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Noninvasive ventilation halves hypoxemia risk in emergency intubations: PREOXI trial findings

In current clinical care, most critically ill adults undergoing emergency tracheal intubation receive preoxygenation through an oxygen mask.

13 Jun 2024

Japanese study sheds light on genetic counseling for AATRv amyloidosis

Early detection and treatment of hereditary transthyretin-related amyloidosis via genetic counseling are crucial.

13 Jun 2024

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Imagine a world where breathing is a luxury and a cough marks the sound of an inner battle. Interstitial Lung Disease (ILD), a condition characterised by inflammation and fibrosis, is a major cause of severe respiratory illness and can occur in children.

13 Jun 2024

Funding instability plagues program that brings docs to underserved areas

For Diana Perez, a medical resident at the Family Health Center of Harlem, the handwritten thank-you note she received from a patient is all the evidence she needs that she has chosen the right training path.

13 Jun 2024

Replacing TV time with light activity or sleep boosts healthy aging odds

Sedentary behavior reduces the odds of healthy aging, while light physical activity increases them. Replacing TV time with light activity, exercise, or sleep improves healthy aging odds.

13 Jun 2024

Combining donepezil and memantine extends lives of Alzheimer's patients, study finds

Alzheimer's disease is the world's most common neurodegenerative disease, affecting more than 50 million people globally.

12 Jun 2024

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals-;a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD).

12 Jun 2024

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

In response to stressful or dangerous stimuli, nerve cells in the spinal cord activate involuntary, autonomic reflexes often referred to as "fight or flight" responses.

12 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy -; a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers -; is low, despite a Food and Drug Administration warning.

12 Jun 2024

Changing antibiotic delivery method improves sepsis outcomes globally

Changing the way antibiotics are given to adult patients with sepsis will save thousands of lives a year globally, according to research by The University of Queensland and The George Institute for Global Health.

12 Jun 2024

Synthetic cell mimics immune response via symmetry breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

12 Jun 2024

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia.

12 Jun 2024

Multi-center study validates systemic score in identifying high-risk patients with Still's disease

A multi-centre, observational, prospective study was designed to evaluate the clinical usefulness of the systemic score in predicting life-threatening evolution – defined as the development of macrophage activation syndrome (MAS) and/or mortality.

12 Jun 2024

HiDEF-seq technique reveals the origins of DNA mutations in single strands

Mutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer.

12 Jun 2024

Climate change-related environmental stressors associated with increased CVD mortality

Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for approximately one in every three deaths, with more than 20 million deaths reported in 2021 according to a 2024 World Heart Federation report.

12 Jun 2024

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

The nasal microbiota of intensive care unit (ICU) patients effectively distinguishes sepsis from non-septic cases and outperforms analyzing the gut microbiota to predict sepsis, according to a new study published in Microbiology Spectrum, a journal of the American Society for Microbiology.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

Combining anlotinib with STUPP regimen improves survival in glioblastoma patients

Glioblastoma multiforme (GBM) is among the most aggressive forms of brain tumors, with few effective treatment options and a bleak prognosis.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Low-cost quality improvement program lowers mortality in El Salvador's pediatric ICU

Pediatric intensive care units (PICUs) in low and middle-income countries see elevated mortality rates, often 10 times higher than those in high-income countries.

12 Jun 2024

Medicine News and Research

Noninvasive ventilation halves hypoxemia risk in emergency intubations: PREOXI trial findings

Japanese study sheds light on genetic counseling for AATRv amyloidosis

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Funding instability plagues program that brings docs to underserved areas

Replacing TV time with light activity or sleep boosts healthy aging odds

Combining donepezil and memantine extends lives of Alzheimer's patients, study finds

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

Changing antibiotic delivery method improves sepsis outcomes globally

Synthetic cell mimics immune response via symmetry breaking

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Multi-center study validates systemic score in identifying high-risk patients with Still's disease

HiDEF-seq technique reveals the origins of DNA mutations in single strands

Climate change-related environmental stressors associated with increased CVD mortality

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

Enhancing CAR-T cell therapy with biodegradable scaffolds

Combining anlotinib with STUPP regimen improves survival in glioblastoma patients

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Low-cost quality improvement program lowers mortality in El Salvador's pediatric ICU

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From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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