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Rapamycin shows promise in slowing Alzheimer's disease progression linked to seizures

Protein imbalances that increase brain cell excitability may explain why individuals with Alzheimer's disease (AD) who also experience seizures demonstrate more rapid cognitive decline than those who do not experience seizures.

2 May 2024

Nuclera eProtein Discovery system installed at leading academic institutes

Novel platform automates and accelerates protein production, enabling scale-up to mg amount in less than 48 hours.

From Nuclera 2 May 2024

ELRIG UK announces Profs Ijeoma Uchegbu and Marcus Schindler as keynote speakers at Drug Discovery 2024

Drug Discovery 2024: Connecting Minds, Transforming Science, Empowering Community will take place at ExCeL London from 2–3 October.

From ELRIG (UK) Ltd. 2 May 2024

Psilocybin found to be more effective than controls for treating depression symptoms

Psilocybin - the active ingredient in "magic" mushrooms - is a more effective treatment for symptoms of depression than controls, providing further support for its potential as an antidepressant, suggests a study published by The BMJ today.

1 May 2024

Disruption of smoking cessation medicine linked to avoidable deaths

The disruption to the supply of a prescription medicine that helps people stop smoking may have led to thousands fewer people quitting each year in England, which will lead to avoidable deaths in future, suggests a new study led by UCL (University College London) researchers.

30 Apr 2024

UNIGE's synthetic anticoagulant provides reliable alternative to heparin

Anticoagulant treatments are crucial for managing many conditions, such as heart disease, stroke and venous thrombosis.

30 Apr 2024

Psychedelic compound shows promise in stress relief for socially aggressive mice

A study in Neuropharmacology reveals that a single dose of the psychedelic compound (R)-DOI significantly improves stress-coping behaviors and reduces inflammatory markers in mice subjected to social aggression.

30 Apr 2024

Georgetown study raises concerns over aspirin's role in breast cancer treatment

A new study examining the role of aspirin in breast cancer treatment reveals critical issues related to health equity and aging that have broad implications for cancer and other disease intervention trials, say researchers from Georgetown University's Lombardi Comprehensive Cancer Center.

29 Apr 2024

Targeting skin microbiome rivals: Unveiling epilancin A37's antimicrobial mechanism

Many bacteria produce substances to gain an advantage over competitors in their highly competitive natural environment.

29 Apr 2024

Study rethinks immune system strategies to boost vaccine effectiveness

A recent Cell journal review explores key immunological assumptions to enhance our understanding of vaccine design, autoimmune responses, and immune system pathology, aiming to refine intervention strategies and theoretical frameworks in immunology.

28 Apr 2024

Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Parkinson’s UK is investing £2.1million to support Neumora Therapeutics to carry out preclinical testing of NMRA-NLRP3, a NLRP3 inhibitor with the potential to reduce inflammation and protect brain cells in Parkinson’s. NLRP3 is a protein that plays a role in regulating a number of inflammatory processes that are believed to contribute to the damage to brain cells that underlies Parkinson’s.

27 Apr 2024

Study shows surge in buprenorphine prescriptions at community health clinics

The number of health care professionals able to write a prescription for a key medication to treat addiction quadrupled at community health clinics from 2016 to 2021, according to a new study by researchers at Oregon Health & Science University.

26 Apr 2024

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

The real-world safety and efficacy of sacituzumab govitecan (SG) against metastatic triple-negative breast cancer.

26 Apr 2024

Study: Antibiotic use in moderate COVID-19 linked to clinical deterioration

Antibiotic treatment of adults hospitalized with moderate COVID-19 is associated with clinical deterioration, despite the drugs being given to over 40% of patients, according to new research being presented at this year's ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April)

25 Apr 2024

Medicare warning letters effectively cut antipsychotic prescribing for dementia patients

Warning letters from Medicare can safely cut prescribing of a powerful but risky antipsychotic, according to a new study at Columbia University Mailman School of Public Health.

25 Apr 2024

MIT study reveals circadian impact on drug metabolism in engineered livers

Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

Study links acid-reducing drugs to increased risk of migraine

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology Clinical Practice, an official journal of the American Academy of Neurology.

24 Apr 2024

Anesthetic midazolam boosts survival after cardiac arrest

If a patient is successfully resuscitated after a cardiac arrest and circulation resumes, they are not out of the woods yet.

24 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

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Pharmaceutical News

Rapamycin shows promise in slowing Alzheimer's disease progression linked to seizures

Nuclera eProtein Discovery system installed at leading academic institutes

ELRIG UK announces Profs Ijeoma Uchegbu and Marcus Schindler as keynote speakers at Drug Discovery 2024

Psilocybin found to be more effective than controls for treating depression symptoms

Disruption of smoking cessation medicine linked to avoidable deaths

UNIGE's synthetic anticoagulant provides reliable alternative to heparin

Psychedelic compound shows promise in stress relief for socially aggressive mice

Georgetown study raises concerns over aspirin's role in breast cancer treatment

Targeting skin microbiome rivals: Unveiling epilancin A37's antimicrobial mechanism

Study rethinks immune system strategies to boost vaccine effectiveness

Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Study shows surge in buprenorphine prescriptions at community health clinics

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

Study: Antibiotic use in moderate COVID-19 linked to clinical deterioration

Medicare warning letters effectively cut antipsychotic prescribing for dementia patients

MIT study reveals circadian impact on drug metabolism in engineered livers

New system personalizes chemotherapy doses for cancer patients

Study links acid-reducing drugs to increased risk of migraine

Anesthetic midazolam boosts survival after cardiac arrest

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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