Ovaries News and Research

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Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature."

31 Oct 2023

New study challenges long-held belief about how chemotherapy works

A new study from the University of Wisconsin–Madison suggests that chemotherapy may not be reaching its full potential, in part because researchers and doctors have long misunderstood how some of the most common cancer drugs actually ward off tumors.

26 Oct 2023

Study explores sex-specific effects in Alzheimers disease pathology

The role of biological sex in the development and progression of Alzheimer's Disease (AD).

19 Oct 2023

Study sheds light on how NAD+ levels decline with age in the ovaries, affecting fertility

A woman's fertility normally decreases by her late 30s with reproductive function eventually ceasing at menopause.

18 Oct 2023

New blood test could detect ovarian cancer early, improve treatment

High-grade serous ovarian carcinoma (HGSOC) is the most common type of ovarian cancer. It is also the most lethal form, in part because clinicians do not have effective ways to screen women for it during the cancer's early stages, when it's easiest to treat.

10 Oct 2023

New device simulates human diseases in multiple organs

Imagine a device smaller than a toddler's shoebox that can simulate any human disease in multiple organs or test new drugs without ever entering -; or harming -; the body.

4 Oct 2023

Key player in ovarian cancer may have implications for PCOS

Researchers explore the involvement and altered expression of BBOX1-AS1 and microRNA-19b in polycystic ovary syndrome.

26 Sep 2023

Is presence of a premenstrual disorder associated with higher risk of early menopause and menopause-related vasomotor symptoms?

A new paper explores how PMDs affect the time of menopause and the severity of vasomotor menopausal symptoms like hot flashes.

21 Sep 2023

Mapping the human body one cell at a time: New study reveals the intricate relationship between cell size and count

A study published in PNAS provides a comprehensive look at the relationship between cell size and count across the human body, drawing from over 1,500 sources and identifying around 400 unique cell types. The research reveals an almost inverse relationship between cell size and count, offering a quantitative framework that could serve as a baseline for understanding cellular composition and function in various applications.

19 Sep 2023

Study reveals potential negative long-term effects of premenopausal bilateral oophorectomy

Increasing concerns regarding potentially harmful long-term effects of premenopausal bilateral oophorectomy (PBO) have caused a decline in the number of women choosing to proactively remove both ovaries as a precaution to protect against ovarian cancer.

13 Sep 2023

Mesenchymal stem cell-derived extracellular vesicles show promise in PCOS treatment

Polycystic ovary syndrome (PCOS) is a pervasive endocrine disorder that affects millions of women globally, impacting their hormonal balance, fertility and overall well-being.

12 Sep 2023

Research shines light on early life factors that may increase risk of cardiovascular disease in women

Advanced research is casting light on possible early life factors – including poverty, physical or mental abuse – that may impact the rate of egg loss and increase the risk of cardiovascular disease in post-menopausal women.

9 Sep 2023

Keto diet may lower testosterone levels in women with PCOS

The ketogenic (keto) diet may lower testosterone levels in women with polycystic ovary syndrome (PCOS), according to a new paper published in the Journal of the Endocrine Society.

8 Sep 2023

Sex hormones drive differences in male and female mouse kidneys

Female kidneys are known to be more resilient to disease and injury, but males need not despair. A new USC Stem Cell-led study published in Developmental Cell describes not only how sex hormones drive differences in male and female mouse kidneys, but also how lowering testosterone can "feminize" this organ and improve its resilience.

5 Sep 2023

Longer duration of anticoagulation therapy benefits cancer patients with isolated distal DVT

Twelve months of edoxaban is superior to three months for the reduction of thrombotic events in patients with cancer and distal deep vein thrombosis (DVT), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Women with endometriosis have more contact with healthcare providers in the years prior to diagnosis

Beginning as far back as ten years before even being diagnosed, women with endometriosis utilise the healthcare system more than women without this chronic illness.

25 Aug 2023

The role of estrogen in osteoarthritis and lower back pain

Researchers review existing evidence on the association between estrogen, osteoarthritis, and lower back pain.

10 Aug 2023

Hmga1 protein could be an important therapeutic target for osteoporosis

New research published in The FASEB Journal indicates that increasing the expression of a particular gene may help to prevent bone loss associated with postmenopausal osteoporosis.

9 Aug 2023

The effects of oxidative stress on women’s fertility

Scientists review existing literature to assess the relationship between oxidative stress and female infertility.

1 Aug 2023

Black women weigh emerging risks of ‘creamy crack’ hair straighteners

Deanna Denham Hughes was stunned when she was diagnosed with ovarian cancer last year. She was only 32. She had no family history of cancer, and tests found no genetic link. Hughes wondered why she, an otherwise healthy Black mother of two, would develop a malignancy known as a "silent killer."