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Life's Essential 8: key to reducing heart disease and mortality through epigenetics

Whether DNA methylation-based epigenetic age biomarkers mediate the associations between LE8 score and risks of CVD, CVD-specific mortality, and all-cause mortality.

31 May 2024

Researchers uncover two classes of genetic causes for pediatric chordoma

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.

30 May 2024

Study may facilitate the development of new personalized treatments for schizophrenia An International Study Publi...

An international study led by the Hospital del Mar Medical Research Institute, in collaboration with researchers from the Neuropsychopharmacology Group at the University of the Basque Country (UPV/EHU) and researchers from the CIBER of Mental Health (CIBERSAM), and published in Nature Communications, may facilitate the creation of new personalized treatments for people diagnosed with schizophrenia.

30 May 2024

Older adults with a criminal background found to have higher risk of developing dementia

Using national registry data, Carmen Solares Canal identified individuals over fifty and collected data on their criminal convictions and health.

30 May 2024

Advancing protein structure prediction with quantum computing

Researchers from Cleveland Clinic and IBM recently published findings in the Journal of Chemical Theory and Computation that could lay the groundwork for applying quantum computing methods to protein structure prediction.

30 May 2024

New molecular analysis unravels the biological mechanisms of pediatric brain tumors

A study conducted by researchers from the D'Or Institute for Research and Education (IDOR) and the Rede D'Or Pathological Anatomy in conjunction with several North American institutions, including the National Cancer Institute (NIH), used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

In this Interview, NewsMedical speaks with Amy Landreman about NanoBRET® Technology and its role in cellular target engagement.

From Promega Corporation 30 May 2024

Innovative startups leading the charge in alternative proteins to solve global food crisis

A recent review in Nature Communications highlights the crucial role of innovative startups in advancing alternative protein sources to tackle global food security challenges and translate these efforts into commercial applications.

29 May 2024

Heart-healthy habits keep you biologically young, study shows

A new study in the Journal of the American Heart Association reveals that heart-healthy lifestyle factors are linked to younger biological age and lower cardiovascular disease risk through DNA methylation.

29 May 2024

Opioid receptors play unexpected role in gut nervous system development

Researchers at Rice University have revealed a previously unknown function of opioid receptors in the development of the enteric nervous system (ENS), often referred to as the "brain in the gut."

29 May 2024

Foam-based delivery system could revolutionize gene therapies

Foam mixed with medications is already used to treat conditions such as varicose veins, hemorrhoids, wounds on the skin and even hair loss.

29 May 2024

New research highlights a promising approach to tackling for ALS

A recent collaborative research endeavor, published in the prestigious Cell Press journal Cell Reports Medicine, highlights a promising therapeutic avenue for amyotrophic lateral sclerosis (ALS).

29 May 2024

RNA-based therapy shows promise in reducing cholesterol and triglycerides

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood.

29 May 2024

Researchers overturn the prevailing theory for colorectal tumor initiation

Research led by Weill Cornell Medicine provides new evidence that most colorectal cancers begin with the loss of intestinal stem cells, even before cancer-causing genetic alterations appear.

29 May 2024

Study links low oxytocin levels to symptoms of polycystic ovary syndrome

The role of oxytocin (OT) in polycystic ovary syndrome (PCOS).

29 May 2024

Heart healthy behaviors may slow biological aging, research shows

The benefit of better heart health may be associated with the positive impact of heart healthy lifestyle factors on biological aging (the age of the body and its cells), according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

29 May 2024