Clinical Trial News and Research

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Global study confirms pantoprazole's role in reducing upper GI bleeding in the ICU

A widely available drug helps prevent upper gastrointestinal bleeding in critically ill adults on a breathing machine, according to the results of a global study and meta-analysis led by researchers at McMaster University.

14 Jun 2024

EULAR launches ENTRI initiative to boost rheumatic disease research across Europe

The European Alliance of Associations for Rheumatology (EULAR) is proud to announce the launch of the EULAR Network of TRIal Centres (ENTRI) initiative.

14 Jun 2024

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

A recent review outlines the necessary factors for widespread implementation and interpretation of Alzheimer's disease blood-based biomarkers (BBMs) at the population level, emphasizing the potential for early detection and improved diagnosis.

14 Jun 2024

New armored CAR T cell therapy boosts response in Relapsed non-Hodgkin lymphoma patients

While CAR T cell therapy has revolutionized treatment for many blood cancers, including non-Hodgkin lymphoma (NHL), many patients who receive CAR T cell therapy do not experience a long-term remission.

13 Jun 2024

AI-driven alerts improve patient care escalation and survival rates in hospitals

Deploying and evaluating a machine learning intervention to improve clinical care and patient outcomes is a key step in moving clinical deterioration models from byte to bedside, according to a June 13 editorial in Critical Care Medicine that comments on a Mount Sinai study published in the same issue.

13 Jun 2024

Study sheds light on pediatric DIPG tumor mechanisms

Researchers at the University of Michigan Health Rogel Cancer Center are one step closer to understanding how pediatric DIPG tumors work.

13 Jun 2024

Study advocates for liberal blood transfusions in TBI intensive care

Increased use of blood transfusions after major traumatic brain injury could help people hospitalized in intensive care units regain greater functional independence and a better quality of life.

13 Jun 2024

New psychotherapy shows promise in reducing chronic pain for older veterans

A new study led by UCLA Health and the U.S. Veterans Affairs Office found chronic pain among older adults could be significantly reduced through a newly developed psychotherapy that works by confronting past trauma and stress-related emotions that can exacerbate pain symptoms.

13 Jun 2024

Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis

Early therapeutic interventions in inflammatory rheumatic diseases have proven successful in inducing drug-free remission, and EULAR - The European Alliance of Associations for Rheumatology - recommends early intervention in arthritis, since conventional synthetic disease-modifying antirheumatic drugs (csDMARD) have been shown to slow disease progression in both rheumatoid and psoriatic arthritis.

13 Jun 2024

Research points to a potential approach to mitigating diabetes risk from antipsychotic medications

New University of Pittsburgh research points to a potential approach to reducing the risk of diabetes associated with widely prescribed antipsychotic medications.

13 Jun 2024

Noninvasive ventilation halves hypoxemia risk in emergency intubations: PREOXI trial findings

In current clinical care, most critically ill adults undergoing emergency tracheal intubation receive preoxygenation through an oxygen mask.

13 Jun 2024

MEK inhibitor trametinib shows potential in pediatric JMML treatment

The MEK inhibitor trametinib (Mekinist) was an effective treatment for pediatric patients with relapsed or refractory juvenile myelomonocytic leukemia (JMML) enrolled in a phase II clinical trial, with seven of 10 patients alive after a median of two years.

13 Jun 2024

Changing antibiotic delivery method improves sepsis outcomes globally

Changing the way antibiotics are given to adult patients with sepsis will save thousands of lives a year globally, according to research by The University of Queensland and The George Institute for Global Health.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Enterprise Therapeutics publishes preclinical profile of ETD001, a novel inhaled ENaC blocker

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of people with respiratory diseases, today announced the publication of a peer reviewed study in the Journal of Cystic Fibrosis1.

12 Jun 2024

Antioxidants combat high-fat diet-induced female reproductive issues, study reveals

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Clinical Trial News and Research

Global study confirms pantoprazole's role in reducing upper GI bleeding in the ICU

EULAR launches ENTRI initiative to boost rheumatic disease research across Europe

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

New armored CAR T cell therapy boosts response in Relapsed non-Hodgkin lymphoma patients

AI-driven alerts improve patient care escalation and survival rates in hospitals

Study sheds light on pediatric DIPG tumor mechanisms

Study advocates for liberal blood transfusions in TBI intensive care

New psychotherapy shows promise in reducing chronic pain for older veterans

Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis

Research points to a potential approach to mitigating diabetes risk from antipsychotic medications

Noninvasive ventilation halves hypoxemia risk in emergency intubations: PREOXI trial findings

MEK inhibitor trametinib shows potential in pediatric JMML treatment

Changing antibiotic delivery method improves sepsis outcomes globally

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Enterprise Therapeutics publishes preclinical profile of ETD001, a novel inhaled ENaC blocker

Antioxidants combat high-fat diet-induced female reproductive issues, study reveals

Attenuated virus helps eliminate cancer in mice

Ashwagandha boosts memory and mood in clinical trial

Can lifestyles changes reduce Alzheimer’s risk?

Precision-guided treatment boosts outcomes in children with high-risk cancers

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