Interferon News and Research

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Blood interferon signature reveals key differences in pediatric-onset Sjögren's disease

Due to differences in clinical presentation and limited knowledge, diagnosing Sjögren's disease in children can be challenging.

14 Jun 2024

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Study found that EBV-specific immune responses in MS patients showed higher IgG titers and cell-mediated reactions to EBV antigens compared to healthy controls, suggesting a complex role of EBV in MS development.

9 Jun 2024

Gene therapy trial: restored hearing in children with hereditary deafness

The safety and effectiveness of binaural adeno-associated virus 1 (AAV1)-human otoferlin (hOTOF) therapy in five children with autosomal recessive deafness 9 (DFNB9).

7 Jun 2024

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Researchers found that young bone marrow transplants rejuvenate aging immune cells, reducing Alzheimer's symptoms in mice models, suggesting a potential therapeutic approach for the disease.

4 Jun 2024

IgG from long COVID patients induces specific symptoms in mice, confirming autoimmunity's role

Researchers found that IgG from long COVID patients induces specific symptoms in mice, suggesting IgG's role in long COVID pathogenesis.

3 Jun 2024

Statins found to prevent chronic inflammation-related cancers by inhibiting interleukin-33

The effects of statins via inhibition of interleukin 33 (IL-33).

3 Jun 2024

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers demostrate that durable asthma remission can be achieved with engineered and long-lived CAR T-cell treatment in mice.

31 May 2024

Research reveals how Regnase-1 deficiency enhances NK cell tumor killing

Natural killer (NK) cells play a crucial role in the first line of host defense by eliminating bacteria, viruses, and mutated cells that might become cancer cells.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

hnRNPM's protective role in protein synthesis precision uncovered

Researchers at Baylor College of Medicine and collaborating institutions have discovered that a protein called hnRNPM helps protect the integrity of the process cells use to make proteins.

30 May 2024

Running therapy matches antidepressants for mental health, surpasses for physical benefits

Researchers found that while both antidepressants and group running therapy effectively improved mental health in patients with anxiety and depression, running therapy had significantly better outcomes for physical health indicators.

26 May 2024

COVID-19 linked to rise in autoimmune lung disease, study finds

A study in eBioMedicine identifies shared immunopathology between SARS-CoV-2 infection and MDA5 autoimmunity, highlighting a surge in MDA5+ cases and interstitial lung disease during the COVID-19 pandemic.

15 May 2024

New study sheds light on interferon combinations' role in lupus variability

In a new study, researchers from Johns Hopkins Medicine say they have uncovered insights as to why lupus symptoms and severity present differently in individuals with the autoimmune condition, which affects up to 1.5 million Americans.

14 May 2024

Curcuminoid compounds show promise against COVID-19 in neuronal cells

The effects of curcumin and curcuminoids on a human neuroblastoma cell line (SH-SY5Y) infected with SARS-CoV-2.

14 May 2024

Combination immunotherapy treatment enhances immune response for people with malignant gliomas

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have pinpointed a combination immunotherapy treatment that enhances the immune response for people with malignant gliomas, an aggressive type of brain tumor that is fast growing and difficult to treat.

9 May 2024

Revvity unveils a new era of automated tuberculosis testing

Revvity, Inc. (NYSE: RVTY) today announced the launch of the Auto-Pure 2400 liquid handler from Allsheng for use with the T-SPOT.TB test. The Auto-Pure 2400 platform is easy to use and designed to provide efficient workflows in the lab. When the accuracy of the T-SPOT.TB test is combined with the efficiency of the Auto-Pure 2400 system, labs, clinicians and ultimately patients, benefit from the resultant powerful solution.

From Revvity 26 Apr 2024

Genetically modified mice reveal key players in immune defense against viruses

Chemokines are signaling proteins that orchestrate the interaction of immune cells against pathogens and tumors.

25 Apr 2024

MIT study reveals circadian impact on drug metabolism in engineered livers

Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

Interferon News and Research

Blood interferon signature reveals key differences in pediatric-onset Sjögren's disease

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Gene therapy trial: restored hearing in children with hereditary deafness

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

IgG from long COVID patients induces specific symptoms in mice, confirming autoimmunity's role

Statins found to prevent chronic inflammation-related cancers by inhibiting interleukin-33

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Research reveals how Regnase-1 deficiency enhances NK cell tumor killing

Existing drug alleviates symptoms of a rare genetic syndrome

hnRNPM's protective role in protein synthesis precision uncovered

Running therapy matches antidepressants for mental health, surpasses for physical benefits

COVID-19 linked to rise in autoimmune lung disease, study finds

New study sheds light on interferon combinations' role in lupus variability

Curcuminoid compounds show promise against COVID-19 in neuronal cells

Combination immunotherapy treatment enhances immune response for people with malignant gliomas

Revvity unveils a new era of automated tuberculosis testing

Genetically modified mice reveal key players in immune defense against viruses

MIT study reveals circadian impact on drug metabolism in engineered livers

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

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