Immune System News and Research

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Engineered immunogens show promise in inducing HIV broadly neutralizing antibodies

Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals' immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs).

30 May 2024

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Aging-related physiological decline and the accumulation of senescent or aging cells in bodily tissues can trigger a number of diseases.

30 May 2024

Newly discovered lincRNA controls the development and function of regulatory T cells

The T cells in our blood fight against cancer, viruses and bacteria. Specific regulatory T cells are required to control faulty immune responses, and disruption in their function may lead to autoimmune diseases or cancer.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

New antibody shows promise as universal weapon against COVID-19 variants

SARS-CoV-2, the virus that causes COVID-19 disease, continues to evolve and evade current vaccine and therapeutic interventions.

29 May 2024

Foam-based delivery system could revolutionize gene therapies

Foam mixed with medications is already used to treat conditions such as varicose veins, hemorrhoids, wounds on the skin and even hair loss.

29 May 2024

Vaccination remains crucial for preventing avian influenza spread, says study

Vaccination remains the most effective strategy for avian influenza prevention and control in humans, despite varying vaccine efficacy across strains.

29 May 2024

Targeting CD47 to improve osimertinib efficacy in EGFR mutant NSCLC

NSCLC is the leading cause of cancer deaths globally, with EGFR mutations being a common feature in these cancers.

28 May 2024

Study highlights a dietary strategy for health improvement and weight management

A new study by researchers from Arizona State University and their colleagues highlights a dietary strategy for significant health improvement and weight management.

28 May 2024

Understanding the link between EBV-infected B cells and multiple sclerosis

The Wistar Institute's Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author, Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

28 May 2024

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

A multidisciplinary research team at the University of California, Irvine has revealed that the circadian clock – the biological pacemaker that governs daily rhythms in physiological processes, including immune functions – can be leveraged to enhance the efficacy of checkpoint inhibitor cancer therapy.

28 May 2024

New subset of T cells may enhance cancer immunotherapy

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies.

28 May 2024

New antibody therapy shows promise in combating kidney transplant rejection

Antibody-mediated rejection (AMR) is one of the most common causes of kidney transplant failure. To date, however, no treatment has proven effective in combating this complication in the long term.

27 May 2024

Phytochemicals show promise in treating neurological disorders by influencing the gut-brain axis

Researchers reviewed the potential therapeutic effects of phytochemicals on the gut-brain axis, finding they could influence brain function and reduce neurological symptoms by modulating gut microbiota.

26 May 2024

Targeting metabolic pathways to combat Epstein-Barr virus infections

The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers.

24 May 2024

Tattoos could be a risk factor for lymphoma, study suggests

A new study from Lund University in Sweden suggests that tattoos could be a risk factor for cancer in the lymphatic system, or lymphoma.

24 May 2024

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

Vaccinia viruses are therapeutic tools with different biomedical applications depending on the susceptibility characteristics.

24 May 2024

New stem cell transplant approach may expand donor pool for high-risk blood cancer patients

A new treatment approach using an older drug may enable more patients with high-risk blood cancers to receive transplanted stem cells from unrelated, partially matched donors, according to a study conducted by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and colleagues.

23 May 2024

Study sheds light on intricate differences in the brains of people with PTSD and depression

Stress-related disorders like post-traumatic stress disorder and clinical depression are complex conditions influenced by both genetics and our environment.

23 May 2024

Urban indoor gardening boosts skin microbiota diversity and immune function

A one-month indoor gardening period increased the bacterial diversity of the skin and was associated with higher levels of anti-inflammatory molecules in the blood demonstrated a collaborative study between the University of Helsinki, Natural Resources Institute Finland and Tampere University.

23 May 2024

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Immune System News and Research

Engineered immunogens show promise in inducing HIV broadly neutralizing antibodies

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Newly discovered lincRNA controls the development and function of regulatory T cells

Existing drug alleviates symptoms of a rare genetic syndrome

New antibody shows promise as universal weapon against COVID-19 variants

Foam-based delivery system could revolutionize gene therapies

Vaccination remains crucial for preventing avian influenza spread, says study

Targeting CD47 to improve osimertinib efficacy in EGFR mutant NSCLC

Study highlights a dietary strategy for health improvement and weight management

Understanding the link between EBV-infected B cells and multiple sclerosis

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

New subset of T cells may enhance cancer immunotherapy

New antibody therapy shows promise in combating kidney transplant rejection

Phytochemicals show promise in treating neurological disorders by influencing the gut-brain axis

Targeting metabolic pathways to combat Epstein-Barr virus infections

Tattoos could be a risk factor for lymphoma, study suggests

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

New stem cell transplant approach may expand donor pool for high-risk blood cancer patients

Study sheds light on intricate differences in the brains of people with PTSD and depression

Urban indoor gardening boosts skin microbiota diversity and immune function

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