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Researchers uncover two classes of genetic causes for pediatric chordoma

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.

30 May 2024

Light therapy may affect healing in the brains of people who suffered traumatic brain injury

Low-level light therapy appears to affect healing in the brains of people who suffered significant brain injuries, according to a study published today in Radiology, a journal of the Radiological Society of North America.

28 May 2024

Targeting metabolic pathways to combat Epstein-Barr virus infections

The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers.

24 May 2024

Study reveals endurance exercise's impact on the biological molecules of animals and humans

As part of an ongoing national research effort to better understand how physical activity improves health and prevents disease, seven University of Colorado Department of Medicine faculty members contributed to an article recently published in Nature, an international journal of science.

22 May 2024

Inherited iron defects uncovered in endemic Indian population

Although iron deficiency anemia is the most prevalent form of anemia globally, it may be underdiagnosed due to lack of awareness or methodical screening.

20 May 2024

Breakthrough ATP sensor sheds light on cellular energy dynamics

A molecule called adenosine triphosphate (ATP) is the basic unit of biochemical energy that fuels the activities of all cells.

17 May 2024

Boosting mitochondrial health can reverse protein clumping in aging and Alzheimer's

It has long been known that a hallmark of Alzheimer's disease, and most other neurodegenerative diseases, is the clumping together of insoluble protein aggregates in the brain.

16 May 2024

Unraveling the mystery of Alzheimer's resilience at molecular level

Everyone experiences aging in their own way, and factors such as genetics, lifestyle and environment play a role in this process.

16 May 2024

Lactate is essential to buffering the effects of a carbohydrate meal, study shows

As a student competing in track and field at his Parlier high school, Robert Leija was obsessed with how to improve his performance and, in particular, prevent the buildup of lactic acid in his muscles during training.

15 May 2024

Metabolomics study finds biomarkers predicting autism in newborns

A study in Communications Biology utilized metabolomics in newborns to identify markers that might predict autism spectrum disorder (ASD), finding distinct metabolic profiles in children with ASD compared to typically developing children.

14 May 2024

Study sheds light on the crucial role of glutamate tRNA fragments in brain aging and Alzheimer's disease

A significant research paper published in the journal Cell Metabolism by the team of Prof. LIU Qiang at the University of Science and Technology of China reveals the critical role of glutamate tRNA fragments in brain aging and Alzheimer's disease.

14 May 2024

Protein mechanics key to cell nucleus entry, study finds

Researchers at the Francis Crick Institute and King's College London have discovered that how soft or rigid proteins are in certain regions can dictate how fast or slow they enter the nucleus.

13 May 2024

Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Alcohol exposure leads to accumulation of oxidatively damaged proteins in neuronal cells. Differentiated cells are more susceptible to alcohol-induced oxidative protein damage despite higher resistance to cytotoxicity.

9 May 2024

Novel head-mounted device shows promise in alleviating depression symptoms

A head-mounted device that generates an ultra-low frequency ultralow magnetic field has been found to improve the symptoms of four male patients diagnosed with major depressive disorder.

8 May 2024

Herpesvirus infection alters structure and function of mitochondria in the host cell

Researchers at the University of Jyväskylä have found that herpesvirus infection modifies the structure and normal function of the mitochondria in the host cell.

7 May 2024

Innovative nanoparticle breaks blood-brain barrier to target breast cancer and brain metastases

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a nanoparticle that can penetrate the blood-brain barrier.

6 May 2024

Study reveals crucial insights into how the Warburg effect causes dedifferentiation of cancer cells

Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming.

3 May 2024

Research highlights the link between mitochondrial calcium transport and autophagy

An article published in The Faseb Journal describes a Brazilian study analyzing the correlation between two key energy metabolism regulation processes: the absorption and release of calcium ions by mitochondria, the organelles that generate energy for cells; and autophagy induced by calorie restriction. Autophagy occurs when cells break down and reuse their own cytoplasm.

2 May 2024

Study reveals molecular changes in 19 organs due to exercise

The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought.