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TIMP-1 protein found to boost immune system's fight against cancer

Researchers at the University of Turku in Finland have found a new function for an existing protein.

14 Jun 2024

The hidden genetic switches influencing human height and bone health

In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone.

14 Jun 2024

Partnership with Microsaic Systems for Optimer-enabled water monitoring

New binders will be developed to multiple waterborne pathogens. Optimer will support continuous water monitoring for rapid detection.

From Aptamer Group 14 Jun 2024

New recommendations on vitamin D intake for children, pregnant people, adults over 75 and those with high-risk prediabetes

In the present study, researchers developed guidelines for vitamin D supplementation to prevent disease.

14 Jun 2024

Short-term alcohol abstinence worsens gut health in alcohol use disorder patients

A study published in PLoS ONE found that short-term abstinence from alcohol in AUD patients exacerbates gut dysbiosis and increases mental distress, contrary to expected improvements.

14 Jun 2024

Case study sheds light on CAR-T therapy-related secondary cancers

A new detailed analysis of a patient's second cancer after receiving CAR-T therapy for the initial cancer provides rare but important insights intended to offer helpful guidance for oncologists and pathologists about the clinical presentation and pathologic features involved in a CAR-T related second cancer.

13 Jun 2024

Targeting basophils to revitalize cytotoxic T-cells in tumor microenvironment

The ecosystem that surrounds a tumor, also known as the tumor microenvironment, includes immune cells, tissues, blood vessels and other cells that interact with each other and with the tumor.

13 Jun 2024

AI-driven simulations revolutionize robotic exoskeletons for enhanced mobility

A team of researchers have demonstrated a new method that leverages AI and computer simulations to train robotic exoskeletons that can help users save energy while walking, running, and climbing stairs.

13 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy -; a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers -; is low, despite a Food and Drug Administration warning.

12 Jun 2024

Changing antibiotic delivery method improves sepsis outcomes globally

Changing the way antibiotics are given to adult patients with sepsis will save thousands of lives a year globally, according to research by The University of Queensland and The George Institute for Global Health.

12 Jun 2024

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

The nasal microbiota of intensive care unit (ICU) patients effectively distinguishes sepsis from non-septic cases and outperforms analyzing the gut microbiota to predict sepsis, according to a new study published in Microbiology Spectrum, a journal of the American Society for Microbiology.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Using an advanced artificial intelligence tool, researchers at the Icahn School of Medicine at Mount Sinai have identified rare coding variants in 17 genes that shed light on the molecular basis of coronary artery disease (CAD), the leading cause of morbidity and mortality worldwide.

11 Jun 2024