Gene News and Research

Latest Gene News and Research

Mutation of a gene involved in non-small cell lung cancer linked to drug effectiveness

Mutation of a gene involved in non-small cell lung cancer (NSCLC) increases the likelihood that the drug gefitinib (Iressa™) will show a beneficial response, researchers at the Dana-Farber Cancer Institute, the National Cancer Institute (NCI) - part of the National Institutes of Health - and two other institutions announced today in the online version of Science.

29 Apr 2004

Lou Gehrig’s disease gene discovered

A gene for a rare juvenile-onset form of amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) has been isolated in families in the United States, Belgium and Austria, the Muscular Dystrophy Association (MDA) announced today.

29 Apr 2004

Results look promising in Alzheimer’s gene therapy trial

Surgical placement of genetically modified tissue directly into the brains of patients with Alzheimer’s disease, an experimental approach to delaying brain cell loss associated with the disease, leads to increased metabolic activity in the brain, with cells apparently responding to the insertion of growth factor-producing grafts

28 Apr 2004

Scientists identify six genes associated with the most common form of non-Hodgkin's lymphoma

In a paper that will be published on Thursday, April 29, 2004 in the New England Journal of Medicine, a team of scientists from Stanford University and Applied Biosystems, an Applera Corporation business, describe the identification of six genes associated with survival in diffuse large B cell lymphoma (DLBCL), the most common form of non-Hodgkin's lymphoma.

28 Apr 2004

Researchers have discovered the cause of one form of retinitis pigmentosa, a type of genetically inherited blindness

Saint Louis University researchers have discovered the cause of one form of retinitis pigmentosa, a type of genetically inherited blindness.

28 Apr 2004

Apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease

One variant of the apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease, according to an analysis of research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

$11 million for lung injury research

Northwestern University has received an $11 million Program Project Grant (PPG) from the National Institutes of Health to define the mechanisms that cause changes in the alveolar epithelium during lung injury.

27 Apr 2004

FDA mandates approval for all pancreatic enzyme replacements

The Cystic Fibrosis Foundation has announced its support of the Food and Drug Administration's (FDA) requirement that manufacturers of pancreatic enzyme replacements obtain FDA approval for their products within the next four years.

27 Apr 2004

Experimental smallpox DNA vaccine

In the first successful study of its kind, scientists have shown that a DNA-based vaccine for smallpox can protect nonhuman primates from monkeypox, a disease that resembles smallpox in humans.

27 Apr 2004

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States and may have led to a doubling of its occurrence during the past 200 years, according to a study by hereditary deafness experts at Virginia Commonwealth University.

27 Apr 2004

UK scientists have discovered cancer cells life and death scenario following anti-cancer treatment

CANCER Research UK scientists have discovered how some cancer cells choose to live and others die following anti-cancer treatment, unveiling their findings in the prestigious journal PNAS today.

26 Apr 2004

Clinical trial of enzyme replacement therapy for the treatment of Gaucher disease

Transkaryotic Therapies, Inc. today announced that it has initiated a clinical trial to evaluate the safety and clinical activity of GA-GCB, its enzyme replacement therapy for the treatment of Gaucher disease.

26 Apr 2004

New analytical approach that combines genetic and clinical data to give individualized prognosis of cancer recurrence

Researchers at Duke University have developed a new analytical approach that combines genetic and clinical data to give cancer patients an individualized prognosis of their cancer recurrence. The information could prove critical in deciding how aggressively to treat the disease following surgery.

26 Apr 2004

New cancer drug Tarceva - a breakthrough with significant survival benefit in patients with advanced lung cancer

OSI Pharmaceuticals, Inc., Genentech, Inc., and Roche today announced that a Phase III study of Tarceva™ (erlotinib HCl), an investigational HER1/EGFR-inhibitor agent in previously treated patients with non-small cell lung cancer (NSCLC), met its primary endpoint of improving overall survival, with patients receiving Tarceva™ living longer than those in the placebo arm of the study.

26 Apr 2004

Discovery shows how single genetic mutation can cause complex disorders

Bardet-Biedl syndrome (BBS), characterized by obesity, learning disabilities and eye and kidney problems, is caused by genetic mutations in the BBS family of genes. Now, researchers who've long studied the condition have discovered that genetic mutations in one of those genes, called BBS4, lead to cell death by disrupting the cells' internal "highway" system.

25 Apr 2004

Protein may help prevent autoimmune conditions like diabetes, lupus, arthritis and multiple sclerosis

A possibly important ally of the immune system that can help with the tricky task of separating friend from foe has been identified by scientists at Washington University School of Medicine in St. Louis.

23 Apr 2004

Certain cells from a mother can cause immunity illness in children

Certain cells from a mother persist in their children’s bodies and can provoke an immune response in which the child’s body attacks itself, according to Mayo Clinic research published in the current issue of the Journal of Immunology (http://www.jimmunol.org).

23 Apr 2004

Gene News and Research

Latest Gene News and Research

Mutation of a gene involved in non-small cell lung cancer linked to drug effectiveness

Lou Gehrig’s disease gene discovered

Results look promising in Alzheimer’s gene therapy trial

Scientists identify six genes associated with the most common form of non-Hodgkin's lymphoma

Researchers have discovered the cause of one form of retinitis pigmentosa, a type of genetically inherited blindness

Apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease

$11 million for lung injury research

FDA mandates approval for all pancreatic enzyme replacements

Experimental smallpox DNA vaccine

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States

UK scientists have discovered cancer cells life and death scenario following anti-cancer treatment

Clinical trial of enzyme replacement therapy for the treatment of Gaucher disease

New analytical approach that combines genetic and clinical data to give individualized prognosis of cancer recurrence

New cancer drug Tarceva - a breakthrough with significant survival benefit in patients with advanced lung cancer

Discovery shows how single genetic mutation can cause complex disorders

Protein may help prevent autoimmune conditions like diabetes, lupus, arthritis and multiple sclerosis

Certain cells from a mother can cause immunity illness in children

Japanese scientists have created a viable mouse derived from two genetic mothers with no contribution by a male animal

Clemson launches DNA learning center

New techniques to search the yeast genome for genes that help keep copied chromosomes together

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer