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Two diabetes medications more beneficial in preventing major cardiovascular events

GLP-1 receptor agonists (GLP-1s) and SGLT-2 inhibitors lower the risk of major cardiovascular events like heart attacks and severe liver complications compared to other diabetes treatments, according to data being presented Sunday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Childhood inactivity linked to increased risk of liver disease by young adulthood

Children who are sedentary for more than six waking hours a day have a significantly increased risk of severe fatty liver disease and liver cirrhosis by young adulthood, a new study finds.

3 Jun 2024

DefiniGEN and Atelerix collaborate to ship in vitro cell models internationally without the need for freezing or cryopreservation

DefiniGEN Ltd., and Atelerix Ltd., today announced they have successfully shipped in vitro liver models from the UK to a top tier pharma customer in the US. The agreement between the companies combines DefiniGEN’s mechanistically relevant iPSC hepatocytes (Opti-Heps) with Atelerix's hydrogel preservation technology, which prevents loss of function and enables even sensitive samples to remain stable at ambient temperatures for up to two weeks.

From Defini Gen 3 Jun 2024

Garlic proves potent in reducing blood sugar and cholesterol, study reveals

Study confirms garlic's significant benefits in lowering blood glucose and lipid levels, offering a natural remedy for metabolic disorders.

2 Jun 2024

Type 2 diabetes linked to higher cancer risk, especially with diabetic retinopathy, study finds

A recent study in BMC Medicine found that type 2 diabetes significantly increases the risk of various cancers, with the risk being even higher in patients with diabetic retinopathy (DR).

2 Jun 2024

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

A recent study in Nature Communications found that intermittent fasting with protein pacing (IF-P) is more effective than continuous calorie restriction (CR) in improving gut microbiota and metabolomic profiles, leading to greater weight and fat loss.

2 Jun 2024

Ketones show promise in preventing cognitive decline and neurodegeneration

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester have identified mechanisms in the brain's hippocampal network that are rescued by ketones.

31 May 2024

Non-coding gene mutation linked to monogenic neurodevelopmental disorders

Researchers at the Icahn School of Medicine at Mount Sinai and others have identified a neurodevelopmental disorder, caused by mutations in a single gene, that affects tens of thousands of people worldwide.

31 May 2024

RNA interference agent plozasiran targets APOC3 for effective mixed hyperlipidemia treatment

Researchers evaluate the efficacy of plazosiran treatment on fasting triglyceride levels in adult patients with mixed hyperlipidemia.

31 May 2024

Stem cell breakthrough: EPHA2 protein may hold key to safer regenerative therapies

Pluripotent stem cells (PSCs) are a type of stem cells capable of developing into various cell types. Over the past few decades, scientists have been working towards the development of therapies using PSCs.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

Statins may block an inflammation pathway involved in the development of cancer

A new study led by investigators from Mass General Cancer Center, a founding member of the Mass General Brigham healthcare system, reveals that statins-;commonly used cholesterol-lowering drugs-;may block a particular pathway involved in the development of cancer that results from chronic inflammation.

30 May 2024

New antibiotic lolamicin shows promise in fighting drug-resistant infections

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.

29 May 2024

Microplastics: Invisible to the eye but severely harmful to pregnancy and metabolic outcomes

The effects of polystyrene microplastics on pregnancy outcomes and glucose metabolism.

29 May 2024

New point-of-care test revolutionizes toxoplasmosis screening

An inexpensive, accurate test that detects infections with the parasite Toxoplasma gondii can provide results within 30 minutes from a finger-prick in a doctor's office or within an hour from a small blood sample tested in a local medical laboratory.

28 May 2024

Discovery of promising protein candidate opens new avenues for treating metabolic disorders

A University of Saskatchewan (USask) research team's discovery of the additional health benefits of an appetite-suppressing protein has doubled the potential for scientists to find new avenues for treating obesity and metabolic disorders in animals and people.

28 May 2024

Oral semaglutide shows promising results for type 2 diabetes in routine clinical settings

Semaglutide and its effects on glycemic control, body weight (BW), and tolerability in routine clinical practice.

28 May 2024

Researchers identify novel way to potentially slow down or halt Alzheimer’s progression

Researchers at the Icahn School of Medicine at Mount Sinai have made a significant breakthrough in Alzheimer's disease research by identifying a novel way to potentially slow down or even halt disease progression.

27 May 2024

Evaluating systemic thrombolysis for acute portal vein thrombosis in cirrhotic patients

The prevalence of Portal Vein Thrombosis (PVT) varies significantly at different stages of liver disease: 10% in compensated patients, 17% in decompensated patients, 9% in those with acute decompensated cirrhosis, and 2-26% in post-liver transplant patients.

24 May 2024

The case of the armadillo: Is it spreading leprosy in Florida?

In an open-air barn at the edge of the University of Florida, veterinarian Juan Campos Krauer examines a dead armadillo's footpads and ears for signs of infection.

24 May 2024

Liver News and Research

Two diabetes medications more beneficial in preventing major cardiovascular events

Childhood inactivity linked to increased risk of liver disease by young adulthood

DefiniGEN and Atelerix collaborate to ship in vitro cell models internationally without the need for freezing or cryopreservation

Garlic proves potent in reducing blood sugar and cholesterol, study reveals

Type 2 diabetes linked to higher cancer risk, especially with diabetic retinopathy, study finds

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

Ketones show promise in preventing cognitive decline and neurodegeneration

Non-coding gene mutation linked to monogenic neurodevelopmental disorders

RNA interference agent plozasiran targets APOC3 for effective mixed hyperlipidemia treatment

Stem cell breakthrough: EPHA2 protein may hold key to safer regenerative therapies

Existing drug alleviates symptoms of a rare genetic syndrome

Statins may block an inflammation pathway involved in the development of cancer

New antibiotic lolamicin shows promise in fighting drug-resistant infections

Microplastics: Invisible to the eye but severely harmful to pregnancy and metabolic outcomes

New point-of-care test revolutionizes toxoplasmosis screening

Discovery of promising protein candidate opens new avenues for treating metabolic disorders

Oral semaglutide shows promising results for type 2 diabetes in routine clinical settings

Researchers identify novel way to potentially slow down or halt Alzheimer’s progression

Evaluating systemic thrombolysis for acute portal vein thrombosis in cirrhotic patients

The case of the armadillo: Is it spreading leprosy in Florida?

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