposure leads to accumulation of oxidatively damaged proteins in neuronal cells. Differentiated cells are more susceptible to alcohol-induced oxidative protein damage despite higher resistance to cytotoxicity.

9 May 2024

Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

Mutations in the MAGEL2 gene, which cause Schaaf-Yan syndrome (SYS) —an ultra-rare disease that affects neuronal and cognitive development— generate truncated, non-functional proteins that tend to accumulate in the cell nucleus.

8 May 2024

Bacterial fatty acid metabolite identified as key player in immune regulation

Gut microbiota or the population of microbial inhabitants in the intestine, plays a key role in digestion and maintenance of overall health.-

7 May 2024

Enzyme implicated in telomere repair offers new avenues for cancer therapy

A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can lead to telomere shortening and genomic instability that can cause cancer.

7 May 2024

Protein profiling reveals impact of aging and resistance training on skeletal muscle proteome

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training."

2 May 2024

Bio-Rad launches three StarBright Red Dyes and expands range of antibody markers conjugated to StarBright Violet Dyes to enhance immunology research

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From Bio-Rad Laboratories 1 May 2024

Newly developed organoid model can be used to study thymus function

Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus.

29 Apr 2024

Study reveals brown fat's built-in mechanism and potential obesity treatment

Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that's different from the white fat around our belly and thighs that we are more familiar with.

29 Apr 2024

Research uncovers Blautia bacteria's crucial role in gut health and disease protection

A low-fiber “Western diet” causes damage to the protective mucus barrier in the gut, and such damage can increase the risk of inflammation and infection.

29 Apr 2024

New imaging technique provides a much closer look at fibril assemblies

A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies, stacks of peptides like amyloid beta, most notably associated with Alzheimer's disease.

26 Apr 2024

Ohio State study reveals bacterial defense mechanism against phages

One of the many secrets to bacteria's success is their ability to defend themselves from viruses, called phages, that infect bacteria and use their cellular machinery to make copies of themselves.

26 Apr 2024

Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.

25 Apr 2024

Yeast study reveals evolutionary history of iron uptake mechanisms

Competition and cooperation are fundamental forces that govern the evolutionary and ecological dynamics among species.

25 Apr 2024

U-M scientists develop new tool to better understand neuronal signaling

University of Michigan researchers have developed a new tool to better understand how chemicals like dopamine and epinephrine interact with neurons.

23 Apr 2024

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres.

22 Apr 2024

B Medical Systems’ Solar Direct Vaccine Refrigerator and Ice-Pack Freezer, the TCW40SDD, Receives the ACT Label

B Medical Systems, a leading player in the medical cold chain industry, is proud to announce that its Solar Direct Drive Vaccine Refrigerator and Ice-Pack Freezer, TCW40SDD, has received the prestigious ACT label from My Green Lab.

From B Medical Systems S.à r.l 18 Apr 2024

Study reveals structural dynamics of key hearing receptor

Professor Yunje Cho's research team from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH, Republic of Korea) has collaborated with Professor Kwang Pyo Kim's group from the Department of Applied Chemistry at Kyung Hee University (KHU, ROK), Professor Vsevolod Katritch's team from the University of Southern California (USC, USA), and Professor Carol V. Robinson from the University of Oxford (UK) to uncover the mysteries surrounding a specific receptor protein associated with hearing.

15 Apr 2024

Molecular & Structural Biology

Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

Bacterial fatty acid metabolite identified as key player in immune regulation

Enzyme implicated in telomere repair offers new avenues for cancer therapy

Protein profiling reveals impact of aging and resistance training on skeletal muscle proteome

Bio-Rad launches three StarBright Red Dyes and expands range of antibody markers conjugated to StarBright Violet Dyes to enhance immunology research

Newly developed organoid model can be used to study thymus function

Study reveals brown fat's built-in mechanism and potential obesity treatment

Research uncovers Blautia bacteria's crucial role in gut health and disease protection

New imaging technique provides a much closer look at fibril assemblies

Ohio State study reveals bacterial defense mechanism against phages

Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

Yeast study reveals evolutionary history of iron uptake mechanisms

U-M scientists develop new tool to better understand neuronal signaling

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

B Medical Systems’ Solar Direct Vaccine Refrigerator and Ice-Pack Freezer, the TCW40SDD, Receives the ACT Label

Study reveals structural dynamics of key hearing receptor

Ketamine's rapid impact on depression linked to immune system pathways

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Visualizing centriole genesis with microscopy and kinematic reconstruction techniques

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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