Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

A recent review outlines the necessary factors for widespread implementation and interpretation of Alzheimer's disease blood-based biomarkers (BBMs) at the population level, emphasizing the potential for early detection and improved diagnosis.

14 Jun 2024

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

The nasal microbiota of intensive care unit (ICU) patients effectively distinguishes sepsis from non-septic cases and outperforms analyzing the gut microbiota to predict sepsis, according to a new study published in Microbiology Spectrum, a journal of the American Society for Microbiology.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Few people in the UK with early stage Alzheimer's disease are likely to be suitable for the latest drugs which aim to halt progress of the condition, yet many are nevertheless likely to be referred for these treatments, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

11 Jun 2024

Breathing New Life into Diagnostics: Plasmion's SICRIT® Technology

Revolutionizing Non-Invasive Diagnostics with Plasmion’s SICRIT Breath Analysis.

From Plasmion 11 Jun 2024

Precision-guided treatment boosts outcomes in children with high-risk cancers

Study reveals that precision-guided treatment (PGT) improves outcomes in high-risk pediatric cancer patients, but clinical adoption remains low due to physician uncertainty and lack of long-term survival data.

10 Jun 2024

Host RNA incorporation linked to chronic hepatitis E infection

If the virus incorporates host genetic segments into its genome, the infection may become chronic.

10 Jun 2024

New brain connectivity model predicts dementia years before diagnosis

Whether the default-mode network (DMN) effective connectivity can predict future dementia diagnosis at the individual level.

10 Jun 2024

Surprising link between a diverse oral microbiome and better cognitive function in aging

Study found that higher oral microbiome diversity is linked to better cognitive function and fewer memory issues in older US adults, highlighting the "oral-brain axis."

9 Jun 2024

Novel PET radiotracer enables same-day imaging of gastrointestinal cancer biomarker

A new PET radiotracer enables same-day imaging of the important gastrointestinal cancer biomarker known as Claudin18.2 (CLDN18.2).

6 Jun 2024

New method provides a more accurate way to predict dementia up to nine years before diagnosis

Researchers at Queen Mary University of London have developed a new method for predicting dementia with over 80% accuracy and up to nine years before a diagnosis.

6 Jun 2024

How a low-nicotine cigarette policy could improve public health

A recent study in The Lancet Regional Health shows low-nicotine cigarettes significantly reduce daily cigarette use and increase smoke-free days, even when alternative nicotine delivery systems are available.

5 Jun 2024

Eye-tracking measures could help make the right autism diagnosis sooner

Researchers investigated the reliability of eye-tracking biological markers in distinguishing autistic children from non-autistic ones during clinical evaluations in community-based settings.

5 Jun 2024

Mediterranean dietary adherence can reduce mortality risk in women

The association between Mediterranean diet adherence and any-cause mortality risk.

5 Jun 2024

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

The combination of the antibody amivantamab and lazertinib, a drug targeting EGFR, shows better clinical benefits compared to standard treatment in patients with advanced or metastatic non-small cell lung cancer with EGFR gene mutations who also present one of these poor prognosti markers: brain and/or liver metastases, p53 gene co-mutations, or the presence of circulating tumor DNA.

4 Jun 2024

SCIEX launches new data independent acquisition, ZT Scan DIA, at ASMS 2024

At ASMS 2024, SCIEX, a global leader in life science analytical technologies, introduces ZT Scan DIA for LC-MS/MS, the next generation in data-independent acquisition (DIA) that leverages the combination of the quadrupole dimension with the rich MS2 data attainable from the Zeno trap.

From SCIEX 4 Jun 2024

Omega-3 supplements show promise in battling osteoarthritis

A recent study in Nutrients reviewed the efficacy of omega-3 polyunsaturated fatty acids (PUFAs) in slowing the progression of osteoarthritis (OA) by reducing inflammation and supporting joint health.

2 Jun 2024

Stress and pain linked to worse outcomes in HER2-positive breast cancer patients

Secondary analyses of a phase 3 clinical trial have revealed that breast cancer patients who reported high levels of pain and stress were more likely than their study peers to experience worse invasive disease-free survival (iDFS) and worse overall survival (OS).

31 May 2024

Eye-tracking technology offers earlier, more accurate autism diagnosis

Nearly 3% of all children in the United States are diagnosed with autism, according to the Centers for Disease Control and Prevention.

31 May 2024

Polygenic risk score shows potential to predict survival outcomes in breast cancer patients

Data from a large prospective cohort study reveal that a polygenic risk score has the potential to predict survival outcomes in patients with breast cancer.

31 May 2024

Biomarker News and Research

Further Reading

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

UD researchers pioneer universal, economical method for proteomics sample preparation

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Breathing New Life into Diagnostics: Plasmion's SICRIT® Technology

Precision-guided treatment boosts outcomes in children with high-risk cancers

Host RNA incorporation linked to chronic hepatitis E infection

New brain connectivity model predicts dementia years before diagnosis

Surprising link between a diverse oral microbiome and better cognitive function in aging

Novel PET radiotracer enables same-day imaging of gastrointestinal cancer biomarker

New method provides a more accurate way to predict dementia up to nine years before diagnosis

How a low-nicotine cigarette policy could improve public health

Eye-tracking measures could help make the right autism diagnosis sooner

Mediterranean dietary adherence can reduce mortality risk in women

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

SCIEX launches new data independent acquisition, ZT Scan DIA, at ASMS 2024

Omega-3 supplements show promise in battling osteoarthritis

Stress and pain linked to worse outcomes in HER2-positive breast cancer patients

Eye-tracking technology offers earlier, more accurate autism diagnosis

Polygenic risk score shows potential to predict survival outcomes in breast cancer patients

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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