Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Release of Unity 2.0: Order, track, and manage your compound collection through one platform

eMolecules has launched a new updated platform that enables medicinal chemists or compound managers to order, track, and manage their compound collection and commercial sources through a more intuitive and flexible system: Unity.

From eMolecules 13 Jun 2024

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Imagine a world where breathing is a luxury and a cough marks the sound of an inner battle. Interstitial Lung Disease (ILD), a condition characterised by inflammation and fibrosis, is a major cause of severe respiratory illness and can occur in children.

13 Jun 2024

From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

In this interview, we speak with Melanie Leveridge, Vice President of Discovery Biology at AstraZeneca and Chair of the Board for ELRIG UK, to discuss her extensive career in the pharmaceutical industry, her role in fostering scientific innovation, and her vision for ELRIG's future.

From ELRIG (UK) Ltd. 13 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Newcells Biotech strengthens executive and US team with key appointments

Dr Valeria Chichagova appointed as Director of Technology, Dr Colin Brown as Chief Scientific Officer, and Professor Lyle Armstrong as Scientific Advisor.

From Newcells Biotech 11 Jun 2024

Transforming antibody drug discovery with Epitope Binning-seq

Monoclonal antibodies are crucial therapeutics due to their high specificity and binding affinity for epitopes (the precise sites where an antibody attaches itself to an antigen, triggering an immune response).

10 Jun 2024

Molecular Devices opens custom-built site in Cardiff for manufacturing of patient-derived organoids

Today, Molecular Devices, LLC., a leading high-performance life science solutions provider, officially opened its custom-built site in Cardiff, UK.

8 Jun 2024

Simple peptide modification could unlock a whole class of targets for drug discovery

A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows.

7 Jun 2024

Targeting TGFβ/ROCK2/YAP signaling axis to enhance drug delivery in fibrotic pancreatic cancer

Pancreatic cancer, recognized as one of the deadliest cancers, poses a persistent challenge for medical professionals globally due to its aggressive behavior and resistance to conventional therapies.

5 Jun 2024

SCIEX launches new data independent acquisition, ZT Scan DIA, at ASMS 2024

At ASMS 2024, SCIEX, a global leader in life science analytical technologies, introduces ZT Scan DIA for LC-MS/MS, the next generation in data-independent acquisition (DIA) that leverages the combination of the quadrupole dimension with the rich MS2 data attainable from the Zeno trap.

From SCIEX 4 Jun 2024

New vessel-chip deployment platform holds promise for personalized drug testing

The pharmaceutical drug development and approval process is a multi-step undertaking that requires a plethora of testing before reaching the market.

31 May 2024

Study may facilitate the development of new personalized treatments for schizophrenia An International Study Publi...

An international study led by the Hospital del Mar Medical Research Institute, in collaboration with researchers from the Neuropsychopharmacology Group at the University of the Basque Country (UPV/EHU) and researchers from the CIBER of Mental Health (CIBERSAM), and published in Nature Communications, may facilitate the creation of new personalized treatments for people diagnosed with schizophrenia.

30 May 2024

Research reveals how Regnase-1 deficiency enhances NK cell tumor killing

Natural killer (NK) cells play a crucial role in the first line of host defense by eliminating bacteria, viruses, and mutated cells that might become cancer cells.

30 May 2024

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

In this Interview, NewsMedical speaks with Amy Landreman about NanoBRET® Technology and its role in cellular target engagement.

From Promega Corporation 30 May 2024

Secarna Pharmaceuticals and Orbit Discovery enter collaboration to discover and develop peptide-conjugated targeted antisense oligonucleotide therapeutics

Secarna Pharmaceuticals GmbH & Co. KG (Secarna), a leading independent European antisense drug discovery and development company, and Orbit Discovery Ltd. (Orbit), a leader in the discovery of therapeutic peptide hits, today announced that they have entered into a collaboration to discover and develop peptide-conjugated targeted antisense oligonucleotide (ASO) therapeutics.

From Secarna Pharmaceuticals 29 May 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

Drug Discovery News and Research

Further Reading

Release of Unity 2.0: Order, track, and manage your compound collection through one platform

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

UD researchers pioneer universal, economical method for proteomics sample preparation

Newcells Biotech strengthens executive and US team with key appointments

Transforming antibody drug discovery with Epitope Binning-seq

Molecular Devices opens custom-built site in Cardiff for manufacturing of patient-derived organoids

Simple peptide modification could unlock a whole class of targets for drug discovery

Targeting TGFβ/ROCK2/YAP signaling axis to enhance drug delivery in fibrotic pancreatic cancer

SCIEX launches new data independent acquisition, ZT Scan DIA, at ASMS 2024

New vessel-chip deployment platform holds promise for personalized drug testing

Study may facilitate the development of new personalized treatments for schizophrenia An International Study Publi...

Research reveals how Regnase-1 deficiency enhances NK cell tumor killing

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

Secarna Pharmaceuticals and Orbit Discovery enter collaboration to discover and develop peptide-conjugated targeted antisense oligonucleotide therapeutics

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

Changing the landscape of R&D to build clinical success from the ground up

Phase 1 trial for EBC-129 progresses into dose expansion

Non-hormonal sperm-specific approach offers a promising option for reversible male contraception

Insilico Medicine's leadership to address key challenges in AI drug discovery at BIO Convention

Drug Discovery - Second Edition eBook

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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