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Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast cancer, an aggressive form of breast cancer.

27 Mar 2024

Researchers identify new potential target for the treatment of Alzheimer's disease

Researchers at the University of Leeds and Lancaster University in the UK have identified a new potential target for the treatment of Alzheimer's disease – PDE4B.

26 Mar 2024

Nuclera joins Tech Nation’s Future Fifty program

Nuclera recognized as one of UK’s most exciting growth stage companies.

From Nuclera 20 Mar 2024

New insights into upper tract urothelial carcinoma evolution and treatment

Researchers at Weill Cornell Medicine have performed the most comprehensive analysis to date of cancer of the ureters or the urine-collection cavities in the kidney, known as upper tract urothelial carcinoma (UTUC).

18 Mar 2024

Nuclera appoints Joseph Bertelsen as Chief Commercial Officer

Key appointment to lead global commercial launch of eProtein Discovery platform

From Nuclera 14 Mar 2024

Growing mini-organs from amniotic fluid to treat conditions before birth

A pioneering approach, developed by researchers at UCL and Great Ormond Street Hospital (GOSH), means human development can be observed in late pregnancy for the first time, raising the possibility of monitoring and treating congenital conditions before birth.

5 Mar 2024

Unlocking the secrets of T follicular helper cells for better treatment strategies

T follicular helper cells (Tfh) are essential for strong antibody-mediated reactions of our immune system during infections and vaccinations. However, if they get out of control, this can cause diseases such as autoimmunity, allergies or cancer.

1 Mar 2024

Mapping the brain: How cell types and location influence Parkinson’s disease

A single-cell spatial transcriptome analysis on murine brain expression in age and disease using a Parkinson's disease.

27 Feb 2024

Physical inactivity and inflammation drive age-related gene changes in skeletal muscles

New research indicates that some age-related changes in gene and protein expression in the skeletal muscles of older individuals may be affected more by physical inactivity and chronic inflammation than primary aging, or intrinsic maturational processes.

21 Feb 2024

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

20 Feb 2024

Research demonstrates a bat species' resistance to cancer, pinpoints key genes

A study reveals Myotis pilosus bats exhibit exceptional cancer resistance through gene downregulation, offering insights into natural anticancer mechanisms.

18 Feb 2024

Glial fibrillary acidic protein levels pinpoint future dementia risk a decade in advance

Researchers identify GFAP as a potent biomarker for predicting dementia risk over a decade before clinical diagnosis, underscoring its potential for early screening and intervention in asymptomatic individuals.

13 Feb 2024

Immune protein Ku70 key in fighting bowel cancer

Study establishes Ku70's role in tumor suppression, showing that reduced expression or mutations in this DNA repair protein significantly increase intestinal cancer risk.

30 Jan 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

Researchers use a mathematical model to assess the efficacy of a new combinational therapy of AZD9496 and palbociclib for breast cancer treatment.

18 Jan 2024

Decoding blood cancer secrets to optimize CAR T therapy

Chimeric antigen receptor T-cell therapy, or CAR T, has dramatically improved the treatment of certain blood cancers. Initially approved for patients who had failed multiple lines of therapy, clinical trials have shown CAR T can be used as an earlier treatment option.

17 Jan 2024

Study reveals mangos attenuates potential against colon cancer

The chemo-preventive potential of Mangiferin (MF) (mango).

10 Jan 2024

New developments at Evosep to make clinical proteomics 100x more robust and 10x faster

J.P. Morgan Healthcare Conference – (January 8th, 2024) Evosep, a leading provider of sample preparation solutions for mass spectrometry-based proteomics, today announced a co-marketing agreement with Thermo Fisher Scientific, a world leader in serving science.

From Thermo Fisher Scientific Inc. 10 Jan 2024

Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment

Researchers developed an advanced prime editor-engineered virus-like particle (PE-eVLP) system, significantly enhancing gene editing efficiency in human cells and showing potential for treating genetic diseases.

9 Jan 2024

Itchy skin? Possible atopic dermatitis? Lavender essential oil might be just what you're looking for

Researchers demonstrate that lavender essential oils, particularly linalyl acetate, effectively suppress atopic dermatitis without skin sensitization, offering a natural, accessible treatment option.

8 Jan 2024