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Life's Essential 8: key to reducing heart disease and mortality through epigenetics

Whether DNA methylation-based epigenetic age biomarkers mediate the associations between LE8 score and risks of CVD, CVD-specific mortality, and all-cause mortality.

31 May 2024

Is there an association between fatherhood and cardiovascular outcomes?

Associations between fatherhood and cardiovascular health (CVH), disease (CVD), and mortality.

31 May 2024

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers demostrate that durable asthma remission can be achieved with engineered and long-lived CAR T-cell treatment in mice.

31 May 2024

RNA interference agent plozasiran targets APOC3 for effective mixed hyperlipidemia treatment

Researchers evaluate the efficacy of plazosiran treatment on fasting triglyceride levels in adult patients with mixed hyperlipidemia.

31 May 2024

Researchers uncover two classes of genetic causes for pediatric chordoma

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.

30 May 2024

Notre Dame study identifies high-risk population for CAUTIs due to fibrinolytic deficiencies

Urinary catheters are required for nearly every surgical procedure. However, a major challenge for the health care industry is predicting who may develop catheter-associated urinary tract infections (CAUTIs) and when these infections may lead to death.

30 May 2024

Engineered immunogens show promise in inducing HIV broadly neutralizing antibodies

Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals' immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs).

30 May 2024

Three-year study shows lingering effects of COVID-19

New findings on long COVID -; long-term effects on health experienced by many who have had COVID-19 -; present a good-news, bad-news situation, according to a study at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

30 May 2024

Genomic evidence of prenatal origins in childhood acute myeloid leukemia

A team of researchers from the Institute of Oncology of the University of Oviedo (IUOPA), the Josep Carreras leukemia Research Institute, the University of Barcelona and the Centre for Biomedical Research in Cancer Network (CIBERONC) have demonstrated that some childhood leukemia originate during embryonic development, although they do not manifest after a few months after birth.

30 May 2024

Understanding the long-term effects and safety of testosterone therapy in transgender men

Transgender individuals often face unique challenges in aligning their physical bodies with their true gender identity.

30 May 2024

How tight binding between immune cells dictates T cell cancer-fighting ability

Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors.

30 May 2024

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Aging-related physiological decline and the accumulation of senescent or aging cells in bodily tissues can trigger a number of diseases.

30 May 2024

Newly discovered lincRNA controls the development and function of regulatory T cells

The T cells in our blood fight against cancer, viruses and bacteria. Specific regulatory T cells are required to control faulty immune responses, and disruption in their function may lead to autoimmune diseases or cancer.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

Female and male heart failure may require distinct treatments

A new study from the UC Davis School of Medicine found striking differences at the cellular level between male and female mice with heart failure with preserved ejection fraction (HFpEF).

30 May 2024

Safety-net health clinics cut services and staff amid Medicaid ‘unwinding’

One of Montana's largest health clinics that serves people in poverty has cut back services and laid off workers.

30 May 2024

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

A recent review in Signal Transduction and Targeted Therapy highlights the role of exercise-induced molecules, exerkines, in disease prevention and treatment, emphasizing their molecular mechanisms and therapeutic potential.

29 May 2024

Delayed multiple sclerosis diagnosis underscores need for urgent research and awareness boost, report find

A new report from MS Australia reveals that the average time to diagnose multiple sclerosis is nearly four years, highlighting the urgent need for increased research investment and enhanced awareness.

29 May 2024

Heart-healthy habits keep you biologically young, study shows

A new study in the Journal of the American Heart Association reveals that heart-healthy lifestyle factors are linked to younger biological age and lower cardiovascular disease risk through DNA methylation.

29 May 2024

Oral semaglutide shows significant promise in improving diabetes control and cardiovascular health, study reveals

A recent study in the Journal of Clinical Medicine found that oral semaglutide significantly improves glycemic control and reduces body weight in type 2 diabetes patients after 24 weeks of treatment.

29 May 2024

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Blood News and Research

Life's Essential 8: key to reducing heart disease and mortality through epigenetics

Is there an association between fatherhood and cardiovascular outcomes?

Single infusion of engineered T-cells achieves lasting asthma remission in mice

RNA interference agent plozasiran targets APOC3 for effective mixed hyperlipidemia treatment

Researchers uncover two classes of genetic causes for pediatric chordoma

Notre Dame study identifies high-risk population for CAUTIs due to fibrinolytic deficiencies

Engineered immunogens show promise in inducing HIV broadly neutralizing antibodies

Three-year study shows lingering effects of COVID-19

Genomic evidence of prenatal origins in childhood acute myeloid leukemia

Understanding the long-term effects and safety of testosterone therapy in transgender men

How tight binding between immune cells dictates T cell cancer-fighting ability

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Newly discovered lincRNA controls the development and function of regulatory T cells

Existing drug alleviates symptoms of a rare genetic syndrome

Female and male heart failure may require distinct treatments

Safety-net health clinics cut services and staff amid Medicaid ‘unwinding’

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

Delayed multiple sclerosis diagnosis underscores need for urgent research and awareness boost, report find

Heart-healthy habits keep you biologically young, study shows

Oral semaglutide shows significant promise in improving diabetes control and cardiovascular health, study reveals

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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