Efficacy News and Research

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Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers demostrate that durable asthma remission can be achieved with engineered and long-lived CAR T-cell treatment in mice.

31 May 2024

RNA interference agent plozasiran targets APOC3 for effective mixed hyperlipidemia treatment

Researchers evaluate the efficacy of plazosiran treatment on fasting triglyceride levels in adult patients with mixed hyperlipidemia.

31 May 2024

Study examines prescribing patterns of tricyclic antidepressants for treatment of diabetic peripheral neuropathy

Many adults with diabetes and the associated complication of peripheral neuropathy, which can be painful as well as harmful, are often prescribed drugs at doses and for durations that could impose an increased risk of cognitive impairment.

30 May 2024

Understanding the long-term effects and safety of testosterone therapy in transgender men

Transgender individuals often face unique challenges in aligning their physical bodies with their true gender identity.

30 May 2024

How tight binding between immune cells dictates T cell cancer-fighting ability

Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors.

30 May 2024

Inexpensive “duckbill” N95 becomes the champion in COVID-19 mask effectiveness

In a head-to-head comparison of masks worn by people with active COVID-19, the inexpensive "duckbill" N95 came out on top, stopping 98% of COVID-19 particles in the breath of infected people from escaping into the air.

30 May 2024

Mast cells and PGE2: Key players in controlling asthma inflammation

Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause inflammation during an asthma attack, inducing symptoms such as trouble breathing and narrowing of the airways.

30 May 2024

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

In this Interview, NewsMedical speaks with Amy Landreman about NanoBRET® Technology and its role in cellular target engagement.

From Promega Corporation 30 May 2024

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

A recent review in Signal Transduction and Targeted Therapy highlights the role of exercise-induced molecules, exerkines, in disease prevention and treatment, emphasizing their molecular mechanisms and therapeutic potential.

29 May 2024

Oral semaglutide shows significant promise in improving diabetes control and cardiovascular health, study reveals

A recent study in the Journal of Clinical Medicine found that oral semaglutide significantly improves glycemic control and reduces body weight in type 2 diabetes patients after 24 weeks of treatment.

29 May 2024

COVID-19 boosters targeting omicron subvariants remain effective, but wane over time

Boosters that target the omicron subvariants of SARS-CoV-2 are still providing reasonably durable protection against infection, hospitalization and death from COVID-19, according to new data from a study led by researchers at the UNC Gillings School of Global Public Health.

29 May 2024

Novel method predicts cancer cell behaviors using nano informatics and machine learning

A recent study has introduced a novel method combining nano informatics and machine learning to precisely predict cancer cell behaviors, enabling the identification of cell subpopulations with distinct characteristics like drug sensitivity and metastatic potential.

29 May 2024

New type of immunotherapy shows promising preclinical results against osteosarcoma

A new type of immunotherapy, developed by UCL researchers, has shown promising preclinical results against a bone cancer called osteosarcoma, as part of a study in mice.

29 May 2024

New research highlights a promising approach to tackling for ALS

A recent collaborative research endeavor, published in the prestigious Cell Press journal Cell Reports Medicine, highlights a promising therapeutic avenue for amyotrophic lateral sclerosis (ALS).

29 May 2024

RNA-based therapy shows promise in reducing cholesterol and triglycerides

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood.

29 May 2024

Vaccination remains crucial for preventing avian influenza spread, says study

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Efficacy News and Research

Single infusion of engineered T-cells achieves lasting asthma remission in mice

RNA interference agent plozasiran targets APOC3 for effective mixed hyperlipidemia treatment

Study examines prescribing patterns of tricyclic antidepressants for treatment of diabetic peripheral neuropathy

Understanding the long-term effects and safety of testosterone therapy in transgender men

How tight binding between immune cells dictates T cell cancer-fighting ability

Inexpensive “duckbill” N95 becomes the champion in COVID-19 mask effectiveness

Mast cells and PGE2: Key players in controlling asthma inflammation

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

Oral semaglutide shows significant promise in improving diabetes control and cardiovascular health, study reveals

COVID-19 boosters targeting omicron subvariants remain effective, but wane over time

Novel method predicts cancer cell behaviors using nano informatics and machine learning

New type of immunotherapy shows promising preclinical results against osteosarcoma

New research highlights a promising approach to tackling for ALS

RNA-based therapy shows promise in reducing cholesterol and triglycerides

Vaccination remains crucial for preventing avian influenza spread, says study

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

Evaluating the efficacy of harmol in treating herpes simplex virus-induced keratitis

Why use light scattering to analyze proteins and viral vectors?

GLP-1 receptor agonists effective for weight loss in obesity without diabetes

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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